Zobrazeno 1 - 10
of 683
pro vyhledávání: '"VAMP2"'
Autor:
Daniela Felício, Andreia Dias, Sandra Martins, Estefânia Carvalho, Alexandra M. Lopes, Nádia Pinto, Carolina Lemos, Mariana Santos, Miguel Alves-Ferreira
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Migraine is a common and complex neurological disease potentially caused by a polygenic interaction of multiple gene variants. Many genes associated with migraine are involved in pathways controlling the synaptic function and neurotransmitte
Externí odkaz:
https://doaj.org/article/99d01bb37c1441798b159c5e6deff1eb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundSynaptic transmission between neurons and glioma cells can promote glioma progression. The soluble N-ethylmaleimide-sensitive fusion factor attachment protein receptors (SNARE) play a key role in synaptic functions. We aimed to construct an
Externí odkaz:
https://doaj.org/article/ce24871934b2412cb67429512d072d2d
Akademický článek
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Autor:
Nikita Raj, Lilo Greune, Martin Kahms, Karina Mildner, Rico Franzkoch, Olympia Ekaterini Psathaki, Thomas Zobel, Dagmar Zeuschner, Jürgen Klingauf, Volker Gerke
Publikováno v:
Advanced Science, Vol 10, Iss 13, Pp n/a-n/a (2023)
Abstract The plasma membrane of a cell is subject to stresses causing ruptures that must be repaired immediately to preserve membrane integrity and ensure cell survival. Yet, the spatio‐temporal membrane dynamics at the wound site and the source of
Externí odkaz:
https://doaj.org/article/aa493a636a924d8e9c05972c84759dcb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Vesicle-associated membrane protein 2 (VAMP2, also known as synaptobrevin-2), encoded by VAMP2 in humans, is a key component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. VAMP2 combined with syntaxin-1A
Externí odkaz:
https://doaj.org/article/91a5fe89673543fdad586f8ddbd6bb90
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pancreatic cancer is the 7th leading cause of cancer death worldwide, and its incidence and mortality rate have been on the rise in recent years in Western developed countries. The specificity of the disease and the lack of appropriate treatments hav
Externí odkaz:
https://doaj.org/article/296945c325ea475a9c7c371a80180844
Autor:
Andrea Saul Costa, Evelyn Ferri, Franca Rosa Guerini, Paolo Dionigi Rossi, Beatrice Arosio, Mario Clerici
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Vascular alterations often overlap with neurodegeneration, resulting in mixed forms of dementia (MD) that are hard to differentiate from Alzheimer’s Disease (AD). The 26 bp intergenic polymorphism of VAMP2, a key component of SNARE complex, as well
Externí odkaz:
https://doaj.org/article/2dad82c8fa3c4abaafabcd66c86e6cdd
Autor:
Zhiying Li, Bolin Li, Jiansheng Lu, Xuyang Liu, Xiao Tan, Rong Wang, Peng Du, Shuo Yu, Qing Xu, Xiaobin Pang, Yunzhou Yu, Zhixin Yang
Publikováno v:
Toxins, Vol 15, Iss 3, p 200 (2023)
Botulinum neurotoxins (BoNTs) can cause nerve paralysis syndrome in mammals and other vertebrates. BoNTs are the most toxic biotoxins known and are classified as Class A biological warfare agents. BoNTs are mainly divided into seven serotypes A-G and
Externí odkaz:
https://doaj.org/article/1094d4f457e24d2cbfac4f114680305b
Autor:
Kaitlyn E. Fouke, M. Elizabeth Wegman, Sarah A. Weber, Emily B. Brady, Cristina Román-Vendrell, Jennifer R. Morgan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neurotransmission relies critically on the exocytotic release of neurotransmitters from small synaptic vesicles (SVs) at the active zone. Therefore, it is essential for neurons to maintain an adequate pool of SVs clustered at synapses in order to sus
Externí odkaz:
https://doaj.org/article/0886625b70a34663bc79bc0ace005b54
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract We aimed to explore the function and underlying mechanism of highly upregulated in liver cancer (HULC; an long noncoding RNAs) in hepatocellular carcinoma (HCC) and chemosensitivity of oxaliplatin (Oxa). The expression of HULC, miR‐383‐5
Externí odkaz:
https://doaj.org/article/b51f103ee9b9419f823c1ff9d4153135