Zobrazeno 1 - 10 of 112 pro vyhledávání: '"VALERY GMYR"'
1
Akademický článek
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
Autor: Weidong Zhang, Ayako Miura, Md Moin Abu Saleh, Koichiro Shimizu, Yuichiro Mita, Ryota Tanida, Satoshi Hirako, Seiji Shioda, Valery Gmyr, Julie Kerr-Conte, Francois Pattou, Chunhuan Jin, Yoshikatsu Kanai, Kazuki Sasaki, Naoto Minamino, Hideyuki Sakoda, Masamitsu Nakazato
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Insulin secretion from pancreatic β cells is regulated by multiple stimuli, including nutrients, hormones, neuronal inputs, and local signalling. Amino acids modulate insulin secretion via amino acid transporters expressed on β cells. The
Externí odkaz: https://doaj.org/article/13b28fe0aa5b471fb9ba3b62af44728f
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2
Akademický článek
Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study
Autor: Thibault Duburcq, Arthur Durand, Antoine Tournoys, Viviane Gnemmi, Valery Gmyr, François Pattou, Mercedes Jourdain, Fabienne Tamion, Emmanuel Besnier, Sebastien Préau, Erika Parmentier-Decrucq, Daniel Mathieu, Julien Poissy, Raphaël Favory
Publikováno v: Annals of Intensive Care, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background Sodium lactate seemed to improve fluid balance and avoid fluid overload. The objective of this study was to determine if these beneficial effects can be at least partly explained by an improvement in disseminated intravascular coa
Externí odkaz: https://doaj.org/article/8d08b3444dc6434fad0002e84f10b2fc
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3
Akademický článek
Comparison of fluid balance and hemodynamic and metabolic effects of sodium lactate versus sodium bicarbonate versus 0.9% NaCl in porcine endotoxic shock: a randomized, open-label, controlled study
Autor: Thibault Duburcq, Arthur Durand, Anne-Frédérique Dessein, Joseph Vamecq, Jean-Claude Vienne, Dries Dobbelaere, Karine Mention, Claire Douillard, Patrice Maboudou, Valery Gmyr, François Pattou, Mercé Jourdain, Fabienne Tamion, Julien Poissy, Daniel Mathieu, Raphaël Favory
Publikováno v: Critical Care, Vol 21, Iss 1, Pp 1-9 (2017)
Abstract Background Sodium lactate has been shown to improve hemodynamics and avoid fluid overload. The objective of this study was to confirm a beneficial effect on fluid balance with sodium lactate infusion and to specify whether the advantage of l
Externí odkaz: https://doaj.org/article/aae8f52729e047b5aa88c24f4c1e2e7b
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4
Akademický článek
Human Recombinant Antithrombin (ATryn®) Administration Improves Survival and Prevents Intravascular Coagulation after Intraportal Islet Transplantation in a Piglet Model
Autor: Valery Gmyr, Caroline Bonner, Ericka Moerman, Antoine Tournoys, Nathalie Delalleau, Audrey Quenon, Julien Thevenet, Mikael Chetboun, Julie Kerr-Conte, François Pattou, Thomas Hubert, Merce Jourdain M.D., Ph.D.
Publikováno v: Cell Transplantation, Vol 26 (2017)
Human islet transplantation is a viable treatment option for type 1 diabetes mellitus (T1DM). However, pancreatic islet inflammation after transplantation induced by innate immune responses is likely to hinder graft function. This is mediated by inco
Externí odkaz: https://doaj.org/article/f5de30a239f743ffa2e9bd4344aef351
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5
Akademický článek
Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells
Autor: Antoine Bertin, Famara Sane, Valery Gmyr, Delphine Lobert, Arthur Dechaumes, Julie Kerr-Conte, François Pattou, Didier Hober
Publikováno v: Viruses, Vol 11, Iss 7, p 597 (2019)
Coxsackievirus-B4 (CV-B4) E2 can persist in the pancreatic ductal-like cells (Panc-1 cell line), which results in an impaired differentiation of these cells into islet-like cell aggregates (ICA). In this study, primary pancreatic ductal cells obtaine
Externí odkaz: https://doaj.org/article/5ad552ebe1894ce687c777e7b4f4b97d
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6
Akademický článek
Automated Digital Image Analysis of Islet Cell Mass Using Nikon's Inverted Eclipse Ti Microscope and Software to Improve Engraftment may Help to Advance the Therapeutic Efficacy and Accessibility of Islet Transplantation across Centers
Autor: Valery Gmyr, Caroline Bonner, Bruno Lukowiak, Valerie Pawlowski, Nathalie Dellaleau, Sandrine Belaich, Isanga Aluka, Ericka Moermann, Julien Thevenet, Rimed Ezzouaoui, Gurvan Queniat, Francois Pattou, Julie Kerr-Conte Ph.D.
Publikováno v: Cell Transplantation, Vol 24 (2015)
Reliable assessment of islet viability, mass, and purity must be met prior to transplanting an islet preparation into patients with type 1 diabetes. The standard method for quantifying human islet preparations is by direct microscopic analysis of dit
Externí odkaz: https://doaj.org/article/376b35dc050e446c94e9a272f5de9fac
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9
Pancreatic islet transplantation under the kidney capsule of mice: model of refinement for molecular and ex-vivo graft analysis
Autor: Valery Gmyr, Julie Kerr-Conte, Nathalie Delalleau, François Pattou, Julien Thevenet
Publikováno v: Laboratory Animals. 55:408-416
Diabetes cell therapy by human islet transplantation can restore an endogenous insulin secretion and normal glycaemic control in type 1 diabetic patients for as long as 10 years post transplantation. Before transplantation, each clinical islet prepar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f8ae2f36ced5c47fa01894db064e799
https://doi.org/10.1177/00236772211004051
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