Výsledky vyhledávání - "VALERIE QUESNIAUX"

Akademický článek

Lung inflammation and interstitial fibrosis by targeted alveolar epithelial type I cell death

Autor: Sandra Carignon, Dorian De Moura Rodrigues, David Gosset, Elodie Culerier, Sarah Huot-Marchand, Florence Savigny, Eric Kaya, Valerie Quesniaux, Aurélie Gombault, Isabelle Couillin, Bernhard Ryffel, Marc Le Bert, Nicolas Riteau

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionThe pathogenesis of chronic lung diseases is multifaceted with a major role of recurrent micro-injuries of the epithelium. While several reports clearly indicated a prominent role for surfactant-producing alveolar epithelial type 2 (AT2)

Externí odkaz: https://doaj.org/article/71754b8105ab4c509c24ac5dfc6cb235

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Akademický článek

Differential Regulation of Allergic Airway Inflammation by Acetylcholine

Autor: Luke B. Roberts, Rita Berkachy, Madina Wane, Dhiren F. Patel, Corinna Schnoeller, Graham M. Lord, Kleoniki Gounaris, Bernhard Ryffel, Valerie Quesniaux, Matthew Darby, William G. C. Horsnell, Murray E. Selkirk

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Acetylcholine (ACh) from neuronal and non-neuronal sources plays an important role in the regulation of immune responses and is associated with the development of several disease pathologies. We have previously demonstrated that group 2 innate lympho

Externí odkaz: https://doaj.org/article/addf3507d9c04285aa718ea4f45c3755

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Akademický článek

Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose

Publikováno v: Cells, Vol 7, Iss 8, p 88 (2018)

Hepatocytes may rupture after a drug overdose, and their intracellular contents act as damage-associated molecular patterns (DAMPs) that lead to additional leukocyte infiltration, amplifying the original injury. Necrosis-derived DNA can be recognized

Externí odkaz: https://doaj.org/article/d9d470a10b70477fb0716d37720427e5

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Akademický článek

GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands.

Autor: Carlos Arterio Sorgi, Stephanie Rose, Nathalie Court, Daniela Carlos, Francisco Wanderley Garcia Paula-Silva, Patricia Aparecida Assis, Fabiani Gai Frantz, Bernhard Ryffel, Valerie Quesniaux, Lúcia Helena Faccioli

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40523 (2012)

In response to pathogen recognition by Toll-like receptors (TLRs) on their cell surface, macrophages release lipid mediators and cytokines that are widely distributed throughout the body and play essential roles in host responses. Granulocyte macroph

Externí odkaz: https://doaj.org/article/b41210b62db249cea9168e3d60405bec

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Akademický článek

All-trans retinoic acid promotes TGF-β-induced Tregs via histone modification but not DNA demethylation on Foxp3 gene locus.

Autor: Ling Lu, Jilin Ma, Zhiyuan Li, Qin Lan, Maogen Chen, Ya Liu, Zanxian Xia, Julie Wang, Yuanping Han, Wei Shi, Valerie Quesniaux, Bernhard Ryffel, David Brand, Bin Li, Zhongmin Liu, Song Guo Zheng

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e24590 (2011)

It has been documented all-trans retinoic acid (atRA) promotes the development of TGF-β-induced CD4(+)Foxp3(+) regulatory T cells (iTreg) that play a vital role in the prevention of autoimmune responses, however, molecular mechanisms involved remain

Externí odkaz: https://doaj.org/article/2a4df82502f64b38b51c679cc75c8d03

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