Zobrazeno 1 - 10
of 2 757
pro vyhledávání: '"V600E mutation"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Patients with BRAF 600E mutated mCRC are associated with specific clinicopathological features and poor prognosis. The relative efficacy of first-line FOLFOXIRI triplet chemotherapy or doublet chemotherapy combined with bevacizuma
Externí odkaz:
https://doaj.org/article/eb74d2392ccd43848b4a98e5e94b2487
Publikováno v:
International Journal of Biomedicine, Vol 14, Iss 3, Pp 524-528 (2024)
Colorectal cancer usually develops from stepwise, multiple mutations involving oncogenes and tumor suppressor genes. Mutations in the BRAF and RAS genes that dysregulate MAPK signaling are strongly associated with human malignancies. Colorectal cance
Externí odkaz:
https://doaj.org/article/7e2dc2fae3a4434494517038c09d91a9
Autor:
Craig Erker, Magimairajan Issai Vanan, Valérie Larouche, Liana Nobre, Chantel Cacciotti, Stéphanie Vairy, Shayna Zelcer, Adam Fleming, Eric Bouffet, Nada Jabado, Geneviève Legault, Samuele Renzi, Tara McKeown, Bruce Crooks, Nirav Thacker, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Sylvia Cheng, Juliette Hukin, Seth Andrew Climans, Mary Jane Lim-Fat, Sarah McKillop, Sarah Lapointe, Mélanie Alves, Julie Bennett, Uri Tabori, Sébastien Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 4022-4029 (2024)
Background: The treatment of BRAF V600E gliomas with BRAF inhibitors (BRAFis) and MEK inhibitors (MEKis) has been increasingly integrated into clinical practice for pediatric low-grade gliomas (PLGGs) and pediatric high-grade gliomas (HGGs). However,
Externí odkaz:
https://doaj.org/article/18a6d0e5930647838048e65c909b0585
Akademický článek
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Autor:
Kensuke Namba, Kazutoshi Isobe, Hiroki Wakabayashi, Ryogo Ohashi, Hiromasa Sakurai, Daiki Sakai, Yusuke Irie, Kenta Takashima, Yu Murakami, Kaichi Kaneko, Nobuyuki Hiruta, Yasuo Matsuzawa
Publikováno v:
Respirology Case Reports, Vol 12, Iss 10, Pp n/a-n/a (2024)
Abstract BRAF is a mediator that activates the mitogen‐activated protein kinase pathway. A mutation in BRAF can cause abnormal pathway activation, leading to cell proliferation. In a Phase II study, the combination therapy of the BRAF inhibitor dab
Externí odkaz:
https://doaj.org/article/9dcef2518b7a436daccff34d260194dd
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Intraglandular dissemination is an important pathological feature of thyroid cancer, yet the biological characteristics of this phenomenon remain relatively underexplored. This paper aims to provide a comprehensive overview of its biological behavior
Externí odkaz:
https://doaj.org/article/74b121e2828b4cb78714253d13cfad4e
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 67, Iss 1, Pp 128-132 (2024)
Background: The incidence of thyroid tumor is increasing, and preoperative diagnosis of hyalinizing trabecular tumor (HTT) is difficult. Aim: To investigate the cytological features of HTT of the thyroid gland. Settings and Design: A retrospective ob
Externí odkaz:
https://doaj.org/article/e24b782e699e4dc8bb50e8e63025c8e8
Autor:
Daisuke Yamai, Yoshifumi Shimada, Hikaru Ozeki, Akio Matsumoto, Kaoru Abe, Yosuke Tajima, Mae Nakano, Hiroshi Ichikawa, Jun Sakata, Toshifumi Wakai
Publikováno v:
Surgical Case Reports, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Background Colorectal cancer (CRC) metastasizes to various organs, while cutaneous metastases are rare. Although there have been several previous reports of axillary cutaneous metastases with other metastases of CRC, there has never been a r
Externí odkaz:
https://doaj.org/article/c42c5b96270848a1a763d449412ce779
Akademický článek
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Akademický článek
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