Zobrazeno 1 - 10
of 70
pro vyhledávání: '"V.V. Barynin"'
Autor:
Guanghui Wu, Mark Shepherd, Syun Ru Yeh, David W. Rice, Robert K. Poole, Jayne Louise Wilson, Svetlana E. Sedelnikova, Changyuan Lu, Paul V. Bernhardt, Tsuyoshi Egawa, V.V. Barynin
Publikováno v:
Journal of Biological Chemistry. 285:12747-12754
The food-borne pathogen Campylobacter jejuni possesses a single-domain globin (Cgb) whose role in detoxifying nitric oxide has been unequivocally demonstrated through genetic and molecular approaches. The x-ray structure of cyanide-bound Cgb has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9e44133cd8bfd4579c9850c103b1e4e
https://doi.org/10.1074/jbc.m109.084509
https://doi.org/10.1074/jbc.m109.084509
Autor:
V.V. Barynin, Karl Wieghardt, Wolfgang Lubitz, Sebastian Sinnecker, Kai-Oliver Schäfer, Robert Bittl, Christian Teutloff, Friedhelm Lendzian
Publikováno v:
Magnetic Resonance in Chemistry. 43:S51-S64
Multi-frequency EPR experiments at 9, 34 and 94 GHz are reported on the antiferromagnetically coupled mixed valence Mn(II)Mn(III) complex of manganese catalase and on several dinuclear manganese model systems. They are compared with similar experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96c548c9b6f5ec6f3fa6231a8ab7ce1
https://doi.org/10.1002/mrc.1685
https://doi.org/10.1002/mrc.1685
Autor:
Steven E. Glynn, David W. Rice, Corné H. Verhees, Daniel de Geus, A. Hartley, David J. Timson, V.V. Barynin, Richard J. Reece, Patrick J. Baker, Svetlana E. Sedelnikova, John van der Oost
Publikováno v:
Journal of Molecular Biology, 337(2), 387-398
Journal of Molecular Biology 337 (2004) 2
Journal of Molecular Biology 337 (2004) 2
Galactokinase (GaIK) catalyses the first step of the Leloir pathway of galactose metabolism, the ATP-dependent phosphorylation of galactose to galactose-l-phosphate. In man, defects in galactose metabolism can result in disorders with severe clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151f28abefffb068f439a582e39744b4
https://doi.org/10.1016/j.jmb.2004.01.043
https://doi.org/10.1016/j.jmb.2004.01.043
Publikováno v:
European Journal of Biochemistry. 270:1102-1116
X-ray crystallography of the nonheme manganese catalase from Lactobacillus plantarum (LPC) [Barynin, V.V., Whittaker, M.M., Antonyuk, S.V., Lamzin, V.S., Harrison, P.M., Artymiuk, P.J. & Whittaker, J.W. (2001) Structure9, 725-738] has revealed the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab8aef7bbb8a3d7bfebb879f7edc069
https://doi.org/10.1046/j.1432-1033.2003.03459.x
https://doi.org/10.1046/j.1432-1033.2003.03459.x
Autor:
V.V. Barynin, Peter J. Artymiuk, Victor S. Lamzin, Mei M. Whittaker, James W. Whittaker, Svetlana V. Antonyuk, Pauline M. Harrison
Publikováno v:
Structure. 9(8):725-738
Background: Catalases are important antioxidant metalloenzymes that catalyze disproportionation of hydrogen peroxide, forming dioxygen and water. Two families of catalases are known, one having a heme cofactor, and the other, a structurally distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4bfc87d5bb3b89e25d3ed627485bbe
Autor:
Patrick J. Baker, Paul Beckett, Graham Catlin, Anthony K. Brown, H. Fiona Rodgers, Shilpa Palan, Wayne Thomas, John M. Clements, Stephen Wood, Sameeh Salama, Mario Lobell, V.V. Barynin, Michael George Hunter, David W. Rice, Mark Whittaker
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:563-570
Peptide deformylase (PDF) is an essential bacterial metalloenzyme which deformylates the N -formylmethionine of newly synthesized polypeptides and as such represents a novel target for antibacterial chemotherapy. To identify novel PDF inhibitors, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fd3ec5af2d4d761a8aa05bac5071e4
https://doi.org/10.1128/aac.45.2.563-570.2001
https://doi.org/10.1128/aac.45.2.563-570.2001
Autor:
Alexander Popov, P. J. Artymyuk, Pauline M. Harrison, P. D. Hempstead, Victor S. Lamzin, V. R. Melik-Adamyan, Svetlana V. Antonyuk, V.V. Barynin
Publikováno v:
Crystallography Reports. 45:105-116
The crystal structures of two forms of the enzyme dimanganese catalase from Thermus Thermophilus (native and inhibited by chloride) were studied by X-ray diffraction analysis at 1.05 and 0.98 A resolution, respectively. The atomic models of the molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e133469e1740f4a641f4d499e8a60a39
https://doi.org/10.1134/1.171145
https://doi.org/10.1134/1.171145
Publikováno v:
Biochemistry. 38:9126-9136
Manganese catalases contain a binuclear manganese cluster that catalyzes the redox dismutation of hydrogen peroxide, interconverting between dimanganese(II) [(2,2)] and dimanganese(III) [(3,3)] oxidation states during turnover. We have investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3a00732f243f2ad0d99eb19220fe6b
https://doi.org/10.1021/bi990499d
https://doi.org/10.1021/bi990499d
Autor:
Amit Taneja, Patrick J. Baker, Greta Galbraith, James M. Bennett, David Brown, Rebecca Ure, Ian Collins, Sachin T. Aiwale, Neil R. Stokes, Joseph M. Sheridan, Anil K. Srivastava, Jeff Errington, Lloyd George Czaplewski, David J. Haydon, Jonathan R. Heal, Pramod K. Chauhan, David W. Rice, Sveta Sedelnikova, V.V. Barynin
Publikováno v:
Science. 321:1673-1675
FtsZ is an essential bacterial guanosine triphosphatase and homolog of mammalian β-tubulin that polymerizes and assembles into a ring to initiate cell division. We have created a class of small synthetic antibacterials, exemplified by PC190723, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c087d2b0be909f5021ad260fae5e4867
https://doi.org/10.1126/science.1159961
https://doi.org/10.1126/science.1159961
The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis
Autor:
A. I. Grebenko, V.V. Barynin, Keith S. Wilson, Vladimir M. Levdikov, Victor S. Lamzin, William Melik-Adamyan
Publikováno v:
Structure. 6:363-376
Background: The biosynthesis of key metabolic components is of major interest to biologists. Studies of de novo purine synthesis are aimed at obtaining a deeper understanding of this central pathway and the development of effective chemotherapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41ac8c3d262fe562a243cede586831f
https://doi.org/10.1016/s0969-2126(98)00038-0
https://doi.org/10.1016/s0969-2126(98)00038-0