Zobrazeno 1 - 10
of 410
pro vyhledávání: '"V.L. Capelozzi"'
Autor:
T.G. Prieto, C.M. Baldavira, J. Machado-Rugolo, E.H.R. Olivieri, E.C.A. da Silva, V.G. Silva, A.M. Ab'Saber, T.Y. Takagaki, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 56 (2023)
Abstract Intratumoral similarities and differences between large-cell neuroendocrine carcinomas (LCNECs) and small-cell lung carcinomas (SCLCs) are determined partially by the Notch signaling pathway, which controls the switch from neuroendocrine to
Externí odkaz:
https://doaj.org/article/31f1c009579d43b09f5eb6204f03eaf3
Autor:
S.M. Fernezlian, C.M. Baldavira, M.L.F. de Souza, C. Farhat, A.F. de Vilhena, J.C.N. Pereira, J.R.M. de Campos, T. Takagaki, M.L. Balancin, A.M. Ab'Saber, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 56 (2023)
Nuclear proliferation marker MIB-1 (Ki-67) immunohistochemistry (IHC) is used to examine tumor cell proliferation. However, the diagnostic or prognostic value of the Ki-67 nuclear staining intensity and location, defined as nuclear gradient (NG), has
Externí odkaz:
https://doaj.org/article/78910457b8ca4822b9fd2169567be683
Autor:
J. Machado-Rugolo, C.M. Baldavira, T.G. Prieto, E.H.R. Olivieri, A.T. Fabro, C.A. Rainho, E.C. Castelli, P.E.M. Ribolla, A.M. Ab'Saber, T. Takagaki, M.A. Nagai, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 56 (2023)
TP53 mutations are frequent in non-small cell lung cancer (NSCLC) and have been associated with poor outcome. The prognostic and predictive relevance of EGFR/TP53 co-mutations in NSCLC is controversial. We analyzed lung tissue specimens from 70 patie
Externí odkaz:
https://doaj.org/article/94249506ec464ca9882769e20d191b00
Autor:
J. Machado-Rugolo, C.M. Baldavira, T.G. Prieto, E.H.R. Olivieri, A.T. Fabro, C.A. Rainho, E.C. Castelli, P.E.M. Ribolla, A.M. Ab'Saber, T. Takagaki, M.A. Nagai, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 55 (2023)
The common epidermal growth factor receptor (EGFR) mutations, such as the L858R point mutation in exon 21 and the in-frame deletional mutation in exon 19, have been definitively associated with response to EGFR-tyrosine kinase inhibitors (EGFR-TKI).
Externí odkaz:
https://doaj.org/article/4b73e94bca05445b8056cab45efd11b1
Autor:
J. Chinoca, D.S. Andrade, A. Mendes, P. De Marchi, T.G. Prieto, C.M. Baldavira, C. Farhat, J.R.M. Martins, H.B. Nader, D.M. Carraro, V.L. Capelozzi, V. de Sá
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 55 (2022)
We evaluated whether hyaluronan (HA) levels in the sputum could be used as a noninvasive tool to predict progressive disease and treatment response, as detected in a computed tomography scan in non-small cell lung cancer (NSCLC) patients. Sputum samp
Externí odkaz:
https://doaj.org/article/63b31aea4c75461483412ddef96d00f9
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 54, Iss 3 (2021)
The vascular network expansion and functioning are important factors affecting normal intra-uterine fetal development. This study addressed the previously reported antiangiogenic potential of beta-2-glycoprotein I (β2GPI) in vivo in the chick embryo
Externí odkaz:
https://doaj.org/article/0b9746e928bd472b9ded6186fe967279
Autor:
V.K. de Sá, T.P. Rocha, AL. Moreira, F.A. Soares, T. Takagaki, L. Carvalho, A.G. Nicholson, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 11, Pp 1039-1047 (2015)
We collected a series of 136 lung/bronchial and 56 matched lung parenchyma tissue samples from patients who underwent lung/bronchial biopsies and presented invasive carcinoma after lung surgery. The lung/bronchial samples included basal cell hyperpla
Externí odkaz:
https://doaj.org/article/da16ef4bb3c946988e5c465255d9f70d
Autor:
M.P. Rangel, L. Antonangelo, M.M.P. Acencio, C.S. Faria, V.K. de Sá, P.S. Leão, C. Farhat, A.T. Fabro, A. Longatto Filho, R.M. Reis, T. Takagaki, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 51, Iss 8 (2018)
Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples. CFL1 was analyz
Externí odkaz:
https://doaj.org/article/2e7ba929075349a8aaea3cc2cecc889a
Autor:
N.B.R. Colombo, M.P. Rangel, V. Martins, M. Hage, D.P. Gelain, D.F. Barbeiro, C.K. Grisolia, E.R. Parra, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 9, Pp 852-862 (2015)
The antioxidant effects of Caryocar brasiliense Camb, commonly known as the pequi fruit, have not been evaluated to determine their protective effects against oxidative damage in lung carcinogenesis. In the present study, we evaluated the role of peq
Externí odkaz:
https://doaj.org/article/02fc2d1fced142b3af85fe30a9343410
Autor:
M.P. Rangel, V.K. de Sá, V. Martins, J.R.M. Martins, E.R. Parra, A. Mendes, P.C. Andrade, R.M. Reis, A. Longatto-Filho, C.Z. Oliveira, T. Takagaki, D.M. Carraro, H.B. Nader, V.L. Capelozzi
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 48, Iss 6, Pp 557-567 (2015)
Hyaluronan (HA) shows promise for detecting cancerous change in pleural effusion and urine. However, there is uncertainty about the localization of HA in tumor tissue and its relationship with different histological types and other components of the
Externí odkaz:
https://doaj.org/article/d07e42ea3dce48908da02dc170336a63