Chronic Toxicity and Oncogenicity Inhalation Study with Vinyl Acetate in the Rat and Mouse

Autor: R. W. Rickard, H. C.Dreef Van Der Meulen, T. C. Cascieri, T. R. Tyler, Matthew S. Bogdanffy, R. B. Beems, M. B. Vinegar, V.J. Feron

Publikováno v: Fundamental and Applied Toxicology, 2, 23, 215-229

Vinyl acetate was evaluated for chronic toxicity and oncogenicity in male and female rats and mice in a 104-week study. Target concentrations were 0, 50, 200, and 600 ppm. The study included interim terminations at approximately 53 and 83 weeks and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4c297e59b2e17f43570c042bc2e9c5
https://doi.org/10.1006/faat.1994.1100

Approach to setting occupational exposure limits for sensory irritants in the Netherlands

Autor: V.J. Feron, J.H.E. Arts, J. Mojet

Publikováno v: American Industrial Hygiene Association Journal, 6, 62, 733-735

This article describes how scientists in the Netherlands set occupational exposure limits (OELs) for sensory irritants. When they tackle this issue, a number of key questions need to be answered. For example, did the studies indeed measure sensory ir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4787a64110fe17f7e65b93c8ae180b
http://resolver.tudelft.nl/uuid:0e3377e3-d50b-466e-a2a6-3c69b45ae65a

Effects of a dietary load of acid or base on changes induced by lactose in rats

Autor: M. Andringa, V.J. Feron, A.P. de Groot, V.M.H. Hollanders, A.J.M. Hagenaars, B.A.R. Lina

Publikováno v: Food and Chemical Toxicology, 1, 33, 1-14

Feeding lactose or other slowly digestible carbohydrates to adult mammals may induce a variety of effects including hyperplasia and neoplasia. The most fundamental effect probably is the increased production in the large intestine of short-chain fatt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2b32abc3a944bd904f778d7b8d536e
https://pubmed.ncbi.nlm.nih.gov/7821870

Nitrate, nitrite and N-nitroso compounds

Autor: Ronald Walker, J.S. Wishnok, V.J. Feron, Gerrit J.A. Speijers, B. Spiegelhalder, P.A. van den Brandt, S.D. Gangolli, Jan H. Koeman, C. Janzowsky

Publikováno v: European journal of pharmacology. Environmental toxicology and pharmacology 292 (1994)
European journal of pharmacology. Environmental toxicology and pharmacology, 292, 1-38
European Journal of Pharmacology, Environmental Toxicology and Pharmacology Section, 292, 1-38

A risk assessment has been made on nitrate, nitrite and N-nitroso compounds encountered in the human diet. Vegetables constitute a major source of nitrate providing over 85% of the average daily human dietary intake. Nitrite and N-nitroso compounds p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7991b31633de5f7b6a8c4206949697
https://research.wur.nl/en/publications/nitrate-nitrite-and-n-nitroso-compounds

One-year time sequence inhalation toxicity study of vinyl chloride in rats. I. Growth, mortality, haematology, clinical chemistry and organ weights

Autor: H.P. Til, V.J. Feron, A. Kruysse

Publikováno v: Toxicology, 1, 13, 25-28

Wistar rats were exposed to atmospheres containing 0 (control) or 5000 ppm vinyl chloride monomer (VCM), 7 h/day, 5 days/week, for a period of 52 weeks. After 4, 13, 26 and 52 weeks each time 10 rats/sex/group were killed and subjected to extensive e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a3f69f8857ea40794ea97b128a8323
https://doi.org/10.1016/s0300-483x(79)80006-2