Zobrazeno 1 - 10
of 15
pro vyhledávání: '"V. Yu. Tanchuk"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 4, Pp 24-31 (2015)
Inhibition of PTP1B by polyhydroxylated fullerenes was studied in silico and in vitro. The enzyme kinetics in the presence of polyhydroxy small gap fullerenes showed that reciprocal value of maximum velocity non-linearly increases with increasing the
Externí odkaz:
https://doaj.org/article/8f3730babb0f42428754499057c15428
Autor:
Volodymyr O. Tanin, V. Yu. Tanchuk
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 13:16-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70ae68f6585c9757389080e84565dc59
https://doi.org/10.24959/ophcj.15.862
https://doi.org/10.24959/ophcj.15.862
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 12:39-42
Calix[4]arene are known to be a promising scaffold for designing inhibitors of protein tyrosine phosphatases. In this work calix[4]arene mono- and bis-α-hydroxymethylphosphonic acids have been tested in vitro for the inhibitory activity against some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53349d7ab711f1062deb577eee148a3e
https://doi.org/10.24959/ophcj.14.782
https://doi.org/10.24959/ophcj.14.782
Autor:
Andriy B. Drapailo, V. Yu. Tanchuk, Lyudmyla A. Kononets, Andriy I. Vovk, Valery P. Kukhar, Vitaly I. Kalchenko
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 66:271-277
Effect of thiacalix[4]arene platform on inhibition of alkaline phosphatase by macrocyclic phosphonate is presented in this article. Using tetrakis(dihydroxyphosphorylmethyl) derivatives we have found that phosphonate inhibitor on thiacalix[4]arene pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a8659fbc4f52890f89191aefb30259
https://doi.org/10.1007/s10847-009-9607-9
https://doi.org/10.1007/s10847-009-9607-9
Autor:
V. V. Shevchenko, A. K. Melnyk, S. M. Kochubey, O. Yu. Bondarenko, R. V. Bugas, Andriy I. Vovk, V. Yu. Tanchuk
Publikováno v:
Biochemistry (Moscow). 72:558-564
A lipophilic nitroxyl radical, 1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl 1-adamantylacetate, has been applied to EPR spin probe study of chloroplasts and subchloroplast fragments of different types. The latter originate from grana and the grana core r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30e49989be88ddbfa07e1c4eef9633c
https://doi.org/10.1134/s0006297907050136
https://doi.org/10.1134/s0006297907050136
Autor:
Alexander I. Luik, V. V. Kovalishin, Igor V. Tetko, V. V. Kholodovich, L. A. Metelitsa, S. A. Poyarkova, V. Yu. Tanchuk
Publikováno v:
Theoretical and Experimental Chemistry. 33:86-89
The application of topological indexes to codify the structures of peptide immunomodulators — analogs of taftsin — and to predict the pharmacological activity of new compounds by the κ-neighbor and neural network methods is described. It is show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0319277d56e8dc8abb196768d0fe9b0
https://doi.org/10.1007/bf02765951
https://doi.org/10.1007/bf02765951
Publikováno v:
Pharmaceutical Chemistry Journal. 30:384-390
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d516bc3a8e3ec1f2ad384e3cc2fe21
https://doi.org/10.1007/bf02219326
https://doi.org/10.1007/bf02219326
Publikováno v:
Theoretical and Experimental Chemistry. 29:45-50
We have obtained an effective correlation equation describing the structure dependence of the activity of a number of hydroxy- and methoxy-substituted flavonoids as cAMP phosphodiesterase inhibitors. We propose an original modification of the Hopfing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3014fae7c459efb4801c22cea109b631
https://doi.org/10.1007/bf00520261
https://doi.org/10.1007/bf00520261
Autor:
Valery P. Kukhar, M. O. Lozinsky, Andriy I. Vovk, V. Yu. Tanchuk, Lyudmyla A. Kononets, A. L. Chuiko, I. V. Murav’eva
Publikováno v:
Bioorganicheskaia khimiia. 34(1)
A series of thioureido derivatives of methylenebisphosphonic acid were synthesized by the reaction of aminomethylenebisphosphonic acid with the corresponding isothiocyanates, and their effect on the activity of alkaline phosphatases from bovine small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0ad9e77cf8e482e48224528b30590d
https://pubmed.ncbi.nlm.nih.gov/18365740
https://pubmed.ncbi.nlm.nih.gov/18365740
Publikováno v:
Theoretical and Experimental Chemistry. 29:84-86
An effective system for predicting the inhibiting activity with respect to 5-lipoxygenase in a series of hydroxamic acids was developed. The bioactivity is predicted based on three selected topological indexes with one variation of the method of k-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c65f3b6bcced44e1bb0c138995ba43
https://doi.org/10.1007/bf00530600
https://doi.org/10.1007/bf00530600