Zobrazeno 1 - 10
of 48
pro vyhledávání: '"V. Willingham"'
Publikováno v:
Radiation Research. 164:474-480
Follow-up measurements of chromosome aberrations in the blood lymphocytes of astronauts were performed by FISH chromosome painting at various intervals from 5 months to more than 5 years after space flight and compared to preflight baseline measureme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc4f5522075bf5f2afef979220c81cf
https://doi.org/10.1667/rr3323.1
https://doi.org/10.1667/rr3323.1
Publikováno v:
Journal of Radiation Research. 43:S129-S132
High-LET radiation is more efficient in producing complex-type chromosome exchanges than sparsely ionizing radiation, and this can potentially be used as a biomarker of radiation quality. To investigate if complex chromosome exchanges are induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9b75a6f3dc5946d54cf8edafc72477
https://doi.org/10.1269/jrr.43.s129
https://doi.org/10.1269/jrr.43.s129
Publikováno v:
Radiation Research. 156:731-738
Cytogenetic analysis of the lymphocytes of astronauts provides a direct measurement of space radiation damage in vivo, which takes into account individual radiosensitivity and considers the influence of microgravity and other stress conditions. Chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878b4e80dbb7da1982b7e27227d528b5
https://doi.org/10.1667/0033-7587(2001)156[0731:caitbl]2.0.co
https://doi.org/10.1667/0033-7587(2001)156[0731:caitbl]2.0.co
Publikováno v:
International Journal of Radiation Biology. 77:175-183
PURPOSE: To investigate how cell-cycle delays in human peripheral lymphocytes affect the expression of complex chromosome damage in metaphase following high- and low-LET radiation exposure. MATERIALS AND METHODS: Whole blood was irradiated in vitro w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfff351ef2166047da8a5a38fee4d4d
https://repo.qst.go.jp/records/42872
https://repo.qst.go.jp/records/42872
Publikováno v:
Radiation Research. 155:57-62
Although biophysical models predict a difference in the ratio of interchromosomal to intrachromosomal interarm exchanges (F ratio) for low- and high-LET radiations, few experimental data support this prediction. However, the F ratios in experiments t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce035a63dd66fad27f43b91c142190c6
https://doi.org/10.1667/0033-7587(2001)155[0057:cofrgf]2.0.co
https://doi.org/10.1667/0033-7587(2001)155[0057:cofrgf]2.0.co
Heavy ions are more efficient in producing complex-type chromosome exchanges than sparsely ionizing radiation, and this can potentially be used as a biomarker of radiation quality. We measured the induction of complex-type chromosomal aberrations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669035cdd32ad590da263ef391093464
http://hdl.handle.net/11588/506279
http://hdl.handle.net/11588/506279
Autor:
Honglu Wu, V. Willingham, Francis A. Cucinotta, Marco Durante, Kerry George, Tracy Chui-hsu Yang
Chromosome aberrations were investigated in human lymphocytes after in vitro exposure to 1H-, 3He-, 12C-, 40Ar-, 28Si-, 56Fe-, or 197Au-ion beams, with LET ranging from approximately 0.4-1393 keV/microm in the dose range of 0.075-3 Gy. Dose-response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed03cf1d6dc22f86f20a098a41e4f9d3
http://hdl.handle.net/11588/141746
http://hdl.handle.net/11588/141746
Publikováno v:
Cytogenetic and genome research. 104(1-4)
Radiation-induced chromosome translocations remain in peripheral blood cells over many years, and can potentially be used to measure retrospective doses or prolonged low-dose rate exposures. However, several recent studies have indicated that some in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701733021c7b3c0acc204c6dac2bcbe1
https://pubmed.ncbi.nlm.nih.gov/15162047
https://pubmed.ncbi.nlm.nih.gov/15162047
Autor:
Honglu Wu, Francis A. Cucinotta, Daila S. Gridley, Kerry George, V. Willingham, Gregory A. Nelson
Publikováno v:
Advances in space research : the official journal of the Committee on Space Research (COSPAR). 30(4)
Although the space radiation environment consists predominantly of energetic protons, astronauts inside a spacecraft are chronically exposed to both primary particles as well as secondary particles that are generated when the primary particles penetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8112fc4923131b93f3a3df8c8ec67cb
https://pubmed.ncbi.nlm.nih.gov/12539753
https://pubmed.ncbi.nlm.nih.gov/12539753
Publikováno v:
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 17
If radiosensitivity is altered in a microgravity environment, it will affect the accuracy of assessing astronauts' risk from exposure to space radiation. To investigate the effects of space flight on radiosensitivity, we exposed a crewmember's blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7046faba509674c475aaccdcfdab3f13
https://pubmed.ncbi.nlm.nih.gov/11776983
https://pubmed.ncbi.nlm.nih.gov/11776983