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Akademický článek

Machine Learning and Health Science Research: Tutorial

Autor: Hunyong Cho, Jane She, Daniel De Marchi, Helal El-Zaatari, Edward L Barnes, Anna R Kahkoska, Michael R Kosorok, Arti V Virkud

Publikováno v: Journal of Medical Internet Research, Vol 26, p e50890 (2024)

Machine learning (ML) has seen impressive growth in health science research due to its capacity for handling complex data to perform a range of tasks, including unsupervised learning, supervised learning, and reinforcement learning. To aid health sci

Externí odkaz: https://doaj.org/article/db7b281df334463880184adbbd156a2f

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Akademický článek

Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis

Autor: Victoria M. Martin, Yamini V. Virkud, Ehud Dahan, Hannah L. Seay, Dvir Itzkovits, Hera Vlamakis, Ramnik Xavier, Wayne G. Shreffler, Qian Yuan, Moran Yassour

Publikováno v: Microbiome, Vol 10, Iss 1, Pp 1-13 (2022)

Abstract Background Complex interactions between the gut microbiome and immune cells in infancy are thought to be part of the pathogenesis for the marked rise in pediatric allergic diseases, particularly food allergies. Food protein-induced allergic

Externí odkaz: https://doaj.org/article/2acfc6803953401b9eb72d82146e0c76

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Akademický článek

Factors influencing age of common allergen introduction in early childhood

Autor: Michael Marget, Yamini V. Virkud, Wayne G. Shreffler, Victoria M. Martin, Qian Yuan

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

ObjectivesWe evaluated factors influencing the timing of allergen introduction in the U.S., including updated peanut introduction guidelines.Study designThe Gastrointestinal Microbiome and Allergic Proctocolitis (GMAP) study is a prospective observat

Externí odkaz: https://doaj.org/article/a9d303e66c314053be71a38fad2eb5a4

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Akademický článek

Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals

Autor: Neal P. Smith, Bert Ruiter, Yamini V. Virkud, Ang A. Tu, Brinda Monian, James J. Moon, J. Christopher Love, Wayne G. Shreffler

Publikováno v: JCI Insight, Vol 6, Iss 13 (2021)

Recent advances in high-throughput T cell receptor (TCR) sequencing have allowed for new insights into the human TCR repertoire. However, methods for capturing antigen-specific repertoires remain an area of development. Here, we describe a potentiall

Externí odkaz: https://doaj.org/article/a91b4c054bd94f21abe24f6110dcf764

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Akademický článek

Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry

Autor: Eveline Y. Wu, Suzanne C. Li, Kathryn S. Torok, Yamini V. Virkud, Robert C. Fuhlbrigge, C. Egla Rabinovich, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry Investigators

Publikováno v: ACR Open Rheumatology, Vol 1, Iss 2, Pp 119-124 (2019)

Abstract Objective Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a m

Externí odkaz: https://doaj.org/article/9a1dc8e108be4eca938efa3c2ffe9425

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Akademický článek

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