Výsledky vyhledávání

Smart detection of microRNAs through fluorescence enhancement on a photonic crystal

Autor: Laura Pasquardini, Francesca Frascella, Cecilia Pederzolli, Lorenzo Lunelli, Cristina Potrich, Emiliano Descrovi, Candido Pirri, V. Vaghi

Publikováno v: Talanta (Oxf.) 150 (2016): 699–704. doi:10.1016/j.talanta.2016.01.002
info:cnr-pdr/source/autori:Pasquardini L, Potrich C, Vaghi V, Lunelli L, Frascella F, Descrovi E, Pirri CF, Pederzolli C/titolo:Smart detection of microRNAs through fluorescence enhancement on a photonic crystal/doi:10.1016%2Fj.talanta.2016.01.002/rivista:Talanta (Oxf.)/anno:2016/pagina_da:699/pagina_a:704/intervallo_pagine:699–704/volume:150

The detection of low abundant biomarkers, such as circulating microRNAs, demands innovative detection methods with increased resolution, sensitivity and specificity. Here, a biofunctional surface was implemented for the selective capture of microRNAs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4093d1866dbd293e7b53e594e50b21a3
https://doi.org/10.1016/j.talanta.2016.01.002

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XPS analysis of genomic DNA adsorbed on PEI-modified surfaces

Autor: Cecilia Pederzolli, Cristina Potrich, Edmondo Battista, Filippo Causa, V. Vaghi, Lia Vanzetti, Laura Pasquardini

Publikováno v: Surface and Interface Analysis. 48:611-615

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b13f1dbee2356500025de1563e5692f6
https://doi.org/10.1002/sia.5932

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Enhancing miRNAs Capture on Polydimethylsiloxane Surface with Nanostructuration

Autor: Patrizia Guida, Laura Pasquardini, V. Vaghi, Ugo Valbusa, Denise Pezzuoli, Luca Repetto, Cristina Potrich, Cecilia Pederzolli, Roberto Lo Savio, Diego Repetto, Lia Vanzetti, Giuseppe Firpo, Elena Angeli

Publikováno v: Journal of Nanomedicine & Nanotechnology.

MicroRNAs (miRNAs) modulate gene expression at post-transcriptional level, while their aberrant presence in circulation correlates with the most common human disorders such as cancer, neuro-degenerative and immune-related diseases. Currently, the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1343e3ba6839008abe577b2dc4cd3f
https://doi.org/10.4172/2157-7439.1000437

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Cell transfer of information via miR-loaded exosomes: a biophysical approach

Autor: Cristina Potrich, V. Vaghi, Lorenzo Lunelli, Cecilia Pederzolli, Laura Pasquardini

Publikováno v: European biophysics journal (2017): 1–9. doi:10.1007/s00249-017-1262-2
info:cnr-pdr/source/autori:Potrich C, Lunelli L, Vaghi V, Pasquardini L, Pederzolli C/titolo:Cell transfer of information via miR-loaded exosomes: a biophysical approach/doi:10.1007%2Fs00249-017-1262-2/rivista:European biophysics journal/anno:2017/pagina_da:1/pagina_a:9/intervallo_pagine:1–9/volume

A new communication route among cells was reported in recent years, via extracellular vesicles and their cargo. Exosomes in particular are attracting increasing interest as privileged mediators of this cell communication route. The exosome-mediated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f2ab8276b1d755567984ba7ca30344

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Bio-functional surfaces for the immunocapture of AGO2-bound microRNAs

Autor: Lorenzo Lunelli, Laura Pasquardini, P. Facci, Cecilia Pederzolli, Lia Vanzetti, Cristina Potrich, V. Vaghi

Publikováno v: Colloids and surfaces. B, Biointerfaces (Online) 146 (2016): 746–753. doi:10.1016/j.colsurfb.2016.06.059
info:cnr-pdr/source/autori:Vaghi V, Potrich C, Lunelli L, Facci P, Pasquardini L, Vanzetti L, Pederzolli C/titolo:Bio-functional surfaces for the immunocapture of AGO2-bound microRNAs/doi:10.1016%2Fj.colsurfb.2016.06.059/rivista:Colloids and surfaces. B, Biointerfaces (Online)/anno:2016/pagina_da:746/pagina_a:753/intervallo_pagine:746–753/volume:146

MicroRNAs (miRNAs) are endogenous, small (18–24 nt), non-coding RNAs that regulate gene expression. Among miRNAs, those bound to the AGO2 protein are the functionally active fraction which mediates the cell regulatory processes and regulate message

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4657430bb364123264f5b313bd7d8dfb
https://pubmed.ncbi.nlm.nih.gov/27449965

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Peering at Brain Polysomes with Atomic Force Microscopy

Autor: Marta Marchioretto, Lorenzo Lunelli, Paola Bernabò, Gabriella Viero, V. Vaghi, Alice Bolner

Publikováno v: Journal of visualized experiments 2016 (2016). doi:10.3791/53851
info:cnr-pdr/source/autori:Lunelli L, Bernabò P, Bolner A, Vaghi V, Marchioretto M, Viero G/titolo:Peering at brain polysomes with atomic force microscopy/doi:10.3791%2F53851/rivista:Journal of visualized experiments/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:2016

The translational machinery, i.e., the polysome or polyribosome, is one of the biggest and most complex cytoplasmic machineries in cells. Polysomes, formed by ribosomes, mRNAs, several proteins and non-coding RNAs, represent integrated platforms wher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595061ce510fafda3d3bcbc8482693eb
https://doi.org/10.3791/53851-v

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On-chip purification and detection of hepatitis C virus RNA from human plasma

Autor: Alessia Lai, Laura Pasquardini, Matteo Cocuzza, Lorenzo Lunelli, Gianguglielmo Zehender, V. Vaghi, Lia Vanzetti, Erika Ebranati, Cecilia Pederzolli, Cristina Potrich, Domenico Bruno Claudio Mombello, Candido Pirri

Publikováno v: Biophysical chemistry
208 (2016): 54–61. doi:10.1016/j.bpc.2015.06.005
info:cnr-pdr/source/autori:Vaghi V.; Potrich C.; Pasquardini L.; Lunelli L.; Vanzetti L.; Ebranati E.; Lai A.; Zehender G.; Mombello D.; Cocuzza M.; Pirri C.F.; Pederzolli C./titolo:On-chip purification and detection of hepatitis C virus RNA from human plasma/doi:10.1016%2Fj.bpc.2015.06.005/rivista:Biophysical chemistry (Print)/anno:2016/pagina_da:54/pagina_a:61/intervallo_pagine:54–61/volume:208

Hepatitis C virus (HCV) is one of the main causes of chronic liver disease worldwide. The diagnosis and monitoring of HCV infection is a crucial need in the clinical management. The conventional diagnostic technologies are challenged when trying to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0f31e3b06385ab991292e04a2daa3e
http://hdl.handle.net/11583/2860932

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OncomiR detection in circulating body fluids: a PDMS microdevice perspective

Autor: Laura Pasquardini, Paola Tiberio, Manuela Ferracin, Veronica De Sanctis, Chiara Ottone, V. Vaghi, Lorenzo Lunelli, Matteo Cocuzza, Cristina Potrich, Gaia Cecilia Santini, Marzia Quaglio, Cecilia Pederzolli, Roberto Bertorelli, Massimo Negrini, Candido Pirri

Publikováno v: Lab on a chip (Online) 14 (2014): 4067–4075. doi:10.1039/c4lc00630e
info:cnr-pdr/source/autori:Potrich C.; Vaghi V.; Lunelli L.; Pasquardini L.; Santini G.C.; Ottone C.; Quaglio M.; Cocuzza M.; Pirri C.F.; Ferracin M.; Negrini M.; Tiberio P.; De Sanctis V.; Bertorelli R.; Pederzolli C./titolo:OncomiR detection in circulating body fluids: A PDMS microdevice perspective/doi:10.1039%2Fc4lc00630e/rivista:Lab on a chip (Online)/anno:2014/pagina_da:4067/pagina_a:4075/intervallo_pagine:4067–4075/volume:14

There is an increasing interest in circulating microRNAs (miRNAs) as potential minimally invasive diagnostic biomarkers in oncology. Considerable efforts are being made in the development of lab-on-a-chip devices for biomedical applications to purify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0491d766895498c4669cf706d95f9193
http://hdl.handle.net/11392/2282021

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