Zobrazeno 1 - 10
of 135
pro vyhledávání: '"V. V. Manko"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 5, Pp 51-60 (2023)
An unhealthy diet often is a cause of obesity, chronic inflammation, and metabolic disruption in multiple organs. However, the direct influence of elevated lipid or sugar consumption on liver, pancreatic, and sperm mitochondria is not well understood
Externí odkaz:
https://doaj.org/article/96223dfb6d4e46b996056e54b8894463
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 4, Pp 14-23 (2020)
Mitochondrial Ca2+ overload may trigger the opening of mitochondrial permeability transition pore (mPTP) and its prolonged activation leads to cell death. ATP synthase is considered as a possible molecular component of the pore. The aim of this study
Externí odkaz:
https://doaj.org/article/f6badd0acf924136b1c9037588ca7f32
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 6, Pp 5-14 (2019)
The ability of the mitochondria to compensate for energy expenditure of cells largely depends on the availability of the oxidative substrates, transported across the intact plasma membrane with molecular carriers of limited affinity. The aim of this
Externí odkaz:
https://doaj.org/article/8aa6aad4c389482497cae596f476fa49
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 3, Pp 34-45 (2019)
The dependence of uncoupled respiratory capacity of intact pancreatic acini on oxidative substrate supply and functional cell state has not yet been studied in detail. In this study, the respiratory responses of isolated pancreatic acini to FCCP were
Externí odkaz:
https://doaj.org/article/959f9132610340dfb676646f869e8297
Autor:
L. G. Babich, S. G. Shlykov, A. M. Kushnarova-Vakal, N. I. Kupynyak, V. V. Manko, V. P. Fomin, S. O. Kosterin
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 3, Pp 32-40 (2018)
The aim of the study was to show the relationships between ionized Ca concentration ([Ca2+]m) in the mitochondria matrix and functional activity of this organelle. [Ca2+]m was determined using the fluorescent probe Fluo-4, AM. Total level of Ca2+ acc
Externí odkaz:
https://doaj.org/article/8add5031a8ed482a86eef510a46eb27a
Publikováno v:
Біологічні студії, Vol 12, Iss 1, Pp 25-34 (2018)
Taurine is sulfur-containing derivative of methionin and cysteine that plays a key role in glucose and lipid metabolism. Taurine regulates antioxidant defense system, membrane potential of mitochondria, and glycolysis. Thus, it might have a serious i
Externí odkaz:
https://doaj.org/article/e69d58f45d634433b76073064083fe93
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 6, Pp 113-121 (2015)
To verify experimentally the model of permeabilized hepatocytes, the degree of cell permeability was assessed using trypan blue and polarographycally determined cell respiration rate upon succinate (0.35 mM) and α-ketoglutarate (1 mM) oxidation. Oxi
Externí odkaz:
https://doaj.org/article/788a9ae166c243529e164c319c57460c
Autor:
R. D. Ostapiv, V. V. Manko
Publikováno v:
Біологічні студії, Vol 9, Iss 2, Pp 59-70 (2015)
Aim of this work was to study the activity of antioxidant defense enzymatic link, glucose-6-phosphate dehydrogenase activity and content of TBA-active products at long term per oral injection of taurine. Male Wistar rats (4.5 months old and with body
Externí odkaz:
https://doaj.org/article/69fbf6f761fe492c8bb8b89763e0bcbf
Autor:
A. B. Kotliarova, V. V. Manko
Publikováno v:
Біологічні студії, Vol 9, Iss 2, Pp 191-206 (2015)
It is known that different Ca2+-transport systems make distinct contribution to the formation of Ca2+-signal in various secretory cells. In recent years there has been a significant increase in interest in study of the lacrimal glands functioning. Ho
Externí odkaz:
https://doaj.org/article/e919c6c050ac45cf86130fed1426d61b
Publikováno v:
Біологічні студії, Vol 9, Iss 2, Pp 71-84 (2015)
The dependence of permeabilized rat hepatocytes respiration rate on oxidation substrates concentration at presence 0.1 and 1 µM Са2+ in the medium and amino sulfonic acid – taurine – effect on this subordination was studied. Experimental anima
Externí odkaz:
https://doaj.org/article/11d1d2cdb4754c11a0e8ac0b2c309d7c