Zobrazeno 1 - 10
of 15
pro vyhledávání: '"V. V. Kushnirov"'
Autor:
O. V. Mitkevich, M. D. Ter-Avanesyan, V. V. Kushnirov, E. R. Surina, A. A. Antipin, S. V. Benevolensky, A. N. Marchenko, E. V. Morozkina
Publikováno v:
Molecular Biology. 43:626-631
Single-stranded DNA aptamers interacting with fibrils of Saccharomyces cerevisiae Sup35p were obtained by the SELEX procedure. The specificity of interactions with Sup35p was investigated for 10 out of 40 selected aptamers. Nine aptamers were found t
Publikováno v:
Molekuliarnaia biologiia. 41(2)
More than 20 human diseases are related to protein misfolding which causes formation of amyloids, fibrillar aggregates of normally soluble proteins. Such diseases are called amyloid diseases or amyloidoses. Of them only prion diseases are transmissib
Autor:
V V, Kushnirov
Publikováno v:
Yeast (Chichester, England). 16(9)
The methods currently used for protein extraction from yeast are either laborious or insufficiently reliable. Here I report a method for protein extraction for electrophoretic analysis that is both easy and reliable. In this method, yeast cells are s
Autor:
M D, Ter-Avanesyan, V V, Kushnirov
Publikováno v:
Biochemistry. Biokhimiia. 64(12)
The data on prions--proteinaceous infectious agents--are briefly summarized. Prions cause several incurable neurodegenerative diseases in mammals, while in lower eukaryotes the prion properties of proteins may be responsible for the inheritance of so
Publikováno v:
Molekuliarnaia biologiia. 32(1)
Publikováno v:
Genetika. 33(5)
The yeast Saccharomyces cerevisiae SUP35 gene that encodes the Sup35p protein homologous to the translation termination eRF3 factor of higher eukaryotes is essential to replication of the nonchromosomally inherited [psi+] determinant. The nonsense su
Publikováno v:
The EMBO journal. 15(12)
The Sup35p protein of yeast Saccharomyces cerevisiae is a homologue of the polypeptide chain release factor 3 (eRF3) of higher eukaryotes. It has been suggested that this protein may adopt a specific self-propagating conformation, similar to mammalia
Publikováno v:
Molekuliarnaia biologiia. 29(4)
The results of studies of yeast cytoplasmically-inherited determinants [psi] and [URE3] are summarized. The existence of tandem amino acid repeats in N-terminal regions of yeast Sup35p protein and in prions of higher eukaryotes is shown. The prion-li
Autor:
V V, Kushnirov, M D, Ter-Avanesian, A R, Dagkesamanskaia, Iu O, Chernov, S G, Inge-Vechtomov, V N, Smirnov
Publikováno v:
Molekuliarnaia biologiia. 24(4)
The sup2 mutations of the yeast Saccharomyces cerevisiae or plasmid-mediated amplification of the wild type SUP2 gene lead to suppression of different types of nonsense mutations. The Sup2 protein includes a C-terminal region homologous to elongation
Autor:
V V, Kushnirov, M D, Ter-Avanesian, V N, Smirnov, Iu O, Chernov, I L, Derkach, O N, Novikova, S G, Inge-Vechtomov, M A, Neĭstat, I I, Tolstorukov
Publikováno v:
Molekuliarnaia biologiia. 24(4)
SUP2(SUP35) is an omnipotent suppressor gene, coding for an EF-1 alpha-like protein factor, involved in the control of translational accuracy in yeast Saccharomyces cerevisiae. A SUP2 gene analogue from yeast Pichia pinus was isolated by complementat