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Akademický článek

Bilayer characteristics of a diether phosphonolipid analog of the major lung surfactant glycerophospholipid dipalmitoyl phosphatidylcholine.

Autor: V Skita, D W Chester, C J Oliver, J G Turcotte, R H Notter

Publikováno v: Journal of Lipid Research, Vol 36, Iss 5, Pp 1116-1127 (1995)

Thermal and lyotropic phase behavior was studied by X-ray diffraction and differential scanning calorimetry for a diether phosphonolipid analog (DEPN-8) of the major lung surfactant glycerophospholipid dipalmitoyl phosphatidylcholine (DPPC). DEPN-8 d

Externí odkaz: https://doaj.org/article/41e0a073f13b44a1b0cf6cab1093fc67

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Alterations in surfactant neutral lipid composition during the development of bleomycin-induced pulmonary fibrosis

Autor: V. Skita, Roger S. Thrall, Charles L. Swendsen

Publikováno v: Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1301:90-96

The purpose of this investigation was to correlate changes in the neutral lipids of pulmonary surfactant with previously observed changes in surfactant phospholipids and lung compliance in the rat model of bleomycin-induced pulmonary fibrosis. Bronch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1019c0ebc8866a231b677471e64bc3f1
https://doi.org/10.1016/0005-2760(96)00023-9

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Bilayer characteristics of a diether phosphonolipid analog of the major lung surfactant glycerophospholipid dipalmitoyl phosphatidylcholine

Autor: Robert H. Notter, Joe G. Turcotte, V. Skita, Carey J. Oliver, David W. Chester

Publikováno v: Journal of Lipid Research, Vol 36, Iss 5, Pp 1116-1127 (1995)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fa9e053b62b06dfd656bf93e26530d
https://doi.org/10.1016/s0022-2275(20)39870-9

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Molecular basis for the inhibition of 1,4-dihydropyridine calcium channel drugs binding to their receptors by a nonspecific site interaction mechanism

Autor: V. Skita, Howard S. Young, L.G. Herbette, R.P. Mason

Publikováno v: Biophysical Journal. 61:1244-1255

The "membrane bilayer" pathway (Rhodes, D. G., J. G. Sarmiento, and L. G. Herbette. 1985. Mol. Pharmacol. 27:612-623.) for 1,4-dihydropyridine calcium channel drug (DHP) binding to receptor sites in cardiac sarcolemmal membranes has been extended to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fced592dcae14a1cb41f8b8191cb8b1
https://doi.org/10.1016/s0006-3495(92)81933-1

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Time-resolved structural studies of the sarcoplasmic reticulum membrane

Autor: Leo G. Herbette, Antonio Scarpa, J.K. Blasie, F. Itshak, D.H. Pierce, V. Skita, D. Pascolini

Publikováno v: Biophysical journal. 49(1)

We have used x-ray and neutron diffraction, coupled with the deuteration of selected membrane molecular components, to determine the time-averaged electron density profiles, to 10 A resolution, of the phospholipid bilayer and of the Ca2" ATPase molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f4a0aaa2ec2451b9edd5120d7bca8b
https://pubmed.ncbi.nlm.nih.gov/19431607

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Rat cerebral cortical synaptoneurosomal membranes. Structure and interactions with imidazobenzodiazepine and 1,4-dihydropyridine calcium channel drugs

Autor: R.P. Mason, Leo G. Herbette, W.J. Shoemaker, Jill Moring, V. Skita, H.C. Hayden, R.M. Salomon

Publikováno v: Biophysical Journal. 58:513-531

Small angle x-ray scattering has been used to investigate the structure of synaptoneurosomal (SNM) membranes from rat cerebral cortex. Electron micrographs of the preparation showed SNM with classical synaptic appositions intact, other vesicles, occa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3beeeb7fb2174c44eebe475d002a0a85
https://doi.org/10.1016/s0006-3495(90)82396-1

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α-Bungarotoxin Binding to Acetylcholine Receptor Membranes Studied by Low Angle X-Ray Diffraction

Autor: V. Skita, Howard S. Young, Leo G. Herbette

The nicotinic acetylcholine receptor (nAChR) carries two binding sites for snake venom neurotoxins. alpha-Bungarotoxin from the Southeast Asian banded krait, Bungarus multicinctus, is a long neurotoxin which competitively blocks the nAChR at the acet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7197be4400c0852fda5fbfcdb24cfd56
https://europepmc.org/articles/PMC1303215/

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Pressure induced hydration dynamics of membranes

Autor: Peter T. C. So, Manfred Kriechbaum, Sol M. Gruner, Shyamsunder Erramilli, A. Polcyn, V. Skita, F. Österberg, Mark W. Tate

Publikováno v: Physical review letters. 72(18)

Pressure-jump initiated time-resolved x-ray diffraction studies of dynamics of the hydration of the hexagonal phase in biological membranes show that (i) the relaxation of the unit cell spacing is non-exponential in time; (ii) the Bragg peaks shift s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb107142d907b4d6760e230dc745d924
https://pubmed.ncbi.nlm.nih.gov/10056030

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Bilayer structure and physical dynamics of the cytochrome b5 dimyristoylphosphatidylcholine interaction

Autor: P. Strittmatter, D.W. Chester, Thomas Mavromoustakos, V. Skita, Howard S. Young

Publikováno v: Scopus-Elsevier

Cytochrome b5 is a microsomal membrane protein which provides reducing potential to delta 5-, delta 6-, and delta 9-fatty acid desaturases through its interaction with cytochrome b5 reductase. Low angle x-ray diffraction has been used to determine th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d15672f799fdc54d0d3eb0924c8a44
https://pubmed.ncbi.nlm.nih.gov/1600082

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