Zobrazeno 1 - 10
of 15
pro vyhledávání: '"V. S. Sirotenko"'
Autor:
V. S. Sirotenko, M. Туan
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 3, Iss 3(10), Pp 64-65 (2015)
We have studied antiplatelet activity of new indole derivants on the experimental model of ADP induced aggregation of platelets in rabbit's plasma in vitro. Seven of the studied substances exceeded comparing drug of acetylsalicylic acid on EK50
Externí odkaz:
https://doaj.org/article/f1ff71cbbd6a4d95961d8d0d1bba028d
Publikováno v:
Journal of Volgograd State Medical University. 19:110-117
On the model of premature aging induced by 30-day dark deprivation (light-dark cycle 24/0 h, artificial illumination 300 Lux), the effect of exogenous melatonin (0.3 mg/kg, 14 days after the cancellation of dark deprivation, intragastric daily in 2 %
Autor:
A. A. Spasov, A. F. Kucheryavenko, K. A. Gaidukova, V. S. Sirotenko, L. A. Smirnova, A. F. Ryabukha, K. A. Kuznetsov, M. V. Velikopol’skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 56:1024-1026
Publikováno v:
Bulletin of Experimental Biology and Medicine. 173:41-45
We studied the effect of antiviral agent riamilovir on ADP-induced platelet aggregation in the absence and presence of LPS. Unlike acetylsalicylic acid (reference drug), riamilovir did not exhibit antiplatelet effect in vitro. However, it markedly su
Autor:
D. V. Mal’tsev, М. О. Skripka, К. A. Gaidukova, Alexander A. Spasov, М. V. Miroshnikov, A. F. Kucheryavenko, К. Т. Sultanova, V. S. Sirotenko
Publikováno v:
Toxicological Review. 1:52-57
The paper presents the results of studying the toxicological profile of a new pharmaceutical substance RU891 with antithrombogenic properties. The minimum toxic dose (TDmin) for RU-891 by peroral administration is 230 mg/kg < TDmin ≤ 460 mg/kg. In
Autor:
N. A. Gurova, F. A. Khaliullin, V. N. Pavlov, A. V. Samorodov, A. A. Spassov, K. A. Gaidukova, V. S. Sirotenko, A. F. Kucheryavenko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:303-306
Autor:
S. G. Tolschina, A. F. Kucheryavenko, Rashida I. Ishmetova, V. A. Babkova, Pavel M. Vassiliev, N. K. Ignatenko, Alexander A. Spasov, Denis A. Babkov, G. L. Rusinov, V. S. Sirotenko
Publikováno v:
Russian Chemical Bulletin. 69:768-773
According to the in silico consensus activity prediction, a series of 3,6-disubstituted 1,2,4,5-tetrazines were synthesized as promising inhibitors of the Maillard reaction. In addition to the studies of antiglycation activity, a comparative in vitro
Autor:
N. G. Panshin, O.N. Zhukovskaya, A.F. Kucheryavenko, A. V. Smirnov, K. A. Gaidukova, A.A. Spasov, V. S. Sirotenko
Publikováno v:
Journal of Volgograd State Medical University. 17:111-115
In this study, the antithrombotic activity of a new chemical compound of a benzimidazole derivative, which has a shielded phenolic substituent in its structure, under the laboratory code RU-1144 was studied, which exhibits high antiplatelet and antio
Autor:
Lyudmila N. Divaeva, V. A. Anisimova, Alexander A. Spasov, Anatolii S. Morkovnik, V. S. Sirotenko, A. F. Kucheryavenko, Tat’yana A. Kuz’menko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 166:747-750
Antithrombotic activity of a novel tricyclic derivative of diazepino[1,2-α]benzimidazole (DAB-15) was examined on the model of arterial thrombosis developed in rats without concomitant pathology and in rats with experimental myocardial infarction. D
Autor:
A A, Spasov, A F, Kucheryavenko, F A, Khaliullin, N A, Gurova, V S, Sirotenko, A V, Samorodov, K A, Gaidukova, V N, Pavlov
Publikováno v:
Bulletin of experimental biology and medicine. 172(3)
We studied the effect of Angipur on the process of experimental thrombosis induced by damage to the carotid artery wall by surface application of 50% ferric chloride (III) solution in rats without comorbidities and with isoproterenol-induced myocardi