Zobrazeno 1 - 10
of 57
pro vyhledávání: '"V. S. Matiichuk"'
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 14, Iss 3, Pp 320-327 (2021)
The problem of finding effective low-toxic anticancer agents is one of the most important in modern medicine and pharmacy. Despite a large selection of anticancer drugs and a variety of mechanisms of their action, the effectiveness of existing drugs
Externí odkaz:
https://doaj.org/article/2546cc6c90554ff1aca329df70fe4731
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 12, Iss 2, Pp 129-134 (2019)
Condensed bicyclic systems with thiazolidine core being annulated to pyridine one occupy prominent place in medicinal chemistry because of their broad spectrum of pharmacological activities. So, the synthesis of new N3 substitutes thiazolo[4,5-b]pyri
Externí odkaz:
https://doaj.org/article/38c595cee4e84b48abcfbeb18b70aa47
Autor:
V. Ya. Horishny, V. S. Matiichuk
Publikováno v:
Russian Journal of Organic Chemistry. 56:1557-1561
The reactions of 2-cyano-3-oxobutanethioamide with ethyl 3-aryl-2-bromopropanoates and dialkyl acetylenedicarboxylates afforded a combinatorial library of new 2-[5-(R-benzyl)-4-oxo-1,3-thtiazolidin-2-ylidene]-3-oxobutanenitrile and [2-(1-cyano-2-oxop
Publikováno v:
Russian Journal of Organic Chemistry. 53:62-65
Ethyl 1-aryl-4-acetyl-5-methyl-1H-pyrazole-3-carboxylates reacted with phenylhydrazine to give the corresponding hydrazones, ethyl 1-aryl-5-methyl-4-[1-(phenylhydrazinylidene)ethyl]-1H-pyrazole-3-carboxylates, which were converted to ethyl 1′-aryl-
Publikováno v:
Russian Journal of Organic Chemistry. 54:799-801
Reaction of 3-aryl-2-chloropropanal with 1-arylsulfonylpropan-2-ones in aqueous ammonia and alcohol under the conditions of Hantzsch pyrrole synthesis led to the selective formation of the products of interrupted Feist-Benary reaction, 2-(R-benzyl)-4
Publikováno v:
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 12, Iss 2, Pp 129-134 (2019)
Condensed bicyclic systems with thiazolidine core being annulated to pyridine one occupy prominent place in medicinal chemistry because of their broad spectrum of pharmacological activities. So, the synthesis of new N3 substitutes thiazolo[4,5-b]pyri
Publikováno v:
Russian Journal of Organic Chemistry. 53:481-483
A convenient procedure was developed for the synthesis of 2-azidobicyclo[2.2.1]heptane whose click reaction with phenylacetylene afforded 1-(bicyclo[2.2.1]heptan-2-yl)-4-phenyl-1H-1,2,3-triazol, and its reactions with ethyl α-bromoacrylate and ethyl
Publikováno v:
Russian Journal of Organic Chemistry. 50:275-279
Reaction of 5-methyl-1-aryl-1H-1,2,3-triazole-4-carbocylic acid chlorides with tryptamine derivatives afforded substituted 1-aryl-N-[2-(1H-indol-3-yl)ethyl]-5-methyl-1H-1,2,3-triazole-4-carboxamides. At heating these compounds in toluene in the prese
Publikováno v:
Russian Journal of Organic Chemistry. 48:519-522
A simple and convenient procedure was proposed for the synthesis of 4-aryl-3-bromobutan-2-ones from methyl vinyl ketone and arenediazonium bromides under Meerwein reaction conditions.
Publikováno v:
Russian Journal of Organic Chemistry. 53:479-480
(4-Amino-1,3-thiazol-2-ylsulfanyl)acetic acids were synthesized by reaction of α-thiocyanatonitriles with sulfanylacetic acid in boiling acetonitrile.