Zobrazeno 1 - 10
of 22
pro vyhledávání: '"V. S. Korsunskii"'
Publikováno v:
Chemistry of Heterocyclic Compounds. 37:490-495
2-Substituted 7-methyl-6-(nitroimidazolyl)thiopurines have been synthesized by the reaction of 2-chloro(phenylamino, cycloalkylamino)-7-methyl-6-thiopurines with 5(4)-halo-4(5)-nitroimidazoles and the reaction of 2,6-dichloro-(6-chloro-2-dimethylamin
Publikováno v:
Chemistry of Heterocyclic Compounds. 37:610-614
The synthesis has been achieved of a series of 9-substituted derivatives of 6-(4-nitroimidazol-5-yl)- and 6-(5-nitroimidazol-4-yl)thiopurines by the reaction of 6-(nitroimidazolyl)thiopurines with alkyl and aralkyl halides, haloalcohols, haloacids an
Publikováno v:
Scopus-Elsevier
Novel N2-alkyl(aryl, dialkyl, cycloalkyl)guanines have been synthesized by treating 2-chloro-7-benzylhypozanthine with amines and debenzylation of the N2-substituted 7-benzylguanine products by means of palladium catalyzed hydrogenation.
Publikováno v:
ChemInform. 22
l-Alkyl(aryl, aralkyl)-substituted 5-chloroimidazoles have been only slightly investigated. Only one representative of this series, l-methyl-5-chlorimidazole (I, see Table i), has been described which was obtained by the Wallach method from N,N'-dime
Publikováno v:
ChemInform. 26
Publikováno v:
ChemInform. 27
Publikováno v:
ChemInform. 33
The synthesis has been achieved of a series of 9-substituted derivatives of 6-(4-nitroimidazol-5-yl)- and 6-(5-nitroimidazol-4-yl)thiopurines by the reaction of 6-(nitroimidazolyl)thiopurines with alkyl and aralkyl halides, haloalcohols, haloacids an
Publikováno v:
Chemistry of Heterocyclic Compounds. 36:74-76
Treatment of 2-chloro-6-thio-7-methylpurine with aniline, piperidine, or morpholine with heating in DMF gives 2-phenylamino(piperidino or morpholino)-6-thio-7-methylpurine. The scheme for the formation of the side products 2,6-dithio-and 2,6-dipiperi
Autor:
L. Yu. Telegin, I. B. Zhukova, P. M. Kochergin, L. S. Tolvinskaya, E. V. Aleksandrova, L. A. Pevnitskii, V. S. Korsunskii, V. G. Pukhal'skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 34:579-581
Azathioprine (Az) is among the currently available effective immunodepressants which is widely used in the treatment of autoimmune and rheumatic diseases [1, 2], idiopathic pulmonary fibrosis [3], clinical transplantation [4 – 6], etc. However, thi
Publikováno v:
Chemistry of Heterocyclic Compounds. 31:337-339