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Propri??t??s pharmacologiques du glim??piride

Autor: V. Profozic, Z. Metelko

Publikováno v: Disease Management and Health Outcomes. 4:29-41

Le glimepiride est un nouveau sulfamide hypoglycemiant appartenant a la classe des sulfonylurees. Il est propose dans le traitement du diabete non insulinodependant (de type 2) lorsque le regime, l’exercice physique et la reduction de la surcharge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e46e95f1a170870ab73368f23f0dbef
https://doi.org/10.2165/00115677-199804001-00003

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Insulin glargine provides greater improvements in glycaemic control vs. intensifying lifestyle management for people with type 2 diabetes treated with OADs and 7-8% A1c levels. The TULIP study

Autor: M. P. Dain, J. F. Blicklé, V. Profozic, M. Piletic, André Grimaldi, S. Jacqueminet, N. Hancu, M. Shestakova

Publikováno v: Diabetes, obesitymetabolism. 11(4)

Aim: To determine whether earlier administration of insulin glargine (glargine) vs. the intensification of lifestyle management (LM) improves glycaemic control in type 2 diabetes patients with A1c 7–8% treated with oral therapy. Methods: TULIP [Tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e29e12f6bb0c38e4bc4e17b4690587e
https://pubmed.ncbi.nlm.nih.gov/19087105

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Effects of a a fixed mixture of 25% insulin lispro and 75% NPL on plasma glucose during and after moderate physical exercise in patients with type 2 diabetes

Autor: J. Boras, Z. Metelko, L. Smircic-Duvnjak, I. Kovacevic, Vineet M. Arora, V. Profozic, Matthias Herz, Barbara N. Campaigne

To compare the plasma glucose (PG) response with a fixed mixture of 25% insulin lispro and 75% NPL (Mix25), prior to a meal and 3 h before exercise, to human insulin 30/70 (30/70) in patients with type 2 diabetes.Thirty-seven patients were treated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755271b58b8888a2e15d2d7a0ff8d6f9
https://doi.org/10.1185/030079902125000615

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Intramuscular injection of insulin lispro or soluble human insulin: pharmacokinetics and glucodynamics in Type 2 diabetes

Autor: Z, Milicevic, V, Profozic, J, Wyatt, S, Ristic, J R, Woodworth, M, Seger, D, Kaliterna, P, Bates, Z, Metelko

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association. 18(7)

The aim of the study was to compare the pharmacokinetics and glucodynamics of insulin lispro and soluble human insulin following intramuscular (i.m.) injection in patients with Type 2 diabetes with secondary failure of sulphonylureas.Single 15-U i.m.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad3e74fb0485315169ae8bab395fddd5
https://pubmed.ncbi.nlm.nih.gov/11553186

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Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment

Autor: C. Lange, Zeljko Metelko, V. Malerczyk, V. Profozic, V. Mrzljak, B. Rosenkranz

Publikováno v: Diabetologia. 39(12)

The pharmacokinetics, efficacy and safety of glimepiride were investigated in a single- and a multiple-dose open study in patients with non-insulin-dependent diabetes mellitus and renal impairment and an initial creatinine clearance above 10 ml/min.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885cb8dbd20876319b558504877a1431
https://pubmed.ncbi.nlm.nih.gov/8960852

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P149 Tester l’utilité de l’insuline glargine initiée précocement au cours du diabète de type 2. Protocole et principales caractéristiques de l’étude TULIP

Autor: M. P. Dain, André Grimaldi, J. F. Blicklé, S. Jacqueminet, N. Hancu, V. Profozic, M. Piletic, M. Shestakova

Publikováno v: Diabetes & Metabolism. 34:H83

Introduction Au cours du diabete de type 2, l'initiation de l'insulinotherapie pour une HbA 1c de 7-8 % permettrait d'atteindre les objectifs glycemiques avec une prise de poids acceptable. Patients et methodes Voir tableau I ci-dessous. 4 patients (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a1ef0ef1fa0ea6b4be86dcda8d4c491
https://doi.org/10.1016/s1262-3636(08)73061-1

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Blood glucose and free insulin levels after the administration of insulin by conventional syringe or jet injector in insulin treated type 2 diabetics

Autor: G. Kerum, V. Profozic, Zdenko Škrabalo, M. Granic

Publikováno v: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 19(9)

UNLABELLED The levels of blood glucose and free insulin were compared in 20 diabetic subjects (type 2) receiving one dose of a combination of fast-acting and intermediary-acting insulins in the morning by means of a needle syringe or a jet injector (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f1505bd5ff2e5dc4d98e9651c4bff8
https://pubmed.ncbi.nlm.nih.gov/3319860

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Effect of Acarbose in Type II Diabetics Treated with Diet Alone, with Diet, and with Sulfonylurea, Diet, and Insulin

Autor: H. Schulz, M. Granić, I. Hillebrand, V. Profozic, M. Koselj, Zdenko Škrabalo

Publikováno v: Acarbose for the Treatment of Diabetes Mellitus ISBN: 9783540191452

Glucosidase inhibition with acarbose, a new therapeutic approach to the treatment of diabetes mellitus, has proven to be effective and well tolerated in over 5000 type I and type II diabetics. In three double-blind, crossover studies with 8-week trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ef1de009fed915eeba2ddd1f682b19a
https://doi.org/10.1007/978-3-642-73583-7_41

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