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Akademický článek

Neutrophil activity in sepsis: a systematic review

Autor: C.B. Resende, I. Borges, W.A. Gonçalves, R. Carneiro, B.M. Rezende, V. Pinho, V. Nobre, M.M. Teixeira

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 53, Iss 12 (2020)

The neutrophil is an important cell in host defense against infections, acting as the first line of microorganism control. However, this cell exhibits dysregulated activity in sepsis and may contribute to the pathogenesis of the disease. This systema

Externí odkaz: https://doaj.org/article/50c3db5253e04184b0c0b9e57749770b

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Akademický článek

Human umbilical cord blood cells in infarcted rats

Autor: V. Pinho-Ribeiro, A.C.V. Maia, J.P S. Werneck-de-Castro, P.F. Oliveira, R.C.S. Goldenberg, A.C. Campos de Carvalho

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 43, Iss 3, Pp 290-296 (2010)

Therapy with bone marrow-derived cells has been used in ischemic patients with reported success. The aim of this study was to determine the therapeutic efficacy of fresh and frozen human umbilical cord blood cells (hUCB) in Wistar rats submitted to p

Externí odkaz: https://doaj.org/article/c03c8000663d4c0080e415cbc4656c3a

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Akademický článek

Soluble Factors from Multipotent Mesenchymal Stromal Cells have Antinecrotic Effect on Cardiomyocytes in Vitro and Improve Cardiac Function in Infarcted Rat Hearts

Autor: P. Fidelis-De-Oliveira, J. P. S. Werneck-De-Castro, V. Pinho-Ribeiro, B. C. M. Shalom, J. H. Nascimento-Silva, R. H. Costa e Souza, I. S. Cruz, R. R. Rangel, R. C. S. Goldenberg, A. C. Campos-De-Carvalho

Publikováno v: Cell Transplantation, Vol 21 (2012)

The mechanisms underlying the functional improvement after injection of multipotent mesenchymal stromal cells (MSCs) in infarcted hearts remain incompletely understood. The aim of this study was to investigate if soluble factors secreted by MSCs prom

Externí odkaz: https://doaj.org/article/20f79e39f25f461390ad00bc58a06114

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Akademický článek

Dissipative optomechanics in high-frequency nanomechanical resonators

Autor: André G. Primo, Pedro V. Pinho, Rodrigo Benevides, Simon Gröblacher, Gustavo S. Wiederhecker, Thiago P. Mayer Alegre

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)

Abstract The coherent transduction of information between microwave and optical domains is a fundamental building block for future quantum networks. A promising way to bridge these widely different frequencies is using high-frequency nanomechanical r

Externí odkaz: https://doaj.org/article/fb92468250984ad7a4bb32a039f8fd89

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Akademický článek

Alemtuzumab as graft-versus-host disease (GVHD) prophylaxis strategy in a developing country: lower rate of acute GVHD, increased risk of cytomegalovirus reactivation

Autor: C.B. Resende, B.M. Rezende, P.T.T. Bernardes, G.M. Teixeira, M.M. Teixeira, V. Pinho, H. Bittencourt

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 50, Iss 2

Acute graft-versus-host disease (aGVHD) and cytomegalovirus reactivation are important complications after allogeneic stem cell transplantation (alloHSCT). Here, we evaluated the impact of treatment with alemtuzumab on the occurrence of aGVHD, cytome

Externí odkaz: https://doaj.org/article/440cae5100564644afa965ef3fe8a19d

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Akademický článek

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Akademický článek

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Akademický článek

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

Autor: Nicola Rath, Jennifer P Morton, Linda Julian, Lena Helbig, Shereen Kadir, Ewan J McGhee, Kurt I Anderson, Gabriela Kalna, Margaret Mullin, Andreia V Pinho, Ilse Rooman, Michael S Samuel, Michael F Olson

Publikováno v: EMBO Molecular Medicine, Vol 9, Iss 2, Pp 198-218 (2016)

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in

Externí odkaz: https://doaj.org/article/965beffc5d8b4fb09500eba6469b356a

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Supplementary Methods, Figures 1 - 9, Tables 1 - 2 from Sirtuin-1 Regulates Acinar-to-Ductal Metaplasia and Supports Cancer Cell Viability in Pancreatic Cancer

Autor: Ilse Rooman, Andrew V. Biankin, Francisco X. Real, Luc Bouwens, Manuel Serrano, Tao Liu, Rob L. Sutherland, Erna Ngwayi Njicop, Emily K. Colvin, Mark J. Cowley, Jianmin Wu, Daniel Herranz, Amanda Mawson, Andreia V. Pinho, Victor J. Sanchez-Arévalo Lobo, Elke Wauters

PDF file - 790K, S Table 1. Primary and secondary antibodies used in immunostaining and Western Blotting experiments S Table 2. Antibodies used for immunoprecipitation experiments S Table 3. Primers used in real time RT-PCR and PCR of the ChIP experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf4e9f289e62cbf35b721f70be85e8f
https://doi.org/10.1158/0008-5472.22398803.v1

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Akademický článek

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