Zobrazeno 1 - 10
of 335
pro vyhledávání: '"V. Pierre"'
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1961 (2024)
Circadian rhythms are endogenous behavioral or physiological cycles that are driven by a daily biological clock that persists in the absence of geophysical or environmental temporal cues. Circadian rhythm-related genes code for clock proteins that ri
Externí odkaz:
https://doaj.org/article/1236235a9bb44ea68799c4da893db23c
Autor:
Liquan Cai, Marco T. Pessoa, Yingnyu Gao, Sidney Strause, Moumita Banerjee, Jiang Tian, Zijian Xie, Sandrine V. Pierre
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3207 (2023)
Na/K-ATPase (NKA)-mediated regulation of Src kinase, which involves defined amino acid sequences of the NKA α1 polypeptide, has emerged as a novel regulatory mechanism of mitochondrial function in metazoans. Mitochondrial metabolism ensures adequate
Externí odkaz:
https://doaj.org/article/cfd5e3f16e254ed384383d7334e2f4e9
Publikováno v:
Cells, Vol 12, Iss 19, p 2367 (2023)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. In metabolic dysfunction-associated steatohepatitis (MASH)-related HCC, cellular redox imbalance from metabolic disturbances leads to dysregulation of the α
Externí odkaz:
https://doaj.org/article/1305760dadd14142a4f021dc058d5817
Autor:
Onyinye Ugonabo, Utibe-Abasi Sunday Udoh, Pradeep Kumar Rajan, Heather Reeves, Christina Arcand, Yuto Nakafuku, Tejas Joshi, Rob Finley, Sandrine V. Pierre, Juan Ramon Sanabria
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1369 (2023)
Metabolic dysfunction-associated steatohepatitis (MASH) is one of the major risk factors for chronic liver disease and hepatocellular carcinoma (HCC). The incidence of MASH in Western countries continues to rise, driving HCC as the third cause of can
Externí odkaz:
https://doaj.org/article/a9f20bfd398a46c8aed3c9e9d0112d55
Autor:
Salomé Rognant, Violetta V. Kravtsova, Elena V. Bouzinova, Elizaveta V. Melnikova, Igor I. Krivoi, Sandrine V. Pierre, Christian Aalkjaer, Thomas A. Jepps, Vladimir V. Matchkov
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Several local Ca2+ events are characterized in smooth muscle cells. We have previously shown that an inhibitor of the Na,K-ATPase, ouabain induces spatially restricted intracellular Ca2+ transients near the plasma membrane, and suggested
Externí odkaz:
https://doaj.org/article/a56547571fdf460383871f5d844faae0
Autor:
Yingnyu Gao, Lilian N D Silva, John D Hurley, Xiaoming Fan, Sandrine V Pierre, Komal Sodhi, Jiang Liu, Joseph I Shapiro, Jiang Tian
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0272117 (2022)
Dilated cardiomyopathy (DCM) is a major cause of cardiac death and heart transplantation. It has been known that black people have a higher incidence of heart failure and related diseases compared to white people. To identify the relationship between
Externí odkaz:
https://doaj.org/article/3ccbd968b04b45bdacbd27220d4117a7
Autor:
Xiaoming Fan, Yingnyu Gao, Xiaolu Zhang, Haroon Y Lughmani, David J Kennedy, Steven T Haller, Sandrine V Pierre, Joseph I Shapiro, Jiang Tian
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244065 (2020)
Tissue fibrosis is a significant health issue associated with organ dysfunction and failure. Increased deposition of collagen and other extracellular matrix (ECM) proteins in the interstitial area is a major process in tissue fibrosis. The microRNA-2
Externí odkaz:
https://doaj.org/article/b41b2d613c18400d916137d23af14644
Autor:
Dan Hu, Samuele Notarbartolo, Tom Croonenborghs, Bonny Patel, Ron Cialic, Tun-Hsiang Yang, Dominik Aschenbrenner, Karin M. Andersson, Marco Gattorno, Minh Pham, Pia Kivisakk, Isabelle V. Pierre, Youjin Lee, Karun Kiani, Maria Bokarewa, Emily Tjon, Nathalie Pochet, Federica Sallusto, Vijay K. Kuchroo, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
CD4+ T cells secreting interleukin-17 (TH17) have diverse functions in modulating autoimmune diseases. Here the authors show via transcriptome analyses that a subset of human TH 17 co-expressing interferon-γ (TH1/17) has a molecular signature simila
Externí odkaz:
https://doaj.org/article/11569c6b2d2b489ab5a6e3fe5796dc19
Autor:
Shreya T. Mukherji, Luca Brambilla, Kailey B. Stuart, Isabella Mayes, Laura C. Kutz, Yiliang Chen, Leandro A. Barbosa, Ibrahim Elmadbouh, Jeff P. McDermott, Steven T. Haller, Michael F. Romero, Manoocher Soleimani, Jiang Liu, Joseph I. Shapiro, Gustavo V. Blanco, Zijian Xie, Sandrine V. Pierre
Publikováno v:
The FASEB Journal. 37
Autor:
Minqi, Huang, Xiaoliang, Wang, Moumita, Banerjee, Shreya T, Mukherji, Laura C, Kutz, Aijie, Zhao, Michael, Sepanski, Chen-Ming, Fan, Guo-Zhang, Zhu, Jiang, Tian, Da-Zhi, Wang, Hua, Zhu, Zi-Jian, Xie, Sandrine V, Pierre, Liquan, Cai
Publikováno v:
Stem Cells
The N-terminal caveolin-binding motif (CBM) in Na/K-ATPase (NKA) α1 subunit is essential for cell signaling and somitogenesis in animals. To further investigate the molecular mechanism, we have generated CBM mutant human-induced pluripotent stem cel