Zobrazeno 1 - 5
of 5
pro vyhledávání: '"V. P. Knowles"'
Autor:
Katherine V Clark-Knowles, Xiaohong He, Karen Jardine, Josée Coulombe, Danielle Dewar-Darch, Annabelle Z Caron, Douglas A Gray, Michael W McBurney
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173002 (2017)
The SIRT1 protein deacetylase is reported to have a remarkably wide spectrum of biological functions affecting such varied processes as aging, cancer, metabolism, neurodegeneration and immunity. However, the SIRT1 literature is also full of contradic
Externí odkaz:
https://doaj.org/article/eea5c16680974a76a38d73f40805ccdc
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112406 (2014)
The protein deacetylase SIRT1 is involved in the regulation of a large number of cellular processes that are thought to be required for cancer initiation and progression. Both SIRT1 activity and tumorigenesis can be influenced by dietary fat and poly
Externí odkaz:
https://doaj.org/article/5507115668004b439c907889e675a823
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82106 (2013)
The protein deacetylase SIRT1 has been implicated in the regulation of a large number of cellular processes that are thought to be required for cancer initiation and progression. There are conflicting data that make it unclear whether Sirt1 functions
Externí odkaz:
https://doaj.org/article/0eba3d34cfb346f3beb5d450b322581b
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8534 (2009)
Epithelial ovarian cancer (EOC) is thought to arise in part from the ovarian surface epithelium (OSE); however, the molecular events underlying this transformation are poorly understood. Germline mutations in the BRCA1 tumor suppressor gene result in
Externí odkaz:
https://doaj.org/article/fee9f50324754beea44aa650da97feb5
Autor:
M. J. Bolton, Sharon S. Yang, C. M. George, H. R. Waters, A. J. Whitehouse, V. P. Knowles, P. A. Collis, A. D. Wilkie, D. H. Carr
Publikováno v:
British Actuarial Journal. 10:101-130
This report, which was sponsored by the Life Board of the Faculty and Institute of Actuaries, was originally published in November 1997.Because it is referred to several times in the paper ‘Reserving, Pricing and Hedging for Policies with Guarantee