Zobrazeno 1 - 10
of 14
pro vyhledávání: '"V. P. Castle"'
Publikováno v:
Pediatric Radiology. 25:S73-S75
Congenital mesoblastic nephroma was originally believed to be a universally benign neoplasm. More recently, aggressive congenital mesoblastic nephromas have been described with local recurrence and/or metastases. We report two patients with documente
Publikováno v:
Anticancer research. 20(1A)
The AKT oncogenes are amplified or AKT kinase activity is constitutively elevated in several types of human malignancy. We sought to determine whether AKT might play a role in the development of resistance to apoptosis induced by chemotherapy. We sho
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 77(1)
Thrombospondin-1 (TSP1) is a multifunctional matrix protein that influences the growth and function of a variety of normal and neoplastic epithelial and mesenchymal cell types. In vivo, TSP1 has shown potent antitumor activity in suppressing tumor ne
Autor:
M G, Dole, M F, Clarke, P, Holman, M, Benedict, J, Lu, R, Jasty, P, Eipers, C B, Thompson, C, Rode, C, Bloch, Nuñez, V P, Castle
Publikováno v:
Cancer research. 56(24)
bcl-x is a member of the bcl-2 family of genes and by alternative splicing gives rise to two distinct mRNAs: bcl-xL and bcl-xS. We have previously investigated the expression of Bcl-x in neuroblastoma (NB) cell lines and have shown that Bcl-xL is exp
Autor:
B L, Shulkin, D M, Wieland, M E, Baro, D R, Ungar, D S, Mitchell, M G, Dole, J B, Rawwas, V P, Castle, J C, Sisson, R J, Hutchinson
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(1)
The goals of this investigation were to characterize the uptake of 11C-hydroxyephedrine (HED) in neuroblastoma and to determine the feasibility and potential advantages of utilizing this compound as a tumor imaging agent.Seven patients with known or
Publikováno v:
The American journal of pathology. 147(6)
Insulin-like growth factor II (IGF-II) acts as an autocrine growth factor for many in vitro tumor cell lines including neuroblastoma. To examine the role of IGF-II in tumor biology we have analyzed a total of 56 primary neuroblastoma tumor samples fo
Publikováno v:
Pediatric radiology. 25
Congenital mesoblastic nephroma was originally believed to be a universally benign neoplasm. More recently, aggressive congenital mesoblastic nephromas have been described with local recurrence and/or metastases. We report two patients with documente
Publikováno v:
Cancer research. 55(12)
bcl-x is a new member of the bcl-2 gene family and is highly expressed in neural tissues. The present study was designed to determine the expression of the bcl-x gene products in neuroblastoma (NB) and their role in the modulation of chemotherapy-ind
Publikováno v:
Cancer research. 54(12)
bcl-2 is the first member of a new class of protooncogenes the products of which inhibit programmed cell death (PCD) or apoptosis. We have previously determined that Bcl-2 is expressed in a significant percentage of untreated primary neuroblastoma (N
Publikováno v:
Cancer. 73(5)
An 8-year-old boy, initially diagnosed with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) (French-American-British [FAB]-L1), relapsed with Ph+ acute myelogenous leukemia (AML) (FAB-M2) 21 months after successful ALL treat