Zobrazeno 1 - 6
of 6
pro vyhledávání: '"V. P. Almazov"'
Publikováno v:
Molecular Biology. 41:863-877
Tumor suppressor p53 is the central component of a system maintaining the genetic stability of animal and human somatic cells. Its gene is inactivated in almost all human cancers, allowing a tumor cell to rapidly accumulate additional mutations and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ea5005f7db3b2313136098294951014
https://doi.org/10.1134/s0026893307060015
https://doi.org/10.1134/s0026893307060015
Publikováno v:
Molecular Biology. 37:102-109
Dominant-negative mutations of the p53 tumor suppressor gene and oligomerization of the mutant and wild-type p53 are considered to be responsible for functional inactivation of the p53 tetramer. Although dominant-negative inactivation of p53 is well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab8a424f73812d8e8405739734f461fc
https://doi.org/10.1023/a:1022393031857
https://doi.org/10.1023/a:1022393031857
Autor:
Boris P. Kopnin, A. A. Morgunkova, Peter M. Chumakov, V. P. Almazov, V. S. Prasolov, V. N. Kalinin
Publikováno v:
Molecular Biology. 36:522-527
A chimeric p53 cDNA was constructed so that the fragment coding for 39 residues of the chicken p53 tetramerization domain replaced the corresponding region of human p53. The chimeric cDNA substantially inhibited the colony-forming ability of transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59bb8ae4447dcb88420da000332498b1
https://doi.org/10.1023/a:1019856528001
https://doi.org/10.1023/a:1019856528001
Publikováno v:
Molekuliarnaia biologiia. 36(4)
A chimeric p53 cDNA was constructed so that the fragment coding for 39 residues of the chicken p53 tetramerization domain replaced the corresponding region of human p53. The chimeric cDNA substantially inhibited the colony-forming ability of transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c97b187e028cd6f186c795f7096eeee3
https://pubmed.ncbi.nlm.nih.gov/12173471
https://pubmed.ncbi.nlm.nih.gov/12173471
Publikováno v:
International Journal of Quantum Chemistry. 16:769-775
Using a spectrokinetic approach the absorption spectra of the short-lived transient products in the enzymatic reaction of the glutamate decarboxylase with natural substrate are determined for the first time. The quantum-chemical calculations of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37d0ce58fccd4c42d9b07b58a8827b89
https://doi.org/10.1002/qua.560160408
https://doi.org/10.1002/qua.560160408
Publikováno v:
Molekuliarnaia biologiia. 19(2)
Interaction of glutamate decarboxylase with its adequate substrate and some quasi-substrates was studied by spectrokinetic, quantum-chemical and some other approaches. It was shown that in the course of decarboxylation an abortive transamination of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::836e01eb93eb73bc35483c6aae34a220
https://pubmed.ncbi.nlm.nih.gov/2860562
https://pubmed.ncbi.nlm.nih.gov/2860562