Zobrazeno 1 - 10
of 48
pro vyhledávání: '"V. O. Chernyshenko"'
Autor:
D. S. Korolova, A. O. Pavlenko, A. Altorjay, S. I. Zhuk, I. V. Us, Y. Tsaryk, A. Suranyi, V. O. Chernyshenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 3, Pp 33-41 (2023)
Thrombotic events are among the most dangerous complications of pregnancy. Therefore, selection of appropriate tests and standardization of techniques used for accurate diagnostics of blood coagulation system state is of great importance. In this pre
Externí odkaz:
https://doaj.org/article/2de3cc3e9ff14260b779de5c50024ab9
Autor:
D. S. Korolova, O. V. Hornytska, V. A. Deyev, V. I. Gryshchuk, T. M. Chernyshenko, T. M. Platonova, V. O. Chernyshenko
Publikováno v:
Biotechnologia Acta, Vol 15, Iss 3, Pp 52-57 (2022)
Aim. Treatment by indirect anticoagulants (vitamin K antagonists) requires a personalized approach for controlling the overall level of prothrombin and the accumulation of its decarboxylated forms. The purpose of this work was to optimize the method
Externí odkaz:
https://doaj.org/article/51962881795a4c1596db40d52be88a0a
Autor:
R. Yu. Marunych, V. O. Chernyshenko, T. M. Chernyshenko, S. O. Kalashnyk, V. O. Menshova, E. M. Makogonenko, A.V. Gudzenko
Publikováno v:
Biotechnologia Acta, Vol 15, Iss 3, Pp 29-34 (2022)
Chelidonium majus is a well-known source of biologically active compounds. Most of them are alkaloids, which are used in researches and for tradition medicine. In this study, we explored the influence of C. majus crude total extract onto blood coagul
Externí odkaz:
https://doaj.org/article/9c912513bc16462db14476c29de25944
Autor:
Ye. M. Stohnii, A. V. Rebriev, O. V. Hornytska, O. Yu. Slominskiy, O. P. Kostiuchenko, K. P. Klymenko, V. O. Chernyshenko
Publikováno v:
Biotechnologia Acta, Vol 14, Iss 6, Pp 37-43 (2021)
Aim. One of the approaches for studying structure and functions of proteins is their limited proteolysis. Proteolytic fragments of macromolecules can preserve the biological activity and can be used for the study of their structural and functional pe
Externí odkaz:
https://doaj.org/article/ec4fb9d2d7e0491e8455f8966e25e6f0
Autor:
D. S. Korolova, Y. M. Stohnii, V. I. Gryshchuk, S. I. Zhuk, I. V. Us, T. M. Chernyshenko, O. P. Kostiuchenko, K. P. Klymenko, O. M. Platonov, O. I. Ivashchenko, V. O. Chernyshenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 2, Pp 62-70 (2021)
Maximum clot firmness (MCF) is the main parameter of thromboelastography (TEG) reflecting the stability of a clot. In this work, we looked for markers that can influence the enhancement of MCF and detected molecular markers and blood clotting param
Externí odkaz:
https://doaj.org/article/17ddacc790fa4af6acfc4d7ac09a246a
Autor:
N. E. Lugovska, I. M. Kolesnikova, Ye. M. Stohnii, V. O. Chernyshenko, A. V. Rebriev, O. P. Kostiuchenko, G .K. Gogolinska, N. A. Dziubliuk, L. D. Varbanets, T. M. Platonova, S. V. Komisarenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 3, Pp 58-70 (2020)
Obtaining new monoclonal antibodies (mAbs) towards fibrin(ogen) and its fragments is an important task for studying mechanisms of blood clot formation, searching for novel antithrombotic agents and developing immunodiagnostics. The aim of the present
Externí odkaz:
https://doaj.org/article/ddc6035f960c4a03aa623a75e99fc06e
Autor:
V. O. Chernyshenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 3, Pp 86-90 (2020)
In memoriam Eduard Lugovskoi and Russell Doolittle we are referring to several episodes of their life and work. Russell Doolittle an American biochemist and his friend and colleague Ukrainian scientist Eduard Lugovskoi, both studied fibrinogen struct
Externí odkaz:
https://doaj.org/article/232efe8e7e8c4c19a0842ef73c90d11c
Autor:
O. S. Tkachenko, Ie. A. Hudz, H. V. Kosiakova, P. P. Klymenko, Y. M. Stohnii, V. A. Didkivskyi, T. M. Chernyshenko, V. O. Chernyshenko, T. M. Platonova
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 60-70 (2020)
In this work we aimed to test the atherosclerotic changes in the aortic wall and pro-coagulant response of the blood coagulation system of spontaneously hypertensive rats (SHR) fed cholesterol-rich diet (CRD) and to study the effect of the anti-infla
Externí odkaz:
https://doaj.org/article/eae996a6760c44e8b24d09c4956a0fdd
Autor:
Y. M. Stohnii, M. V. Ryzhykova, A. V. Rebriev, M. D. Kuchma, R. Y. Marunych, V. O. Chernyshenko, V. A. Shablii, N. M. Lypova, O. Yu. Slominskyi, L. V. Garmanchuk, T. M. Platonova, S. V. Komisarenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 72-84 (2020)
The fibrinogen molecule contains multiple binding motifs for different types of cellular receptors, acting as a molecular link between coagulation and cell adhesion. In this study we generated a truncated form of the fibrinogen molecule lacking the B
Externí odkaz:
https://doaj.org/article/7808a5c3c635467bb8597dd576a7e361
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 1, Pp 92-99 (2019)
Tetracycline is a drug with direct cytotoxic action on the liver, and therefore it is widely used in pharmaceutical studies of therapeutic effectiveness of hepatoprotective preparations. The aim of the present work was to determine the biochemical in
Externí odkaz:
https://doaj.org/article/28ce3bd27f424164a081f354e13ebc4a