Zobrazeno 1 - 10
of 91
pro vyhledávání: '"V. N. PERFILOVA"'
Autor:
V. V. Aleksandrov, S. S. Maskin, N. K. Ermolayeva, V. N. Perfilova, V. V. Matyukhin, M. N. Alimov, D. S. Biriulev, A. Rachid, S. M. Sigaev
Publikováno v:
Неотложная медицинская помощь, Vol 13, Iss 3, Pp 385-398 (2024)
INTRODUCTION. In case of polytrauma, an imbalance occurs between substances produced by the endothelium, the rheological properties of the blood are disrupted, the content of procoagulants increases, the permeability of the vascular wall increases, w
Externí odkaz:
https://doaj.org/article/7529abff7cf24863afdacabb5cdd0077
Autor:
V. N. Perfilova
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 1, Pp 68-82 (2024)
SCIENTIFIC RELEVANCE. The Tox21 (Toxicology in the 21st Century) programme was developed by the US Tox21 Consortium with the aim to replace animal-based toxicity assessments of chemicals with a wide range of in vitro and in silico testing approaches
Externí odkaz:
https://doaj.org/article/18d026ce55954adbac2530fd9ad64345
Publikováno v:
Бюллетень сибирской медицины, Vol 20, Iss 1, Pp 98-104 (2021)
The aim of the study was to assess the changes in physical performance parameters in the progeny of rats with experimental preeclampsia (EP) undergoing early and late pharmacological treatment with gamma- aminobutyric acid (GABA) derivatives.Material
Externí odkaz:
https://doaj.org/article/f503f68a45904dc5ab487beb8e98caa7
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 8, Iss 5, Pp 325-335 (2021)
Maternal preeclampsia can bring about metabolic disorders in the offspring at different stages of ontogeny. Up to date, no ways of preventive pharmacological correction of lipid and carbohydrate metabolism disorders developing in different periods of
Externí odkaz:
https://doaj.org/article/9cbc39ae338a42fe8f1d10b0d49b52e2
Publikováno v:
Бюллетень сибирской медицины, Vol 13, Iss 3, Pp 56-62 (2014)
The aim of investigation was to study the effect of a gamma-aminobutyric acid´s derivative – a compound RGPU-242 – on the mental development of the rat´s offspring with experimental preeclampsia. Famels’s preeclampsia was modeled by replacing
Externí odkaz:
https://doaj.org/article/806943d0b6f848cb8e82af1b216441ae
Autor:
L. A. Smirnova, E. A. Suchkov, A. F. Ryabukha, K. A. Kuznetsov, I. N. Tyurenkov, V. N. Perfilova
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 50-51 (2014)
In the study of excretion of the drug was found that glutaron determined in urine for at least 72 hours of the study. Renal clearance is 123 ml/hour, extrarenal - 34.84 ml/hour by intravenous route of administration. Superiority over extrarenal and r
Externí odkaz:
https://doaj.org/article/6b5cb7bcb6094e1b82fd9f874c5554fe
Autor:
A. A. Nesterova, I. I. Prokofiev, V. N. Perfilova, O. Yu. Evsyukov, M. V. Kustova, I. N. Tyurenkov
Publikováno v:
Bulletin of Siberian Medicine. 22:73-80
Aim. To study pathohistological changes in the myocardium of rats with chronic alcohol intoxication (CAI) after treatment with a new glutamic acid derivative glufimet (compound RSPU-238) and a new gamma-aminobutyric acid (GABA) derivative (compound R
Publikováno v:
I.P. Pavlov Russian Medical Biological Herald. 29:337-346
BACKGROUND: Preeclampsia is a serious complication of pregnancy which augments the risk of cognitive disorders in the offspring at different stages of life. Presently, there are no methods with proven effectiveness for correction of post-hypoxic diso
Autor:
Yu. I. Murinov, S. F. Petrova, V. A. Kataev, V. V. Kataev, S. A. Bashkatov, V. N. Perfilova, E. F. Agletdinov, Sergey P. Ivanov
Publikováno v:
Pharmaceutical Chemistry Journal. 55:531-535
The pharmacokinetic properties of a finished dosage form (FDF) of a combination of lappaconitine, glycyrrhizic acid, and methyluracil (LGM) possessing antiarrhythmic activity were studied. The FDF of LGM upon a single intragastric administration in v
Autor:
V. A. Kataev, E. A. Suchkov, L. A. Smirnova, V. N. Perfilova, K. A. Kuznetsov, G. M. Latypova, M. A. Bychenkova, Ivan N. Tyurenkov, T. A. Popova, A. F. Ryabukha
Publikováno v:
Pharmaceutical Chemistry Journal. 54:1235-1238
Rutin contents in biological samples of blood plasma, cardiomyocytes, and mitochondria of cardiomyocytes in rats after administration of Primula veris L. dense herbal extract were determined using a quantitative HPLC method. The optimum conditions fo