Zobrazeno 1 - 6
of 6
pro vyhledávání: '"V. N. Aldobaev"'
Autor:
S. V. Beliakov, D. O. Shatalov, V. N. Aldobaev, I. S. Ivanov, A. V. Aydakova, D. A. Akhmedova, S. A. Kedik
Publikováno v:
Drug Development and Industrial Pharmacy. 47:1764-1774
Branched oligohexamethyleneguanidine hydrochloride (branched OHMG-HC) possesses high biocidal activity. This study aimed at evaluating the pharmacokinetics of branched OHMG-HC and is mandatory for obtaining permission to conduct clinical studies. The
Publikováno v:
Medicine of Extreme Situations.
Low molecular weight compounds targeting chaperone proteins Hsp90 and Hsp70 have opened up a new avenue in the therapy of neoplasms. In 2020, we tested 3 Hsp70 inhibitors from the class of 4-aminopiperidine derivatives for their antitumor activity on
Publikováno v:
Russian Chemical Bulletin. 67:2098-2102
The synthesis of drug delivery system for pharmaceutical substances, represented by modified shortened single-walled carbon nanotubes, was realized. The synthesis was carried out via covalent grafting of water soluble linker to the graphene surface o
Publikováno v:
Russian Chemical Bulletin. 67:2127-2130
A new efficient method for synthesizing promising heat shock protein inhibitors, N,N-dialkyl- 1-(2-alkylthiopyrimidin-4-yl)piperidin-4-amines, by the reaction of 2-alkyl-4-chlorothiouracils with 4-(N-alkyl-N-methylamino)piperidines was developed. 2-A
Publikováno v:
Toxicological Review. :2-7
Critical parameters of the distributions rates of inhibition of tumor growth (ITG) indices and increasing median survival (IMS), which are adopted in pre-clinical practice for evaluation of the anticancer potential of original substances were accurat
Publikováno v:
Radiochemistry. 58:305-310
Tritium was introduced by the thermal activation method into samples of single-walled carbon nanotubes modified with diaminotriethylene glycol. Chemical linking of the modifier considerably increased the specific radioactivity of the product. The max