Zobrazeno 1 - 10
of 130
pro vyhledávání: '"V. Maurich"'
Publikováno v:
Il Farmaco. 57:207-214
Two known antiherpetic agents, acyclovir and valaciclovir, were coupled with activated poly(ethylene glycol). In vitro drug release studies demonstrated the conjugates to be stable in buffer solutions at pH 7.4 and 5.5, while only PEG–valacyclovir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abb470cf15077b0b1e60d85da605bc6
https://doi.org/10.1016/s0014-827x(01)01193-4
https://doi.org/10.1016/s0014-827x(01)01193-4
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 9:427-431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e818de2d3eb9529bf45d4287aacefb3
https://doi.org/10.1016/0731-7085(91)80168-9
https://doi.org/10.1016/0731-7085(91)80168-9
Autor:
V. Maurich, Sara Drioli, Marina Zacchigna, Gian Maria Bonora, Francesca Cateni, Maurizio Ballico, Gabriella Di Luca
The successful conjugation of active theophylline molecules to two new multifunctional high-molecular weight poly(ethylene glycol) derivatives (MultiPEG) and their pharmacokinetic evaluations are reported. The drug loading was increased up to six tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16011912a1c044e36371b0e923e88e7a
http://hdl.handle.net/11368/1703085
http://hdl.handle.net/11368/1703085
In the present paper two theophylline esters with poly (ethylene glycol) (PEG) and methoxy poly (ethylene glycol) (mPEG) were prepared. Quantitative yields of the pure products were obtained. Unlike the free drug, the drug-polymer conjugates are free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbca8c8d5081031b00764df2aec39b0
https://hdl.handle.net/11368/1703369
https://hdl.handle.net/11368/1703369
Autor:
C. De Micheli, V. Maurich, M. De Amici, T. Gianferrara, M. Carnielli, Enzo Grana, Cinzia Boselli, M. Zacchigna
Publikováno v:
ChemInform. 26
The two pairs of enantiomers of isoxazolidin-3-ones 3 and 4 were synthesized by means of Lipase PS-catalyzed hydrolyses of suitable racemic butyrates. The same butyrates were also employed as key intermediates in the preparation of racemic 3 and 4. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::522244ce3efa83d0de07099218d80c1d
https://doi.org/10.1002/chin.199528240
https://doi.org/10.1002/chin.199528240
Publikováno v:
ChemInform. 27
Summary The metabolism of metoclopramide 1 has been re investigated by HPLC coupled with mass spectrometry. The urine of healthy volunteers showed the presence of a new metabolite 2 derived from the enzymatic oxidation of the primary aromatic amino g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ec859dd9ebf447f3f312bf9f1ac04d
https://doi.org/10.1002/chin.199609104
https://doi.org/10.1002/chin.199609104
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 566:453-459
Many assay procedures have been devised to measure lipolytic activity, but none is without problems. It is for this reason that new methods are still being proposed. In this work we have investigated the use of two esters of p-nitrophenol, the palmit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fd702e330af77c6eb29be37f52c129
https://doi.org/10.1016/0378-4347(91)80262-b
https://doi.org/10.1016/0378-4347(91)80262-b