Zobrazeno 1 - 10
of 247
pro vyhledávání: '"V. Malerczyk"'
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 106:334-336
Treatment of 20 patients with 2 g cefotaxime intravenously and 80 mg gentamicin intramuscularly b.i.d. for various reasons before antibiograms were available showed no recognizable influence on renal function after one week. Patients were without ren
Autor:
G. Apidopoulos, H. Grötsch, G. Haun, P. Crause, M. Hropot, V. Malerczyk, B. Husák, G. Berscheid
Publikováno v:
Thrombosis Research. 66:271-275
Publikováno v:
Biomedizinische Technik/Biomedical Engineering. :129-130
Autor:
E. Klaus, P. Habermann, Brigitte Hušák, V. Malerczyk, P. Crause, H. Grötsch, M. Hropot, G. Apidopoulos, D. Tripier
Publikováno v:
Hämostaseologie. 11:129-131
ZusammenfassungDie Pharmakodynamik und Pharmakokinetik von rekombinantem DNA-Hirudin HBW 023 wurde an Rhesus-Affen in Dosen von 0,1; 0,5; 1,0 und 10,0 mg/kg nach einmaliger intravenöser oder subkutaner Applikation untersucht. HBW 023 zeigte eine dos
Publikováno v:
Diabetologia. 39(12)
The pharmacokinetics, efficacy and safety of glimepiride were investigated in a single- and a multiple-dose open study in patients with non-insulin-dependent diabetes mellitus and renal impairment and an initial creatinine clearance above 10 ml/min.
Publikováno v:
Drug Metabolism and Drug Interactions. 13
After oral administration of a single dose of 200 mg of levofloxacin and 400 mg racemic mixture of ofloxacin to 6 healthy male volunteers in a double-blind, randomised cross-over study, concentrations of the unchanged isomers were determined at vario
Publikováno v:
Drug metabolism and drug interactions. 13(1)
Glimepiride is a new sulphonylurea which is eliminated by the formation of a hydroxy-metabolite (hydroxy-gli) and a carboxymetabolite (carboxy-gli). Animal studies have shown hydroxy-gli to exhibit some hypoglycaemic effects while carboxy-gli does no
Publikováno v:
Drug Metabolism and Drug Interactions. 11
Twelve healthy fasting male volunteers received a single 1.0 mg dose of glimepiride either as an intravenous injection over one minute or as a tablet. Blood and urine samples were taken before drug administration and afterwards for up to 24 hours (bl
Publikováno v:
Drug metabolism and drug interactions. 11(4)
Twelve healthy fasting male volunteers received glimepiride in 1, 2, 4 or 8 mg single oral doses. On the days when glimepiride was taken, the subjects were given a standardised carbohydrate diet (18 bread exchange units) and drank 125 ml of water hou
Publikováno v:
Arzneimittel-Forschung. 43(8)
This study evaluates stimulated insulin production rate (incremental AUC x MCR (metabolic clearance rate) of C-peptide) and blood glucose (BG) response after i.v. administration of glimepiride (Hoe 490, GLI, CAS 93479-97-1) (0.25, 0.50, 0.75, 1.00, 1