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pro vyhledávání: '"V. Maillard"'
Autor:
Hale Tunbak, Rocio Enriquez-Gasca, Christopher H. C. Tie, Poppy A. Gould, Petra Mlcochova, Ravindra K. Gupta, Liane Fernandes, James Holt, Annemarthe G. van der Veen, Evangelos Giampazolias, Kathleen H. Burns, Pierre V. Maillard, Helen M. Rowe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The HUSH complex has been implicated in repressing LINE-1 elements. Here the authors reveal that the complex negatively regulates the type I IFN response in human cells through epigenetic regulation of LINE-1 elements
Externí odkaz:
https://doaj.org/article/ee339e70658d4865897566aa7c7f8a90
Akademický článek
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Akademický článek
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Publikováno v:
Nursing Science Quarterly. 35:332-340
The purpose of this article is to present a Parsesciencing inquiry about the universal humanuniverse living experience of persevering. Six adult historians who engaged in dialogue with the scholar were invited to describe their experiences with the q
Publikováno v:
EMBO J
Recent work reported the existence of a mammalian cell‐autonomous antiviral defence based on RNA interference (RNAi), which relies on the accumulation of virus‐derived small interfering RNAs (vsiRNAs) to guide the degradation of complementary vir
Publikováno v:
Astronomy and Astrophysics-A&A
Astronomy and Astrophysics-A&A, EDP Sciences, 2021, 656, pp.A65. ⟨10.1051/0004-6361/202140865⟩
Astronomy and Astrophysics-A&A, EDP Sciences, 2021, 656, pp.A65. ⟨10.1051/0004-6361/202140865⟩
The atomic-to-molecular hydrogen (H/H2) transition has been extensively studied as it controls the fraction of gas in a molecular state in an interstellar cloud. This fraction is linked to star-formation by the Schmidt-Kennicutt law. While theoretica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677d8ad737be9b6de1aa5ab0aa63098d
https://hal.archives-ouvertes.fr/hal-03465871
https://hal.archives-ouvertes.fr/hal-03465871
Publikováno v:
Le Pharmacien Clinicien. 57:e148
Publikováno v:
Immunity. 54(10)
RNA interference (RNAi) provides antiviral defense in many organisms, including plants, insects, and nematodes. In this issue of Immunity, Fang et al. (2021) utilize designer peptides targeting viral suppressors of RNAi to provide evidence for the re
Autor:
Safia Deddouche, Delphine Goubau, Jan Rehwinkel, Probir Chakravarty, Sharmin Begum, Pierre V Maillard, Annabel Borg, Nik Matthews, Qian Feng, Frank J M van Kuppeveld, Caetano Reis e Sousa
Publikováno v:
eLife, Vol 3 (2014)
The RIG-I-like receptors RIG-I, LGP2, and MDA5 initiate an antiviral response that includes production of type I interferons (IFNs). The nature of the RNAs that trigger MDA5 activation in infected cells remains unclear. Here, we purify and characteri
Externí odkaz:
https://doaj.org/article/663aa2a635a647259cca6a484c5c450c
Autor:
Liane Fernandes, Annemarthe G. van der Veen, Petra Mlcochova, Christopher H.C. Tie, Ravindra K. Gupta, Helen M. Rowe, Rocio Enriquez-Gasca, James Holt, Kathleen H. Burns, Hale Tunbak, Poppy A Gould, Pierre V. Maillard, Evangelos Giampazolias
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 11(1). NATURE PORTFOLIO
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, 11(1). NATURE PORTFOLIO
Funder: UKRI Future Leaders Fellowship (MR/S034498/1)
The Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. We show that HUSH-depletion in human cell lines and primary fibroblasts leads to induction of
The Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. We show that HUSH-depletion in human cell lines and primary fibroblasts leads to induction of