Výsledky vyhledávání - "V. M.G. DeBenedetti"

An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico

Autor: V. M.G. DeBenedetti, S. C. Chia, Judith A. Welsh, William P. Bennett, N. V. Bergasa, H. Cawley, Ylermi Soini, John D. Groopman, L. E. Munoz Espinosa, A. M. DiBisceglie, C. Hansen, E. A. Jones, Catherine Sandoval, I. E. Calderon, Curtis C. Harris, Jia-Sheng Wang, G. E. Trivers

Publikováno v: Carcinogenesis. 17(5)

The p53 tumor suppressor gene is commonly mutated in human hepatocellular carcinoma (HCC). The most frequent mutation in HCC in populations exposed to a high dietary intake of aflatoxin B1 (AFB1) is an AGGarg-->AGTser missense mutation in codon 249 o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f022db5b18ae5397309b3856dfa4bfaf
https://pubmed.ncbi.nlm.nih.gov/8640905

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