Zobrazeno 1 - 1
of 1
pro vyhledávání: '"V. M. Shibilev"'
Autor:
Elena F. Shevtsova, Sergei A. Kuznetsov, Olga N. Zefirova, E. A. Lavrushkina, P. N. Shevtsov, N. A. Zefirov, V. M. Shibilev
Publikováno v:
Russian Chemical Bulletin. 69:558-562
Ester of the tubulin ligand, 2-methoxyestradiol, with two molecules of DNA alkylating agent chlorambucil was proposed as a “triple” mutual prodrug for blocking rapid metabolism of the initial steroid. The target conjugate was synthesized via the