Zobrazeno 1 - 10
of 76
pro vyhledávání: '"V. M. Rzheznikov"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 79(12)
Phytoestrogen genistein can exhibit cytoprotective and antioxidant properties, providing chemopreventive action, and produce cytotoxic effects on some tu- mors. In this work, the cytotoxic, cytoprotective, and antioxidant properties of genistein have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0df264c0b32705cdfc98edc3b7674313
https://pubmed.ncbi.nlm.nih.gov/29791099
https://pubmed.ncbi.nlm.nih.gov/29791099
Autor:
A V, Semeikin, E N, Kareva, T A, Fedotcheva, A S, Lunina, I S, Levina, V M, Rzheznikov, N L, Shimanovskii
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 79(9)
We have studied the effect of new ligands of progesterone receptors, including pregna-D'-pentaran 6-methoxyimino-16a,17a-cyclohexanopregn-4-en-3,20-dio-ne (K1047), 17a-acetoxy-3b-butanoyloxy-6-methylpregna-4,6-dien-20-one (buterol), progesterone (P4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc913f05e062e61621c4f68ec3099c09
https://pubmed.ncbi.nlm.nih.gov/29787667
https://pubmed.ncbi.nlm.nih.gov/29787667
Autor:
T. A. Fedotcheva, N. L. Shimanovskii, V. Yu. Kovtun, A. I. Matyushin, V M Rzheznikov, K. E. Shirokikh
Publikováno v:
Biophysics. 60:957-962
In order to determine the cytotoxic or cytoprotective effect of the synthetic isoflavonoid genistein, we studied its effect on HeLa tumor cells, which contain estrogen alpha receptors and do not contain estrogen beta receptors. It was shown that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a6393e3a517a85533cdd80f386f7294
https://doi.org/10.1134/s000635091506007x
https://doi.org/10.1134/s000635091506007x
Autor:
T A, Fedotcheva, K E, Shirokih, A I, Matyushin, V M, Rzheznikov, V Y, Kovtun, N L, Shimanovskii
Publikováno v:
Biofizika. 60(6)
In this paper we study the effect of synthetic isoflavonoid genistein against cancer HeLa cells, which contain estrogen receptors alpha but not beta, with the aim to determine the cytotoxic or cytoprotective effect of genistein. It is shown that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4252dd7cf8502a1be126b7dc2623a25
https://pubmed.ncbi.nlm.nih.gov/26841510
https://pubmed.ncbi.nlm.nih.gov/26841510
Autor:
T. A. Fedotcheva, Alexey G. Kruglov, N. L. Shimanovskii, Nadezhda I. Fedotcheva, Vera V. Teplova, V M Rzheznikov
Publikováno v:
Biophysics. 57:792-795
Among the targets of steroid hormones are mitochondria, which as the main source of reactive oxygen species (ROS) in the cell play a central role in the development of various pathologies. We studied the effect of progesterone and its synthetic analo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c8cbbec240ac62baaf9cb3b772b7ee1
https://doi.org/10.1134/s0006350912060061
https://doi.org/10.1134/s0006350912060061
Autor:
Z. S. Smirnova, T. A. Titova, B. I. Keda, V. M. Rzheznikov, L. E. Golubovskaya, V. N. Tolkachev, L. P. Sushinina
Publikováno v:
Pharmaceutical Chemistry Journal. 43:601-605
Analogs of 11β-hydroxyestrone and 17α-ethynylestradiol with a cytotoxic bis-(2-chloroethyl)amino-containing substituent were synthesized in two principal steps from the corresponding 11-hydroxysteroids. Introduction of this bulky fragment influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d676ab1442b2a116a7a2a4a283904b
https://doi.org/10.1007/s11094-010-0361-5
https://doi.org/10.1007/s11094-010-0361-5
Autor:
V. N. Luzgina, N. N. Glagolev, L. E. Golubovskaya, V. E. Belyaev, Yu. I. Kiryukhin, V. M. Rzheznikov, A. B. Solov’eva
Publikováno v:
Russian Journal of Physical Chemistry A. 83:2362-2367
It was shown that carrying out the reaction of cholesterol photosensitized oxidation in the presence of porphyrins immobilized on the hydrolyzed copolymer of tetrafluorethylene and H+ form of perfluoro-3,6-dioxo-5-methyl-6-sulfonylfluorideoctene-1 le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f766b9bc03c7906658f895c05289c3
https://doi.org/10.1134/s0036024409130317
https://doi.org/10.1134/s0036024409130317
Autor:
V. M. Rzheznikov, L. E. Golubovskaya, E. E. Mayatskaya, B. I. Keda, L. P. Sushinina, T. A. Titova, V. N. Tolkachev, I. P. Osetrova, Z. S. Smirnova
Publikováno v:
Pharmaceutical Chemistry Journal. 42:111-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79e7194acc22daf5bbb6841855422a81
https://doi.org/10.1007/s11094-008-0080-3
https://doi.org/10.1007/s11094-008-0080-3
Autor:
V. M. Rzheznikov, L. E. Golubovskaya, O. N. Minailova, B. I. Keda, T. I. Ivanenko, V. P. Fedotov, L. P. Sushinina, T. A. Titova, V. N. Tolkachev, I. P. Osetrova, Z. S. Smirnova
Publikováno v:
Pharmaceutical Chemistry Journal. 41:523-526
A series of antitumor compounds combining cytotoxic and estrogen action have been synthesized on the basis of 11β-acyloxyestra-1,3,5(10)-trienes. The corresponding synthons, 11β-hydroxy derivatives of estrone, estradiol, and ethynylestradiol, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::274b7b6995acfa272da72fef7f88f0ee
https://doi.org/10.1007/s11094-008-0004-2
https://doi.org/10.1007/s11094-008-0004-2
Autor:
V. I. Kadentsev, Alexander O. Chizhov, I. D. Nesterov, N. G. Kolotyrkina, N. D. Chuvylkin, O. S. Chizhov, A. A. Kutin, L. E. Golubovskaya, V. M. Rzheznikov
Publikováno v:
European Journal of Mass Spectrometry. 13:207-211
Collision-induced fragmentation of the [M + Na]+ and [M + H]+ ions generated from 3-[4- bis-N,N-(2-chloroethyl)aminophenyl]-acetates in the estrane series under electrospray/ionization was studied. Some regularities in fragmentation pathways dependin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e553c68e9c093660bd0497244df589
https://doi.org/10.1255/ejms.872
https://doi.org/10.1255/ejms.872