Zobrazeno 1 - 10
of 207
pro vyhledávání: '"V. M. Perelmuter"'
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 4, Pp 86-95 (2024)
Background. Integrins, as adhesion molecules, play a key role in the interaction of cells with the basal membrane and intercellular matrix. Numerous studies demonstrate evidence of increased expression of integrins on tumor cells in different types o
Externí odkaz:
https://doaj.org/article/48aff8485a4f4bcca69b5a04604f03cb
Autor:
L. A. Tashireva, A. Yu. Kalinchuk, V. V. Alifanov, E. A. Grigoryeva, E. S. Andriukhova, N. V. Krakhmal, N. O. Popova, V. M. Perelmuter
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 3, Pp 64-72 (2024)
The relationship between the tumour and the microenvironment is of great interest because it may determine the efficacy of new agents aimed at targeting the anti-tumour immune response, such as immune checkpoint inhibitors (ICI s), which have been us
Externí odkaz:
https://doaj.org/article/edd74eeddacb4fa69ecae97583085675
Autor:
O. V. Pankova, V. M. Perelmuter, D. S. Pismenny, A. A. Fedorov, D. M. Loos, E. O. Rodionov, M. V. Zavyalova, S. V. Miller
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 2, Pp 64-71 (2024)
Background. Despite advances in surgical and therapy techniques, non-small cell lung cancer (NSCLC) is one of the most common cancers and the leading cause of cancer-related death. Therefore, it is increasingly important to search for markers that pr
Externí odkaz:
https://doaj.org/article/df9e214661e3455c917bbe0b63003e24
Autor:
V. M. Perelmuter, E. S. Grigoryeva, O. E. Savelieva, V. V. Alifanov, E. S. Andruhova, M. V. Zavyalova, O. D. Bragina, E. Yu. Garbukov, M. E. Menyailo, A. A. Khozyainova, E. V. Denisov, N. V. Cherdyntseva, L. A. Tashireva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Following the discovery of circulating tumor cells (CTCs) in the peripheral blood of cancer patients, CTCs were initially postulated to hold promise as a valuable prognostic tool through liquid biopsy. However, a decade and a half of accumul
Externí odkaz:
https://doaj.org/article/962192a563d74d2db34135b7524661bd
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 1, Pp 87-97 (2024)
Functioning of the PD-1/PD-L1 immune checkpoint in the microenvironment of breast cancer may lead to the tumor escape from the immune response. However, it is unknown how often PD-L1 binds to PD-1 in breast cancer patients, which PD-L1-positive cells
Externí odkaz:
https://doaj.org/article/258d88b2829a4f468024611e05fbdb29
Autor:
M. V. Zavyalova, G. A. Kuznetsov, E. S. Grigoryeva, L. A. Tashireva, D. S. Pismenny, V. M. Perelmuter
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 6, Pp 103-110 (2024)
Background. Distant hematogenous metastasis is the leading cause of tumor-related death from breast cancer. To prevent metastasis, prognostic markers for predicting the risk and location of hematogenous metastases are required. In this regard, it is
Externí odkaz:
https://doaj.org/article/ed166bcb395341848ba5689832233ee0
Autor:
E. O. Rodionov, S. V. Miller, M. M. Tsyganov, L. D. Zhuikova, L. V. Pikalova, O. V. Pankova, V. M. Perelmuter, D. V. Podolko, A. A. Mokh, O. A. Ananina, D. S. Pismenny, V. A. Markovich, D. M. Loos, N. V. Litvyakov
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 6, Pp 45-54 (2024)
Surgery is the standard of care for non-small cell lung cancer (NSCLC). The overall survival rates especially in patients with locally advanced lung cancer are low. The resistance of cancer cells to chemotherapeutic drugs reduces the efficacy of trea
Externí odkaz:
https://doaj.org/article/f266df22513749ba930fcba9fc78fb24
Autor:
M. A. Boldyshevskaya, L. A. Tashireva, E. S. Andryukhova, T. A. Dronova, S. V. Vtorushin, V. M. Perelmuter
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 76-85 (2023)
Cytokeratins (CKs) are well studied as intermediate filaments of the cytoskeleton of epithelial cells, providing specific cell structure and morphology, in particular, apico-basal cell polarization. Meanwhile, a certain specificity of the association
Externí odkaz:
https://doaj.org/article/09c9a0a5af104c618a9797550d56bc1e
Autor:
E. S. Andryukhova, N. V. Krakhmal, L. A. Tashireva, S. V. Vtorushin, M. V. Zavyalova, V. M. Perelmuter
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 5, Pp 180-189 (2023)
lymphangitic carcinomatosis is characterized by the spread of cancer cells through pulmonary lymphatic vessels, which results in secondary interstitial inflammation. The diagnosis of lymphangitic carcinomatosis is challenging due to nonspecific clini
Externí odkaz:
https://doaj.org/article/68440ec8eb624359a7b44366dfe16576
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 3, Pp 66-75 (2023)
Purpose: to evaluate the crowding-induced morphological changes in invasive breast carcinoma and compare the data obtained with the parameters of the tumor progression. Material and Methods. The study group included 107 patients (mean age: 57.2 ± 11
Externí odkaz:
https://doaj.org/article/189f37a8dd8741cf9a232c6d7cad2826