Zobrazeno 1 - 10
of 20
pro vyhledávání: '"V. M. KOLB"'
Publikováno v:
Pharmaceutical research. 2(6)
A series of five fluorescent opioid receptor probes was synthesized by coupling naloxone, oxymorphone or naltrexone with fluorescein or tetramethylrhodamine B. The series was characterized for capacity to displace (3)H-dihydromorphine from rat brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9d51c75fd1fcfd914147d553bdd6add
https://pubmed.ncbi.nlm.nih.gov/24271122
https://pubmed.ncbi.nlm.nih.gov/24271122
Publikováno v:
Pharmaceutical research. 3(1)
Opioid receptor interactions of morphinan-type opioids derivatized at the C-6 carbon were investigated. The compounds, designed as probes for studying opioid receptors, were characterized with regard to affinity for the rat brain mu receptor by compe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ffc96d1f5b97fafb9b5f579465c3e73
https://pubmed.ncbi.nlm.nih.gov/24271359
https://pubmed.ncbi.nlm.nih.gov/24271359
Autor:
V M, Kolb
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 51
Selected works are discussed which clearly demonstrate that mimicking various aspects of the process by which natural products evolved is becoming a powerful tool in contemporary drug discovery. Natural products are an established and rich source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d29b19f6c99e900ee66579cdc864596
https://pubmed.ncbi.nlm.nih.gov/9949862
https://pubmed.ncbi.nlm.nih.gov/9949862
Autor:
V M, Kolb
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4c7417fbe8fa7a3513b91350229c8c8
https://pubmed.ncbi.nlm.nih.gov/9204688
https://pubmed.ncbi.nlm.nih.gov/9204688
Publikováno v:
ResearcherID
Urazole is a five-membered heterocyclic compound which is isosteric with uracil's hydrogen-bonding segment. Urazole reacts spontaneoulsy with ribose (and other aldoses) to give a mixture of four ribosides: alpha and beta pyranosides and furanosides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf600e16f4165a28a9eaf7c3c00ed5c4
https://doi.org/10.1007/bf00175873
https://doi.org/10.1007/bf00175873
Autor:
V M, Kolb
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c02e6b1d5ddf8ec5c5283b442b661fb
https://pubmed.ncbi.nlm.nih.gov/8085012
https://pubmed.ncbi.nlm.nih.gov/8085012
Publikováno v:
Life sciences. 52(15)
The effects were studied of in vivo administration of the new opioid antagonist-estrogen hybrid, naltrexone-estrone azine (EH-NX), on subsequent luteinizing hormone-releasing hormone (LHRH)-stimulated luteinizing hormone (LH) release by the pituitary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8b6054e3a87a389fc083e30741b34b5
https://pubmed.ncbi.nlm.nih.gov/8464327
https://pubmed.ncbi.nlm.nih.gov/8464327
Autor:
V M, Kolb
Publikováno v:
Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ece08b2078bc47a9687a1631f3752402
https://pubmed.ncbi.nlm.nih.gov/1652147
https://pubmed.ncbi.nlm.nih.gov/1652147
Publikováno v:
Journal of the American Chemical Society. 101:3497-3500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff289eac632970bf143d3e108b51d8e6
https://doi.org/10.1021/ja00507a013
https://doi.org/10.1021/ja00507a013
Autor:
V M, Kolb, J P, Snyder
Publikováno v:
NIDA research monograph. 75
A new, comprehensive opiate-receptor model based on calculations of possible events at the molecular level is proposed. Agonist versus antagonist action, ultra long-lasting activity and N-dealkylation accompanying receptor binding are included.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ef2829db6dbbd9a12666b9c9189c206
https://pubmed.ncbi.nlm.nih.gov/2828987
https://pubmed.ncbi.nlm.nih.gov/2828987