Zobrazeno 1 - 10
of 14
pro vyhledávání: '"V. M. GIRIJAVALLABHAN"'
Publikováno v:
Current medicinal chemistry. 8(12)
Farnesyl protein transferase (FPT) inhibition is an interesting and promising approach to non-cytotoxic anticancer therapy. Research in this area has resulted in several orally active compounds that are currently in clinical evaluation. This review f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc4b5eabffd239107c22367272655387
https://pubmed.ncbi.nlm.nih.gov/11562275
https://pubmed.ncbi.nlm.nih.gov/11562275
Publikováno v:
Kirk‐Othmer Encyclopedia of Chemical Technology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccc504ef0a4a8b1177a8e8e8763feb3e
https://doi.org/10.1002/0471238961.1512090707091809.a01
https://doi.org/10.1002/0471238961.1512090707091809.a01
Autor:
M, Liu, M S, Bryant, J, Chen, S, Lee, B, Yaremko, P, Lipari, M, Malkowski, E, Ferrari, L, Nielsen, N, Prioli, J, Dell, D, Sinha, J, Syed, W A, Korfmacher, A A, Nomeir, C C, Lin, L, Wang, A G, Taveras, R J, Doll, F G, Njoroge, A K, Mallams, S, Remiszewski, J J, Catino, V M, Girijavallabhan, W R, Bishop
Publikováno v:
Cancer research. 58(21)
We have been developing a series of nonpeptidic, small molecule farnesyl protein transferase inhibitors that share a common tricyclic nucleus and compete with peptide/protein substrates for binding to farnesyl protein transferase. Here, we report on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b69962ac2e2c1ecfcee5ace6f12ef016
https://pubmed.ncbi.nlm.nih.gov/9810004
https://pubmed.ncbi.nlm.nih.gov/9810004
Autor:
A K, Mallams, R R, Rossman, R J, Doll, V M, Girijavallabhan, A K, Ganguly, J, Petrin, L, Wang, R, Patton, W R, Bishop, D M, Carr, P, Kirschmeier, J J, Catino, M S, Bryant, K J, Chen, W A, Korfmacher, C, Nardo, S, Wang, A A, Nomeir, C C, Lin, Z, Li, J, Chen, S, Lee, J, Dell, P, Lipari, M, Liu
Publikováno v:
Journal of medicinal chemistry. 41(6)
The synthesis of a variety of novel 4-amido, 4-carbamoyl and 4-carboxamido derivatives of 1-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl) piperazine to explore the SAR of this series of FPT inhibitors is described. This resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c560189bf987b069c16e67c5dcf8e714
https://pubmed.ncbi.nlm.nih.gov/9526562
https://pubmed.ncbi.nlm.nih.gov/9526562
Autor:
Patrick Pinto, Sue-Ing Lin, R Rizi, P. D. Jeffrey, Stuart W. McCombie, A. K. Ganguly, V. M. Girijavallabhan
Publikováno v:
Journal of Antimicrobial Chemotherapy. 9:1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5245347af61f4db491df6b48133e7649
https://doi.org/10.1093/jac/9.suppl_c.1
https://doi.org/10.1093/jac/9.suppl_c.1
Publikováno v:
Chemischer Informationsdienst. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::222e01a25eeeb62ae4cab2e64c032208
https://doi.org/10.1002/chin.198201333
https://doi.org/10.1002/chin.198201333
Autor:
V. M. Girijavallabhan, A. K. Ganguly
Publikováno v:
ChemInform. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d48aec37749c3b8f5310aec6d6b7a5f
https://doi.org/10.1002/chin.198932210
https://doi.org/10.1002/chin.198932210
Publikováno v:
Chemischer Informationsdienst. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16dd8ce8ce2f4d0e1733740bc5f9f9d7
https://doi.org/10.1002/chin.198349355
https://doi.org/10.1002/chin.198349355
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b1334971ee16ee2bd06e0123146fbcd
https://pubmed.ncbi.nlm.nih.gov/2898355
https://pubmed.ncbi.nlm.nih.gov/2898355