Zobrazeno 1 - 10
of 235
pro vyhledávání: '"V. M. GIRIJAVALLABHAN"'
Publikováno v:
Current medicinal chemistry. 8(12)
Farnesyl protein transferase (FPT) inhibition is an interesting and promising approach to non-cytotoxic anticancer therapy. Research in this area has resulted in several orally active compounds that are currently in clinical evaluation. This review f
Publikováno v:
Kirk‐Othmer Encyclopedia of Chemical Technology.
Autor:
M, Liu, M S, Bryant, J, Chen, S, Lee, B, Yaremko, P, Lipari, M, Malkowski, E, Ferrari, L, Nielsen, N, Prioli, J, Dell, D, Sinha, J, Syed, W A, Korfmacher, A A, Nomeir, C C, Lin, L, Wang, A G, Taveras, R J, Doll, F G, Njoroge, A K, Mallams, S, Remiszewski, J J, Catino, V M, Girijavallabhan, W R, Bishop
Publikováno v:
Cancer research. 58(21)
We have been developing a series of nonpeptidic, small molecule farnesyl protein transferase inhibitors that share a common tricyclic nucleus and compete with peptide/protein substrates for binding to farnesyl protein transferase. Here, we report on
Autor:
A K, Mallams, R R, Rossman, R J, Doll, V M, Girijavallabhan, A K, Ganguly, J, Petrin, L, Wang, R, Patton, W R, Bishop, D M, Carr, P, Kirschmeier, J J, Catino, M S, Bryant, K J, Chen, W A, Korfmacher, C, Nardo, S, Wang, A A, Nomeir, C C, Lin, Z, Li, J, Chen, S, Lee, J, Dell, P, Lipari, M, Liu
Publikováno v:
Journal of medicinal chemistry. 41(6)
The synthesis of a variety of novel 4-amido, 4-carbamoyl and 4-carboxamido derivatives of 1-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl) piperazine to explore the SAR of this series of FPT inhibitors is described. This resulted
Autor:
Ravindra, Sundaresan1 (AUTHOR), Natarajan, Kannan1 (AUTHOR), Padma Priya, Vetrivel R.1 (AUTHOR), Kataria, Ramesh2 (AUTHOR), Nandi, Ganesh Chandra1 (AUTHOR) ganeshnandi@gmail.com
Publikováno v:
Chemistry - A European Journal. 12/22/2023, Vol. 29 Issue 72, p1-5. 5p.
Autor:
Hang Chen1, Yang Zhou1, Panpan Lei1, Haifeng Wang2, Qiongjiao Yan2, Properzi, Roberta3, Wei Wang2 wang520520wei@163.com, Linhai Jing1 jlhhxg@cwnu.edu.cn, Fener Chen2,4,5 rfchen@fudan.edu.cn
Publikováno v:
Green Synthesis & Catalysis. Nov2023, Vol. 4 Issue 4, p350-354. 5p.
Autor:
Patrick Pinto, Sue-Ing Lin, R Rizi, P. D. Jeffrey, Stuart W. McCombie, A. K. Ganguly, V. M. Girijavallabhan
Publikováno v:
Journal of Antimicrobial Chemotherapy. 9:1-6
Publikováno v:
Chemischer Informationsdienst. 13
Autor:
V. M. Girijavallabhan, A. K. Ganguly
Publikováno v:
ChemInform. 20