Zobrazeno 1 - 10
of 64
pro vyhledávání: '"V. M. Bukhman"'
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 7-8, Pp 14-17 (2020)
Ophiocordyceps sinensis and Cordyceps militaris metabolites showed a high potential in the treatment of tumors as well as some other diseases. Antitumor properties of O.sinensis and C.militaris submerged mycelium were investigated. It was found that
Externí odkaz:
https://doaj.org/article/84e4cb3eb2a446959475d92510b327fc
Autor:
O. I. Konyaevа, V. A. Chaley, N. Yu. Kulbachevskaya, T. V. Abramova, N. P. Ermakova, I. B. Merkulova, V. M. Bukhman
Publikováno v:
Russian Journal of Biotherapy. 17:76-82
In accordance with Russian Federal program of import substitution of foreign medicines quality of Russian drugs in the N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, played vincristine-RONC (VC-RONC), which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac60536b4349e00baafa5e98e28ff2c
https://doi.org/10.17650/1726-9784-2018-17-1-76-82
https://doi.org/10.17650/1726-9784-2018-17-1-76-82
Autor:
G. L. Levit, M. P. Kiseleva, V. P. Krasnov, Vera V. Musiyak, N. S. Saprykina, L. M. Borisova, Z. S. Shprakh, M. A. Baryshnikova, V. M. Bukhman
Publikováno v:
Russian Journal of Biotherapy. 16:55-60
Background. Drugs of nitrosourea class are actively and successfully administered in oncology practice. However, at present, the search for new antitumor agents of this class is very urgent. Objective: to examine in vivo antitumor activity of ormusti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2304ae5376ba9cdbc0eaa2f28f6bb6a2
https://doi.org/10.17650/1726-9784-2017-16-4-55-60
https://doi.org/10.17650/1726-9784-2017-16-4-55-60
Autor:
L. M. Michailova, V. M. Bukhman, N. Y. Kulbachevskaya, O. I. Konyaeva, N. P. Ermakova, S. S. Trofimov
Publikováno v:
Russian Journal of Biotherapy. 16:42-49
Introduction. Neurotoxicity is one of the specific systemic complications of anticancer chemotherapy. Detection in experimental animals complications of psychotropic or neurotropic action of the new drug is one of the most difficult challenges of pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2974c28a4850b1c8894eb996a76629
https://doi.org/10.17650/1726-9784-2017-16-2-42-49
https://doi.org/10.17650/1726-9784-2017-16-2-42-49
Publikováno v:
Russian Journal of Biotherapy. 16:12-23
Dendritic cells play key role during tumorigenesis and immune response to it. They are able to uptake and present antigens to T cells, resulting in specific T cell mediated immune response. Furthermore, interaction between dendritic cells and other t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a6f3445020c992bd1f227caf185ea0
https://doi.org/10.17650/1726-9784-2017-16-1-12-23
https://doi.org/10.17650/1726-9784-2017-16-1-12-23
Publikováno v:
Russian Journal of Biotherapy. 15:25-33
Immune system plays a crucial role in tumor growth process. It exerts cancer surveillance function via innate and adaptive immune mechanisms, nonetheless tumor may exploit various immune cells to escape specific immune response. Dendritic cells are t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55d79662f83cddf2b8aa21eaab289cc4
https://doi.org/10.17650/1726-9784-2016-15-4-25-33
https://doi.org/10.17650/1726-9784-2016-15-4-25-33
Autor:
V. A. Chaley, A. A. Nikolina, N. Ju. Kul’Bachevskaya, N. P. Ermakova, V. M. Bukhman, O. I. Konjaeva
Publikováno v:
Russian Journal of Biotherapy. 15:62-69
Background. In N.N. Blokhin Russian Cancer Research Center has been developed injectable dosage form based on the substance of indolocarbazole derivative LCS-1208, studied its antitumor activity and mechanism of antitumor effect, which was the basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::710ea3b2772289b9797bbca76bc68079
https://doi.org/10.17650/1726-9784-2016-15-3-62-69
https://doi.org/10.17650/1726-9784-2016-15-3-62-69
Autor:
M. M. Davydov, Z. S. Smirnova, L. M. Borisova, Galina L. Levit, M. P. Kiseleva, Victor P. Krasnov, Z. S. Shprakh, V. M. Bukhman, Vera V. Musiyak, M. A. Baryshnikova, N. S. Saprykina
Publikováno v:
Russian Journal of Biotherapy. 15:24-31
Objective: Evaluation of antitumor activity of a novel alkylnitrosoureas derivative Ormustine (an alkylnitrosocarbamoyl L-ornithine) in mouse lymphoid leukemia models. Materials and methods Antitumor activity of Ormustine has been evaluated in B6D2F1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47349686f477caa4b26ba056d883f81f
https://doi.org/10.17650/1726-9784-2016-15-2-24-31
https://doi.org/10.17650/1726-9784-2016-15-2-24-31
Autor:
V. M. Bukhman, O. I. Konjaeva, N. P. Ermakova, V. A. Chalej, A. A. Nikolina, N. Ju. Kul'bachevskaja
Publikováno v:
Russian Journal of Biotherapy. 14:59-64
The research has been devoted to the study of acute toxicity of preparation based on derivative of indolocarba- zole - LCS-1208 in mice of both sexes and in rats of both sexes at intravenous and intraperitoneal administration of the drug. In the expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ec02648ad52f6cbe73f1543d4eb31f
https://doi.org/10.17650/1726-9784-2015-14-4-59-64
https://doi.org/10.17650/1726-9784-2015-14-4-59-64
Autor:
V. M. Bukhman, N. Yu. Kulbachevskaya, O. I. Konyaeva, V. A. Chaley, A. A. Nikolina, N. P. Ermakova
Publikováno v:
Russian Journal of Biotherapy. 14:65-72
The paper presents the results of the study of «acute» toxicity and some results of the study of «subchronic» toxicity of Ormustin, a new anticancer drug belonging to nitrosourea class, in small laboratory animals. In the experiments the laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c2c1e33780c9621575c63e14f7d68c3
https://doi.org/10.17650/1726-9784-2015-14-4-65-72
https://doi.org/10.17650/1726-9784-2015-14-4-65-72