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Publikováno v:
Xenobiotica. 34:335-344
1. The aim was to identify the individual human cytochrome P450 (CYP) enzymes responsible for the in vitro N-demethylation of hydromorphone and to determine the potential effect of the inhibition of this metabolic pathway on the formation of other hy
Autor:
S A Benetton, V M Borges, Maria Inês Rocha Miritello Santoro, Erika Rosa Maria Kedor-Hackmann
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 21:3215-3221
The determination of rifampin in the presence of its acidinduced degradation products by reversed-phase high performance liquid chromatography is described. The method was validated as stability-indicating by forced decomposition of rifampin in acid
Autor:
Maria Inês Rocha Miritello Santoro, S A Benetton, V M Borges, Erika Rosa Maria Kedor-Hackmann
Publikováno v:
Talanta. 47:639-643
Two methods are described for the determination of rifampicin and isoniazid in mixtures by visible spectrophotometry and first-derivative ultraviolet spectrophotometry. The absorbance at 475 nm in buffer solution pH 7.4 was employed to determine rifa
Publikováno v:
Bollettino chimico farmaceutico. 131(6)
Shelf-lives of liquid pharmaceutical preparations (injectable and oral solution) containing phenobarbital sodium, commercially available in Brazil, were predicted by accelerated stability test using isothermal method (at 37 degrees C, 50 degrees C an
Publikováno v:
Parasitology Research; Jan2005, Vol. 95 Issue 2, p90-96, 19p