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The evolving role of external beam radiotherapy in localized prostate cancer

Autor: Carlo Greco, V. Louro, Beatriz Nunes, N. Pimentel, Justyna Kociolek, Zvi Fuks, Ana Luisa Vasconcelos, J. Morales, Ines Antunes, Oriol Pares, Anuraag A Vazirani

Publikováno v: Seminars in Oncology. 46:246-253

Primary organ-confined prostate cancer is curable with external-beam radiotherapy. However, prostate cancer expresses a unique radiobiological phenotype, and its ablation requires doses at the high-end range of clinical radiotherapy. At this dose lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33252ed4da1e7d354724887a8ec126c9
https://doi.org/10.1053/j.seminoncol.2019.08.001

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Reproducibility and accuracy of a target motion mitigation technique for dose-escalated prostate stereotactic body radiotherapy

Autor: Maria João Cardoso, D. Mateus, Beatriz Nunes, Carlo Greco, V. Louro, Joep Stroom, Sandra Vieira, Ana R. Soares, Oriol Pares, Zvi Fuks, N. Pimentel, Justyna Kociolek

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 160

Background and purpose To quantitate the accuracy, reproducibility and prostate motion mitigation efficacy rendered by a target immobilization method used in an intermediate-risk prostate cancer dose-escalated 5×9Gy SBRT study. Material and methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f74cfe14e95cd99ec87cc1a5d86be4c
https://pubmed.ncbi.nlm.nih.gov/33992627

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Target motion mitigation promotes high-precision treatment planning and delivery of extreme hypofractionated prostate cancer radiotherapy: Results from a phase II study

Autor: V. Louro, J. Morales, Elda Freitas, N. Pimentel, Justyna Kociolek, Ana R. Soares, Maria João Cardoso, D. Mateus, Joep Stroom, Carlo Greco, Beatriz Nunes, Ana Luisa Soares Vasconcelos, Oriol Pares, Zvi Fuks, Ines Antunes, João Marques, Sandra Viera, Graca Coelho

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 146

Background and purpose While favourable long-term outcomes have been reported in organ-confined prostate cancer treated with 5 × 7–8 Gy extreme hypofractionation, dose escalation to 5 × 9–10 Gy improved local control but was associated with una

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9071a157b4af34c40d6846d63b79755b
https://pubmed.ncbi.nlm.nih.gov/32087469

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Safety and Efficacy of Virtual Prostatectomy With Single-Dose Radiotherapy in Patients With Intermediate-Risk Prostate Cancer

Autor: Ana R. Soares, V. Louro, João Marques, Graca Coelho, Zvi Fuks, Sandra Vieira, Elda Freitas, Joep Stroom, N. Pimentel, Antonio Lopez-Beltran, Oriol Pares, Manuela Seixas, Carlo Greco, D. Mateus, Inês Santiago

Publikováno v: JAMA Oncology. 7:700

Importance Ultra-high single-dose radiotherapy (SDRT) represents a potential alternative to curative extreme hypofractionated stereotactic body radiotherapy (SBRT) in organ-confined prostate cancer. Objective To compare toxic effect profiles, prostat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba17610b8e3b08d6d35728363ea97c8
https://doi.org/10.1001/jamaoncol.2021.0039

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Phenotype-Oriented Ablation of Oligometastatic Cancer with Single Dose Radiation Therapy

Autor: Oriol Pares, Durval C. Costa, Michael J. Zelefsky, Zvi Fuks, Joana C. Castanheira, Angelo Silva, J. Morales, Carlo Greco, V. Louro, Beatriz Nunes, Carla Oliveira, Richard Kolesnick, N. Pimentel, Sofia C. Vaz

Publikováno v: International journal of radiation oncology, biology, physics. 104(3)

Purpose The current oligometastatic (OM) model postulates that the disease evolves dynamically with sequential emergence of OM (SOM) lesions requiring successive rounds of SOM ablation to afford tumor cure. The present phase 2 study explores the abla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8746f5f486a69175e538420da968af1
https://pubmed.ncbi.nlm.nih.gov/30797891

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