Zobrazeno 1 - 10
of 1 184
pro vyhledávání: '"V. Lourenco"'
Autor:
Alinny R. Isaac, Mariana G. Chauvet, Ricardo Lima-Filho, Beatriz de A. Wagner, Bruno G. Caroli, Renata E. P. Leite, Claudia K. Suemoto, Paula Villela Nunes, Fernanda G. De Felice, Sergio T. Ferreira, Mychael V. Lourenco
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Major depressive disorder (MDD) is a significant cause of disability in adults worldwide. However, the underlying causes and mechanisms of MDD are not fully understood, and many patients are refractory to available therapeutic options. Impai
Externí odkaz:
https://doaj.org/article/00a284daaf5a498985eae3582d1517e8
Autor:
Felipe C. Ribeiro, Danielle Cozachenco, Luana Heimfarth, Juliana T. S. Fortuna, Guilherme B. de Freitas, Jorge M. de Sousa, Soniza V. Alves-Leon, Renata E. P. Leite, Claudia K. Suemoto, Lea T. Grinberg, Fernanda G. De Felice, Mychael V. Lourenco, Sergio T. Ferreira
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The proteasome plays key roles in synaptic plasticity and memory by regulating protein turnover, quality control, and elimination of oxidized/misfolded proteins. Here, we investigate proteasome function and localization at synapses in Alzhei
Externí odkaz:
https://doaj.org/article/bdf4804051b140dd9c552fb96120595a
Autor:
Marco Antônio De Bastiani, Bruna Bellaver, Giovanna Carello-Collar, Maria Zimmermann, Peter Kunach, Ricardo A.S. Lima-Filho, Stefania Forner, Alessandra Cadete Martini, Tharick A. Pascoal, Mychael V. Lourenco, Pedro Rosa-Neto, Eduardo R. Zimmer
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108671- (2024)
Summary: Alzheimer’s disease (AD) is a multifactorial pathology, with most cases having a sporadic origin. Recently, knock-in (KI) mouse models, such as the novel humanized amyloid-β (hAβ)-KI, have been developed to better resemble sporadic human
Externí odkaz:
https://doaj.org/article/e4b444db5ed14a0b8880174f4ad5e107
Autor:
Fabricio A. Pamplona, Gabriela Vitória, Felipe K. Sudo, Felipe C. Ribeiro, Alinny R. Isaac, Carolina A. Moraes, Mariana G. Chauvet, Pitia Flores Ledur, Karina Karmirian, Isis M. Ornelas, Luciana M. Leo, Bruna Paulsen, Gabriel Coutinho, Claudia Drummond, Naima Assunção, Bart Vanderborght, Claudio A. Canetti, Hugo C. Castro-Faria-Neto, Paulo Mattos, Sergio T. Ferreira, Stevens K. Rehen, Fernando A. Bozza, Mychael V. Lourenco, Fernanda Tovar-Moll
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Age increases the risk for cognitive impairment and is the single major risk factor for Alzheimer’s disease (AD), the most prevalent form of dementia in the elderly. The pathophysiological processes triggered by aging that render the brain
Externí odkaz:
https://doaj.org/article/223c09f5661f4ecea1670a848dcc0279
Autor:
Mychael V. Lourenco, Wyllians Vendramini Borelli, Claudia Duran‐Aniotz, Eduardo R. Zimmer, Shamyr Sulyvan deCastro
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 1, Pp n/a-n/a (2023)
Abstract Alzheimer's disease (AD) is a global health issue. Because AD is a condition demanding effective management, its socioeconomic burden is immense and threatens the health systems of both low‐ and middle‐income (LMIC) and high‐income (HI
Externí odkaz:
https://doaj.org/article/c2496b4bd7e14435a6c5fe8b7c2e2bc0
Akademický článek
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Autor:
Mychael V. Lourenco, Guilherme B. de Freitas, Ícaro Raony, Sergio T. Ferreira, Fernanda G. De Felice
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Physical exercise stimulates neuroprotective pathways, has pro-cognitive actions, and alleviates memory impairment in Alzheimer’s disease (AD). Irisin is an exercise-linked hormone produced by cleavage of fibronectin type III domain containing prot
Externí odkaz:
https://doaj.org/article/5dbc1562f2734bb48a28bef392bfba9c
Autor:
Jose A. Plaza, Alejandro A. Gru, Omar P. Sangueza, Silvia V. Lourenco, Francisco B. Puccio, Jose A. Sanches, Denis Miyashiro, Sonia Toussaint, Martin J. Sangueza
Publikováno v:
Journal of the American Academy of Dermatology. 88:965-980
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a968cbba1dfc38ca49f26bfd9518b0
https://doi.org/10.1016/j.jaad.2021.11.068
https://doi.org/10.1016/j.jaad.2021.11.068
Autor:
Mychael V. Lourenco, Felipe C. Ribeiro, Felipe K. Sudo, Cláudia Drummond, Naima Assunção, Bart Vanderborght, Fernanda Tovar‐Moll, Paulo Mattos, Fernanda G. De Felice, Sergio T. Ferreira
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction: Irisin is a novel hormone originally identified for its role as a regulator of peripheral metabolism and recently found to protect synapses and rescue memory in mouse models of Alzheimer's disease (AD). However, whether and how
Externí odkaz:
https://doaj.org/article/8a5ca10eef21424eaf6f8964c32a4e85
Akademický článek
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