Zobrazeno 1 - 10
of 21
pro vyhledávání: '"V. Lauriault"'
Autor:
Nasrin R. Mawji, Han-Jie Zhou, Raymond J. Andersen, Peter Virsik, P. Pearson, Nan Hyung Hong, Carmen Adriana Banuelos, Marianne D. Sadar, V. Lauriault, Teresa Tam, Jinhai Wang, R. Le Moigne, Alessandra Cesano
Publikováno v:
European Journal of Cancer. 138:S51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a89527e858a78f7777aa194d36718443
https://doi.org/10.1016/s0959-8049(20)31212-0
https://doi.org/10.1016/s0959-8049(20)31212-0
Autor:
P. Pearson, Carmen Adriana Banuelos, Nan Hyung Hong, Jinhai Wang, Alessandra Cesano, Peter Virsik, Teresa Tam, R. Le Moigne, Marianne D. Sadar, Raymond J. Andersen, Nasrin R. Mawji, H-J. Zhou, V. Lauriault
Publikováno v:
Annals of Oncology. 31:S475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13504d1efba91d4c4abcfe55922c3946
https://doi.org/10.1016/j.annonc.2020.08.659
https://doi.org/10.1016/j.annonc.2020.08.659
Autor:
Shannon L. Winski, A. Drilon, Karyn Bouhana, Vamsidhar Velcheti, Dahlia Henry, Mark E. Burkard, Naifa L. Busaidy, Stephen M. Rothenberg, Maria E. Cabanillas, D. Hartley, R. Hamor, Barbara J. Brandhuber, Steve Andrews, R. D. Wallace, S. Rhodes, S. Stock, V. Lauriault, Vivek Subbiah, S. Corsi-Travali, Lori J. Wirth, Brian B. Tuch, M.G. Muni Reddy, Steven J. Smith, Kevin Ebata
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 29(8)
Background Alterations involving the RET kinase are implicated in the pathogenesis of lung, thyroid and other cancers. However, the clinical activity of multikinase inhibitors (MKIs) with anti-RET activity in RET-altered patients appears limited, cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f036f69cc0069ad242760eeaf45c4c35
https://pubmed.ncbi.nlm.nih.gov/29860429
https://pubmed.ncbi.nlm.nih.gov/29860429
Publikováno v:
Chemico-Biological Interactions. 81:271-289
The objective of this study was to determine whether the thiol drug, diethyldithiocarbamate (DEDC) and its two metabolites, disulfiram (DS) and carbon disulfide (CS2) could be used as inhibitors of cytochrome P-450IIE1 to protect hepatocytes from cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26377d4a17abee3cc0d482987af89265
https://doi.org/10.1016/0009-2797(92)90082-v
https://doi.org/10.1016/0009-2797(92)90082-v
Publikováno v:
Xenobiotica. 20:933-943
1. Bromotrichloromethane added to isolated rat hepatocytes resulted in increased cell death as determined by trypan blue uptake. Toxicity increased in a concentration-dependent fashion between 2.0-5.0 M bromotrichloromethane. 2. Lipid peroxidation (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd31b855a04d2f301ce6cb2bb9350631
https://doi.org/10.3109/00498259009046909
https://doi.org/10.3109/00498259009046909
Autor:
V V, Lauriault, P J, O'Brien
Publikováno v:
Molecular pharmacology. 40(1)
The present study was carried out to elucidate the mechanism by which the permeable thiol drug diethyldithiocarbamate (DEDC) exhibited an antidotal effect against acetaminophen-induced hepatotoxicity in vivo. DEDC was found to act as an antidote agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a9ad7bdd98a615aeb7c01d1df239276
https://pubmed.ncbi.nlm.nih.gov/1649964
https://pubmed.ncbi.nlm.nih.gov/1649964
Publikováno v:
Archives of biochemistry and biophysics. 284(1)
The increase in 1,4-naphthoquinone-2-sulfonate (NQS)-induced hemolysis by the superoxide dismutase inhibitor diethyldithiocarbamate (DEDC) was formerly attributed to increased superoxide anion levels in the erythrocyte. Our results show that removal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d644c821870105a2485160aad9193
https://pubmed.ncbi.nlm.nih.gov/1846514
https://pubmed.ncbi.nlm.nih.gov/1846514
Publikováno v:
Archives of biochemistry and biophysics. 282(1)
The copper-chelating thiol drug diethyldithiocarbamate protected isolated hepatocytes from benzoquinone-induced alkylation cytotoxicity by reacting with benzoquinone and forming a conjugate which was identified by fast atom bombardment mass spectrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73de859d409f695362292f25536af665
https://pubmed.ncbi.nlm.nih.gov/2171431
https://pubmed.ncbi.nlm.nih.gov/2171431
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Akademický článek
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