Zobrazeno 1 - 10
of 34
pro vyhledávání: '"V. L. Raghavendra Rao"'
Publikováno v:
Journal of Neurochemistry. 66:701-709
The kinetics and pharmacology of N G -nitro-L-[2,3,4,5- 3 H]arginine (L-[ 3 H]NOARG) binding to rat cerebellum were investigated using in vitro radioligand binding. Specific L-[ 3 H]NOARG binding in cerebellum was of nanomolar affinity, reversible, s
Publikováno v:
Acta Neurochirurgica. 141:1107-1113
Memantine, an uncompetitive NMDA open-channel blocker, has been shown to be effective in preventing neuronal damage after permanent focal cerebral ischemia. Reperfusion after a long period of ischemia may aggravate the progression of neuronal damage.
Autor:
Mustafa K. Baskaya, Aclan Dogan, James F. Hatcher, Robert J. Dempsey, V. L. Raghavendra Rao, A. Muralikrishna Rao
Publikováno v:
Journal of Neurochemistry. 72:765-770
The possible effects of the polyamine interconversion pathway on tissue polyamine levels, brain edema formation, and ischemic injury volume were studied by using a selective irreversible inhibitor, MDL 72527, of the interconversion pathway enzyme, po
Publikováno v:
European Journal of Pharmacology. 340:89-99
The kinetics and pharmacology of the isoquinoline and benzodiazepine binding sites of the ω3 or peripheral-type benzodiazepine receptors were studied using the specific ligands [3H] 7-chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazep
Autor:
A. Muralikrishna Rao, Aclan Doğgan, Mustafa K. Baskaya, V. L. Raghavendra Rao, Jane Rastl, Robert J. Dempsey, David Donaldson
Publikováno v:
Journal of Neurosurgery. 87:921-926
✓ Polyamines and N-methyl-d-aspartate (NMDA) receptors are both thought to play an important role in secondary neuronal injury after cerebral ischemia. Ifenprodil, known as a noncompetitive inhibitor of polyamine sites at the NMDA receptor, was stu
Publikováno v:
Brain Research. 765:169-172
It has previously been suggested that increases of l-arginine uptake into brain following portacaval shunting may result in increased activities of constitutive neuronal nitric oxide synthase (nNOS). In order to further address this issue, nNOS prote
Publikováno v:
Neuroscience Letters. 208:17-20
Pyrithiamine-induced thiamine deficiency in the rat exhibits many neuropathological and biochemical similarities to Wernicke's Encephalopathy in human. Activities of constitutive nitric oxide synthase (NOS) were measured in vulnerable (thalamus and c
Autor:
Roger F. Butterworth, Maryse Héroux, J. Stephen Richardson, V. L. Raghavendra Rao, Joël Lavoie
Publikováno v:
Metabolic Brain Disease. 11:81-88
There is a growing body of evidence to suggest that thiamine neurochemistry is disrupted in Alzheimer's Disease (AD). Studies in autopsied brain tissue from neuropathologically proven AD patients reveal significantly reduced activities of the thiamin
Publikováno v:
Neuroscience Letters. 182:69-72
Affinities and densities of binding sites for the 5HT1A receptor ligand [3H]8-hydroxy(di-n-propylamino)tetralin ([3H]8-OH-DPAT) and the 5HT2 receptor ligand [3H]ketanserin were measured using a rapid filtration assay in crude membrane preparations fr
Publikováno v:
Neuroscience Letters. 170:27-30
Activities of monoamine oxidases, MAOA and MAOB, were measured using radiometric assays in different brain regions of the sparse-fur (spf/Y) mouse, a model of congenital hyperammonemia resulting from an X-chromosomal defect of ornithine transcarbamyl