Výsledky vyhledávání

Induction of increased levels of proteoglycan fragments in synovial fluid (SF) and increased levels of stromelysin in cartilage, synovium and SF by intraarticular injection of canine monocyte conditioned medium into dogs

Autor: M W, Lark, K A, MacNaul, S, Donatelli, J, McDonnell, L A, Hoerrner, K A, Stevens, C A, Saphos, E K, Bayne, N I, Hutchinson, V L, Moore

Publikováno v: The Journal of rheumatology. 21(9)

To study the effects of the intraarticular injection of canine monocyte conditioned medium (cMCM) into dogs on proteoglycan fragment and stromelysin levels in the joint.cMCM was injected intraarticularly into dogs, and the levels of proteoglycan frag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e71a1d6afb9804496e6996c1c40c6edf
https://pubmed.ncbi.nlm.nih.gov/7799356

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In vivo activity of human recombinant tissue inhibitor of metalloproteinases (TIMP). Activity against human stromelysin in vitro and in the rat pleural cavity

Autor: M W, Lark, C A, Saphos, L A, Walakovits, V L, Moore

Publikováno v: Biochemical pharmacology. 39(12)

Recombinant human tissue inhibitor of metalloproteinase (rhTIMP) suppressed the ability of native human stromelysin to degrade [3H]transferrin in vitro. Maximum inhibition occurred at molar ratios (TIMP: stromelysin) of 2:1 and 1:1. Reduced and alkyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4398a1878d8d0d7cc3400a77a36923ec
https://pubmed.ncbi.nlm.nih.gov/2353943

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Immunogenetics of BCG-induced anergy in mice: control by genes linked to the Igh complex

Autor: D J Schrier, J L Sternick, E M Allen, V L Moore

Publikováno v: The Journal of Immunology. 128:1466-1469

The genetics of BCG-induced anergy was studied in mice by evaluating delayed hypersensitivity to sheep erythrocytes. Data obtained using congenic mice and by linkage analysis suggested that genes linked to the H-2 complex do not influence the develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e1b5ddf3542fee08c8614b7c0c18c12
https://doi.org/10.4049/jimmunol.128.3.1466

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Strain variation in BCG-induced chronic pulmonary inflammation in mice: control by a cyclophosphamide-sensitive thymus-derived suppressor cell

Autor: V L Moore, V M Mondloch, G M Pedersen, D J Schrier, E M Allen

Publikováno v: The Journal of Immunology. 127:339-342

We previously reported that only certain strains of inbred mice develop intense chronic granulomatous inflammation (CGI) in the lungs and spleen in response to an i.v. injection of killed BCG in an oil-in-saline emulsion (BCG-E). The capacity to resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::beca6ef15cc5f4941f9433811cb4a919
https://doi.org/10.4049/jimmunol.127.1.339

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Experimental murine hypersensitivity pneumonitis: multigenic control and influence by genes within the I-B subregion of the H-2 complex

Autor: B D, Wilson, J L, Sternick, Y, Yoshizawa, A L, Katzenstein, V L, Moore

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 129(5)

An animal model of hypersensitivity pneumonitis was developed in the mouse by immunization with pigeon dropping extract (PDE) in complete Freund's adjuvant, followed by daily aerosol challenge with soluble specific antigen. C3H/He (H-2k) mice develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d7d35de46c99fee17ace23a53342951
https://pubmed.ncbi.nlm.nih.gov/6811659

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