Zobrazeno 1 - 10
of 248
pro vyhledávání: '"V. Keith"'
Autor:
Xiuxiu Lu, Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie, Bradley T. Scroggins, Sudipto Das, Wazo Myint, Michelle E. Clapp, Charles D. Schwieters, Marzena A. Dyba, Derek L. Bolhuis, Janusz W. Koscielniak, Thorkell Andresson, Michael J. Emanuele, Nicholas G. Brown, Hiroshi Matsuo, Raj Chari, Deborah E. Citrin, Beverly A. Mock, Rolf E. Swenson, Kylie J. Walters
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Proteasome subunit hRpn13 is partially proteolyzed in certain cancer cell types to generate hRpn13Pru by degradation of its UCHL5/Uch37-binding DEUBAD domain and retention of an intact proteasome- and ubiquitin-binding Pru domain. By using s
Externí odkaz:
https://doaj.org/article/287afc8f95ca4e0dbcecccb50eebdb48
Autor:
Anju Kumari, Lisa Gesumaria, Yan-Jin Liu, V. Keith Hughitt, Xiaohu Zhang, Michele Ceribelli, Kelli M. Wilson, Carleen Klumpp-Thomas, Lu Chen, Crystal McKnight, Zina Itkin, Craig J. Thomas, Beverly A. Mock, David S. Schrump, Haobin Chen
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Small cell lung cancer (SCLC) is a recalcitrant malignancy with limited treatment options. Bromodomain and extraterminal domain inhibitors (BETis) have shown promising preclinical activity in SCLC, but the broad sensitivity spectrum limits their clin
Externí odkaz:
https://doaj.org/article/486952269d6442e6887641df9fd39b64
Autor:
Jeff Quigley, V. Keith Hughitt, Carlos A. Velikovsky, Roy A. Mariuzza, Najib M. El-Sayed, Volker Briken
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wa
Externí odkaz:
https://doaj.org/article/0e3bad085cc34cf9b1eece179b714cd2
Autor:
Ehud Inbar, V. Keith Hughitt, Laura A. L. Dillon, Kashinath Ghosh, Najib M. El-Sayed, David L. Sacks
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT The life cycle of the Leishmania parasite in the sand fly vector involves differentiation into several distinctive forms, each thought to represent an adaptation to specific microenvironments in the midgut of the fly. Based on transcriptome
Externí odkaz:
https://doaj.org/article/0237bcd8c10b4444ae0c597be089eebf
Autor:
Peat, Tyler J., Gaikwad, Snehal M., Dubois, Wendy, Gyabaah-Kessie, Nana, Zhang, Shuling, Gorjifard, Sayeh, Phyo, Zaw, Andres, Megan, Hughitt, V. Keith, Simpson, R. Mark, Miller, Margaret A., Girvin, Andrew T., Taylor, Andrew, Williams, Daniel, D'Antonio, Nelson, Zhang, Yong, Rajagopalan, Adhithi, Flietner, Evan, Wilson, Kelli, Zhang, Xiaohu, Shinn, Paul, Klumpp-Thomas, Carleen, McKnight, Crystal, Itkin, Zina, Chen, Lu, Kazandijian, Dickran, Zhang, Jing, Michalowski, Aleksandra M., Simmons, John K., Keats, Jonathan, Thomas, Craig J., Mock, Beverly A.
Publikováno v:
In Cancer Letters 1 August 2023 568
Autor:
Ireland, Jack, Inglis, Andrew R., Shih, Albert Y., Christe, Steven, Mumford, Stuart J., Hayes, Laura A., Thompson, Barbara J., Hughitt, V. Keith
Publikováno v:
Solar Physics (2019), 294, 158
Extreme ultraviolet (EUV) waves are large-scale propagating disturbances observed in the solar corona, frequently associated with coronal mass ejections and flares. They appear as faint, extended structures propagating from a source region across the
Externí odkaz:
http://arxiv.org/abs/1804.07325
Akademický článek
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A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins.
Autor:
Lu, Xiuxiu, Chandravanshi, Monika, Sabbasani, Venkata R., Gaikwad, Snehal, Hughitt, V. Keith, Gyabaah-Kessie, Nana, Scroggins, Bradley T., Das, Sudipto, Myint, Wazo, Clapp, Michelle E., Schwieters, Charles D., Dyba, Marzena A., Bolhuis, Derek L., Koscielniak, Janusz W., Andresson, Thorkell, Emanuele, Michael J., Brown, Nicholas G., Matsuo, Hiroshi, Chari, Raj, Citrin, Deborah E.
Publikováno v:
Nature Communications; 3/20/2024, Vol. 15 Issue 1, p1-18, 18p
Akademický článek
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Publikováno v:
Plant Disease. 107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3733592741d64b796740242ad7751c61
https://doi.org/10.1094/pdis-06-22-1449-pdn
https://doi.org/10.1094/pdis-06-22-1449-pdn