Zobrazeno 1 - 10
of 68
pro vyhledávání: '"V. K. Potapov"'
Publikováno v:
Molecular Genetics, Microbiology and Virology. 34:220-227
One of the most popular nonviral delivery systems for gene therapy constructs are carriers based on polyethylenimine (PEI) DNA complexes. A number of disadvantages associated with the lack of targeted delivery and increased cytotoxicity are overcome
Autor:
A. V. Sass, A. V. Vvedensky, Lev G. Nikolaev, Eugene D. Sverdlov, M. V. Zinovyeva, V. K. Potapov
Publikováno v:
Molecular Genetics, Microbiology and Virology. 33:187-194
Naturally occurring positively charged proteins can be promising carriers for nucleic acid transport in gene therapy. The most attractive alternative among them is histones. In this work, we describe expression and purification of recombinant human h
Publikováno v:
Molecular Genetics, Microbiology and Virology. 33:15-20
To improve the safety profile and specificity in cancer gene therapy applications, а set of singleplasmid vectors for expression of suicide thymidine kinase gene of the herpes simplex virus (HSVtk) and mouse OX40L gene (m0X40L) involved in regulatio
Autor:
Raisa I. Yakubovskaya, O. B. Filyukova, O. A. Bezborodova, I. V. Alekseenko, V. K. Potapov, Eugene D. Sverdlov, A. A. Pankratov, E. R. Nemtsova, M. B. Kostina
Publikováno v:
Doklady Biochemistry and Biophysics. 483:326-328
In this study, we evaluated the antitumor activity of a gene therapy complex in which the tumor-specific control of the expression of the effector suicide gene FCU1 was performed using a two-vector system based on the site-specific Cre-LoxP recombina
Autor:
Olga Rakitina, A. I. Kuzmich, V. K. Potapov, I. V. Alekseenko, M. V. Zinovyeva, Eugene D. Sverdlov, D. A. Didych
Publikováno v:
Polymers, Vol 12, Iss 1695, p 1695 (2020)
Polymers
Volume 12
Issue 8
Polymers
Volume 12
Issue 8
Nuclear proteins, like histone H2A, are promising non-viral carriers for gene delivery since they are biocompatible, biodegradable, bear intrinsic nuclear localization signal, and are easy to modify. The addition of surface-protein-binding ligand to
Autor:
V. K. Potapov, N. V. Amirkhanov, Lev G. Nikolaev, V. S. Mikhailov, R. N. Amirkhanov, Valentina F. Zarytova, S. S. Bulanenkova, S. B. Akopov, Eugene D. Sverdlov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 39:72-76
The ability of short peptide nucleic acid (PNA) oligomers and oligonucleotides containing modified residues of 5-methylcitidine, 2-aminoadenosine, and 5-propynyl-2′-deoxyuridine (strong binding oligonucleotides, SBO) to affinity capture the target
Publikováno v:
Molecular Genetics Microbiology and Virology (Russian version). 36:3
Publikováno v:
Molecular Genetics Microbiology and Virology (Russian version). 36:30
Publikováno v:
Molecular Genetics Microbiology and Virology (Russian version). 36:14
Publikováno v:
Russian Journal of Physical Chemistry A. 82:1415-1418
The mechanism and kinetics of hydrogen adsorption on Pd/Ni nanostructures on an Al2O3 surface were studied. The dependence of electrical conductivity on the degree of hydrogen adsorption and the temperature effect on the rate of adsorption were deter