Zobrazeno 1 - 10
of 62
pro vyhledávání: '"V. K. Kibirev"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 5, Pp 28-33 (2018)
Furin belongs to a family of calcium-dependent serine proprotein convertases, which transform the inactive protein precursors into mature polypeptides. In model experiments, we studied the effect of organic solvents such as acetone, dimethyl sulfoxid
Externí odkaz:
https://doaj.org/article/5a41a16bb75c484f8b5d1d2195dafd3a
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 6, Pp 3-12 (2017)
The proprotein convertase furin plays a crucial role in a variety of pathogenic processes such as cancer, bacterial and viral diseases, neurodegenerative disorders and diabetes. Thus, furin inhibitors are promising therapeutics for the treatment of
Externí odkaz:
https://doaj.org/article/b4730ca19f0949daae19f92751b940bd
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 15-20 (2017)
Furin is the most studied proprotein convertase which processes inactive protein precursors, converting them into biologically active polypeptides. We have investigated cation effects of cesium, strontium, cadmium, iron, cobalt and nickel on the furi
Externí odkaz:
https://doaj.org/article/2156249f7ba44af09da595aa0d94ed79
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 6, Pp 5-25 (2016)
The review is devoted to the analysis of the relationship between a chemical structure and properties of low-molecular weight inhibitors of furin, the most studied proprotein convertase, which is involved in the development of some pathologies, such
Externí odkaz:
https://doaj.org/article/19f14df485474369acbe602840c4304c
Autor:
V. K. Kibirev, T. V. Osadchuk, O. P. Kozachenko, V. Kholodovych, O. D. Fedoryak, V. S. Brovarets
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 1, Pp 55-63 (2015)
A series of novel non-peptidic furin inhibitors with values of inhibitory constants (Ki) in the range of 0.74-1.54 μM was obtained by interactions of aminoguanidine hydrocarbonate with three diaryldicarbaldehydes. Correspondingly p-hydroquinone, pip
Externí odkaz:
https://doaj.org/article/3fb683d48cae4fb3b3c82b31e695f23e
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 1, Pp 22-32 (2013)
A series of novel non-peptidic furin inhibitors containing amidinohydrazone moieties has been synthesized under interaction of dialdehydes, the derivatives of ethylene diethylvanillin ethers, with aminoguanidine bicarbonate. Two aryl cycles were brid
Externí odkaz:
https://doaj.org/article/8507eba8fb734d6f92271690c9a407d9
Publikováno v:
Ukrainian Biochemical Journal, Vol 90, Iss 5, Pp 28-33 (2018)
Furin belongs to a family of calcium-dependent serine proprotein convertases, which transform the inactive protein precursors into mature polypeptides. In model experiments, we studied the effect of organic solvents such as acetone, dimethyl sulfoxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eff32e318701252bfce95a3d3ed0d36
http://ukrbiochemjournal.org/2018/09/influence-of-organic-solvents-on-the-furin-activity.html
http://ukrbiochemjournal.org/2018/09/influence-of-organic-solvents-on-the-furin-activity.html
Publikováno v:
Ukrainian Biochemical Journal, Vol 88, Iss 6, Pp 5-25 (2016)
The review is devoted to the analysis of the relationship between a chemical structure and properties of low-molecular weight inhibitors of furin, the most studied proprotein convertase, which is involved in the development of some pathologies, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a481cb17f2448073a181e9797f789a
https://doi.org/10.15407/ubj88.06.005
https://doi.org/10.15407/ubj88.06.005
Publikováno v:
Ukrainian biochemical journal. 87(3)
The aim of this work was to study antifurin activity of some derivatives of calix[4]arenes modified on the upper rim of the macrocycle by positively charged or uncharged groups. It was found that calixarene CX3im derivatives containing positively cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb6913c4b6649de725eb838931eed065
https://pubmed.ncbi.nlm.nih.gov/26502697
https://pubmed.ncbi.nlm.nih.gov/26502697
Publikováno v:
Russian Journal of Bioorganic Chemistry. 29:220-226
Boc/Tos-L-Phe-L-Arg-Xaa tripeptides (where Xaa = L-Ala-OBut, L-Ala, or DL-AlaP (OC2H5)2) were synthesized by conventional methods of peptide synthesis in solution. Special features of their interaction with thrombin and trypsin were studied. Unlike t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba91ccb63500c56b39bdeff802664ef1
https://doi.org/10.1023/a:1023976230702
https://doi.org/10.1023/a:1023976230702