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2-Aminopurine Overrides a Late Telophase Delay Created by Ectopic Expression of the PITSLREβ1 Protein Kinase

Autor: V. J. Kidd, J. M. Lahti, Jialing Xiang

Publikováno v: Biochemical and Biophysical Research Communications. 199:1167-1173

Minimal overexpression of the PITSLRE beta 1 protein kinase in CHO cells leads to a marked delay in late mitosis. We have previously shown that this delay is characterized by the presence of substantially increased numbers of tubulin midbodies, inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6135af3a006f35db55509d95c351c2
https://doi.org/10.1006/bbrc.1994.1353

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Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism

Autor: H S, Chun, G E, Gibson, L A, DeGiorgio, H, Zhang, V J, Kidd, J H, Son

Publikováno v: Journal of neurochemistry. 76(4)

Recent etiological study in twins (Tanner et al. 1999) strongly suggests that environmental factors play an important role in typical, non-familial Parkinson's disease (PD), beginning after age 50. Epidemiological risk factor analyses of typical PD c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3665c4e0fdbf1c16e4f495082ab188b
https://pubmed.ncbi.nlm.nih.gov/11181820

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Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases

Autor: M E, Ariza, M, Broome-Powell, J M, Lahti, V J, Kidd, M A, Nelson

Publikováno v: The Journal of biological chemistry. 274(40)

The Cdc2L locus encoding the PITSLRE protein kinases maps to chromosome band 1p36 and consists of two duplicated and tandemly linked genes. The purpose of the present study was to determine whether diminution of PITSLRE kinases leads to deregulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::61612a858476ced666ee9e702e1e1466
https://pubmed.ncbi.nlm.nih.gov/10497214

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Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma

Autor: J, Easton, T, Wei, J M, Lahti, V J, Kidd

Publikováno v: Cancer research. 58(12)

The p16INK4a (MTS1) and pl8INK4c gene products are normal, and highly expressed, in human neuroblastoma cell lines. The retinoblastoma protein (pRb) was, nonetheless, phosphorylated and functional in these cells. Such high levels of p16INK4a/p18INK4c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ee39806c6fbe2a775d48ae9c953a86b1
https://pubmed.ncbi.nlm.nih.gov/9635589

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Mapping of five members of the cyclin gene family on chicken chromosomes by FISH

Autor: J, Masabanda, R, Friedl, A, Sazanov, J M, Lahti, H, Li, V J, Kidd, R, Fries

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 6(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7007def6cf0979d4d0aa32f8c58f41e8
https://pubmed.ncbi.nlm.nih.gov/9609667

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Alternatively spliced cyclin C mRNA is widely expressed, cell cycle regulated, and encodes a truncated cyclin box

Autor: H, Li, J M, Lahti, V J, Kidd

Publikováno v: Oncogene. 13(4)

The cyclin C protein has recently been shown to associate with a unique cyclin dependent protein kinase (cdk8) and it has been proposed that this complex may regulate RNA transcription during the cell cycle. In addition, the human cyclin C gene has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03a014aa06aca53fe5ab5b942fee6683
https://pubmed.ncbi.nlm.nih.gov/8761291

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The PITSLRE protein kinase family

Autor: J M, Lahti, J, Xiang, V J, Kidd

Publikováno v: Progress in cell cycle research. 1

A family of p34Cdc2 related protein kinases, the PITSLRE kinases, is generated by alternative splicing and promoter utilization from three duplicated and tandemly linked genes on human chromosome 1p36.3, which is frequently deleted during the late st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::327cad87c6448e791bbcbc935ce558bd
https://pubmed.ncbi.nlm.nih.gov/9552375

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Properties of IgA-binding receptors on murine T cells: relative importance of Fc alpha R, beta-galactosyltransferase and anti-secretory component reactive proteins (ASCP)

Autor: John H. Eldridge, M. L. McGHEE, Zina Moldoveanu, V. J. Kidd, W. K. Aicher, Jiri Mestecky, Milan Tomana, Hiroshi Kiyono, Jerry R. McGhee, Thomas F. Meyer

Publikováno v: Scandinavian journal of immunology. 35(4)

Murine T cells and T-cell lines express receptors for the Fc of IgA (FcαR); however, their molecular properties remain to be elucidated. In the present study, we examined three candidate molecules for IgA-binding receptors including FcαR, β-galact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b08bbd38f428f5294cc7505df749e4
https://pubmed.ncbi.nlm.nih.gov/1557614

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Regulation of the p58GTA cell division control-related protein kinase during phorbol 12-myristate 13-acetate-induced terminal differentiation of U937 cells

Autor: A S, Kraft, S S, Wang, J, Xiang, L, Pouncey, V J, Kidd

Publikováno v: Oncogene. 7(3)

We describe the regulation of expression, activity and subcellular localization of a cell cycle control-related kinase, p58GTA, during the withdrawal from the cell cycle of U937 human leukemic cells induced by phorbol esters. Our studies indicate tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91581f697e1844432014bd741d8411eb
https://pubmed.ncbi.nlm.nih.gov/1549364

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