Zobrazeno 1 - 10
of 44
pro vyhledávání: '"V. J. A. Schouten"'
Publikováno v:
Journal of Molecular and Cellular Cardiology. 23:1039-1050
The inward Ca2+ current, ica, increases with the frequency of stimulation in single ventricular myocytes, but the presence and possible role of this phenomenon in intact heart muscle of mammals has not been studied. The present study addresses the qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d169d46435cff1877e6323148f8dec60
https://doi.org/10.1016/0022-2828(91)91639-9
https://doi.org/10.1016/0022-2828(91)91639-9
Publikováno v:
Basic Research in Cardiology. 85:563-574
Contractility is often depressed in isolated heart muscle. To analyze this phenomenon, we measured the derivative of left ventricular pressure (dP/dt) in intact and in isolated, blood perfused pig hearts, and peak force (F) or stress (F/mm2) in ventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb5b6bb53af90740f0a211270365b9b
https://doi.org/10.1007/bf01907891
https://doi.org/10.1007/bf01907891
Publikováno v:
Cardiovascular Research. 24:758-767
Study objective – The plateau of the action potential in heart muscle is largely due to the inward Ca2+ current, ica; however, Ca2+ extrusion via Na+/Ca2+ exchange may also generate a significant current, ina/ca. The aim was to assess the influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05129e498f5ffff7bd9d13d499927b6f
https://doi.org/10.1093/cvr/24.9.758
https://doi.org/10.1093/cvr/24.9.758
Publikováno v:
The Journal of physiology. 451
1. Increased coronary perfusion leads to increased myocardial contraction and oxygen consumption (Gregg's phenomenon) even when oxygen supply is presumably sufficient. Previous studies concerned whole hearts, however, in which local hypoxia may play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2594c7b86d00e35db2dc307647200a
https://pubmed.ncbi.nlm.nih.gov/1403826
https://pubmed.ncbi.nlm.nih.gov/1403826
Publikováno v:
The American journal of physiology. 260(1 Pt 2)
Depressed function of postischemic hearts may be related to incomplete recovery of coronary perfusion. To circumvent this factor we studied the properties of papillary muscles under controlled extracellular conditions. First, recovery of function was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9270c31cabd12e495fd1d69b6945275
https://pubmed.ncbi.nlm.nih.gov/1992811
https://pubmed.ncbi.nlm.nih.gov/1992811
Autor:
V. J. A. Schouten
Publikováno v:
The Journal of physiology. 431
1. The influence of the interstimulus interval on twitch duration was analysed in isolated heart muscle of the rat. When the muscle was in the steady state at interstimulus intervals at 5 s a test interval was interposed and varied. Duration of twitc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e7a33bbb528ca32912716543c8f9b
https://pubmed.ncbi.nlm.nih.gov/2100313
https://pubmed.ncbi.nlm.nih.gov/2100313
Publikováno v:
Circulation research. 67(4)
Inotropic interventions were compared with respect to their maximum effect on force of contraction in rat myocardium to identify limiting steps in calcium handling. Peak force, sarcomere length, and action potentials were measured in thin ventricular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609cbefffe2625d157a13221ba4ea869
https://pubmed.ncbi.nlm.nih.gov/2208614
https://pubmed.ncbi.nlm.nih.gov/2208614
Publikováno v:
Journal of molecular and cellular cardiology. 22(9)
Left or right ventricular hypertrophy was induced by banding of the aorta or pulmonary artery in different groups of rats. After 5 to 10 weeks the degree of hypertrophy was about 15% in left and 80–1605 in right ventricles, as determined by weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8912f62a0926c11a558bd201afd411f9
https://pubmed.ncbi.nlm.nih.gov/2149151
https://pubmed.ncbi.nlm.nih.gov/2149151
Autor:
H E ter Keurs, V. J. A. Schouten
Publikováno v:
The Journal of Physiology. 360:13-25
Intracellular action potentials and isometric force were measured from thin trabeculae of the right ventricle of rat heart. Characteristic for the action potential of rat myocardium is a short plateau and a slow final repolarization phase. We have st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073b6c231e4015c091e8db6e04723581
https://doi.org/10.1113/jphysiol.1985.sp015601
https://doi.org/10.1113/jphysiol.1985.sp015601
Autor:
V. J. A. Schouten
Publikováno v:
Journal of Molecular and Cellular Cardiology. 18:1033-1045
Action potential duration at 50% of the amplitude (APD 50 ) and peak force of isometric contractions were recorded from right ventricular trabeculae of rat heart at 26°C. When the preparation was in the steady state at 0.2 Hz, a varied test interval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d272437bcaf3cea98774e713b1ddc47b
https://doi.org/10.1016/s0022-2828(86)80291-7
https://doi.org/10.1016/s0022-2828(86)80291-7