Blood Leukocyte Levels Are Associated with Radiological Progression of Early Fibrotic ILA Within Five Years

Autor: A. Achaiah, P. Lyon, E. Fraser, P. Saunders, R. Benamore, V. Iotchkova, R. Hoyles, L.-P. Ho

Publikováno v: D92. TRYING TO NIP IT IN THE BUD: ADVANCES IN UNDERSTANDING INTERSTITIAL LUNG ABNORMALITIES.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ceced3b84cc3215cec7094d31b33f22
https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5272

Neutrophil lymphocyte ratio as an indicator for disease progression in Idiopathic Pulmonary Fibrosis.

Autor: Achaiah A; MRC Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK.; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Rathnapala A; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Pereira A; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Bothwell H; Undergraduate Education, Great Western Hospitals NHS Foundation Trust, Swindon, UK., Dwivedi K; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Barker R; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Iotchkova V; MRC Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK., Benamore R; Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Hoyles RK; Centre for Respiratory Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Ho LP; MRC Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, UK ling-pei.ho@imm.ox.ac.uk.; Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford, UK.

Publikováno v: BMJ open respiratory research [BMJ Open Respir Res] 2022 Jun; Vol. 9 (1).

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.

Autor: Min JL; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. josine.min@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. josine.min@bristol.ac.uk., Hemani G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Hannon E; University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UK., Dekkers KF; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Castillo-Fernandez J; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Luijk R; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Carnero-Montoro E; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Pfizer-University of Granada-Andalusian Government Center for Genomics and Oncological Research, Granada, Spain., Lawson DJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Burrows K; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Suderman M; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bretherick AD; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Richardson TG; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Klughammer J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Iotchkova V; MRC Weatherall Institute of Molecular Medicine, Oxford, UK., Sharp G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Al Khleifat A; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK., Shatunov A; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK., Iacoangeli A; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.; Department of Biostatistics and Health Informatics, King's College London, London, UK., McArdle WL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Ho KM; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Kumar A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Chronic Disease Epidemiology unit, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Söderhäll C; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Soriano-Tárraga C; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain., Giralt-Steinhauer E; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain., Kazmi N; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Mason D; Bradford Institute for Health Research, Bradford, UK., McRae AF; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia., Corcoran DL; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA., Sugden K; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA., Kasela S; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Cardona A; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.; Department of Genetics, University of Cambridge, Cambridge, UK., Day FR; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Cugliari G; Department of Medical Sciences, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine, Turin, Italy., Viberti C; Department of Medical Sciences, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine, Turin, Italy., Guarrera S; Department of Medical Sciences, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine, Turin, Italy., Lerro M; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., Gupta R; Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Bollepalli S; Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Mandaviya P; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Zeng Y; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China., Clarke TK; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK., Walker RM; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Schmoll V; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany., Czamara D; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany., Ruiz-Arenas C; ISGlobal, Barcelona Global Health Institute, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain., Rezwan FI; Department of Computer Science, Aberystwyth University, Aberystwyth, UK., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin T; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia., Awaloff Y; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany., Germain M; INSERM UMR_S 1219, Bordeaux Population Health Center, University of Bordeaux, Bordeaux, France., Aïssi D; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany., Zwamborn R; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van Eijk K; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Dekker A; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., van Dongen J; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Hottenga JJ; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Willemsen G; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Xu CJ; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute Groningen, Groningen, the Netherlands.; CiiM and TWINCORE, Hannover Medical School and Helmholtz Centre for Infection Research, Hannover, Germany., Barturen G; Pfizer-University of Granada-Andalusian Government Center for Genomics and Oncological Research, Granada, Spain., Català-Moll F; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme, Bellvitge Biomedical Research Institute, Barcelona, Spain., Kerick M; Instituto de Parasitología y Biomedicina López Neyra, CSIC, Granada, Spain., Wang C; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, Australia., Melton P; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, Australia.; School of Global Population Health, Faculty of Health and Medical Sciences, University of Western Australia, Perth, Australia.; School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, Australia., Elliott HR; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Shin J; The Hospital for Sick Children, University of Toronto, Toronto, Canada., Bernard M; The Hospital for Sick Children, University of Toronto, Toronto, Canada., Yet I; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Bioinformatics, Institute of Health Sciences, Hacettepe University, Ankara, Turkey., Smart M; Institute for Social and Economic Research, University of Essex, Colchester, UK., Gorrie-Stone T; School of Life Sciences, University of Essex, Colchester, UK., Shaw C; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.; Department of Neurology, King's College Hospital, London, UK., Al Chalabi A; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.; Department of Neurology, King's College Hospital, London, UK.; United Kingdom Dementia Research Institute, King's College London, London, UK., Ring SM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Pershagen G; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Melén E; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden., Jiménez-Conde J; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain., Roquer J; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain., Lawlor DA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Wright J; Bradford Institute for Health Research, Bradford, UK., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Montgomery GW; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia., Moffitt TE; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical School, Durham, NC, USA.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Poulton R; Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Perry JRB; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Ong KK; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wareham NJ; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Matullo G; Department of Medical Sciences, University of Turin, Turin, Italy.; Italian Institute for Genomic Medicine, Turin, Italy., Sacerdote C; Italian Institute for Genomic Medicine, Turin, Italy.; Piemonte Centre for Cancer Prevention, Turin, Italy., Panico S; Dipartimento Di Medicina Clinica E Chirurgia, Federico II University, Naples, Italy., Caspi A; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.; Department of Psychiatry and Behavioral Sciences, Duke University Medical School, Durham, NC, USA.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Arseneault L; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Gagnon F; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., Ollikainen M; Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Kaprio J; Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Felix JF; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Rivadeneira F; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Tiemeier H; Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, MA, USA., van IJzendoorn MH; Department of Psychology, Education and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands.; Department of Clinical, Educational and Health Psychology, Division on Psychology and Language Sciences, Faculty of Brain Sciences, University College London, London, UK., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Jaddoe VWV; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Haley C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., McIntosh AM; Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Evans KL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Murray A; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Nohr EA; Research Unit for Gynaecology and Obstetrics, Institute of Clinical research, University of Southern Denmark, Odense, Denmark.; Centre of Women's, Family and Child Health, University of South-Eastern Norway, Kongsberg, Norway., Sørensen TIA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health (Section of Epidemiology), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Morgen CS; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark., Binder EB; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Lucae S; Department of Translational Research in Psychiatry, Max-Planck-Institute of Psychiatry, Munich, Germany., Gonzalez JR; ISGlobal, Barcelona Global Health Institute, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain., Bustamante M; ISGlobal, Barcelona Global Health Institute, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain.; Center for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain., Sunyer J; ISGlobal, Barcelona Global Health Institute, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain.; Hospital del Mar Medical Research Institute, Barcelona, Spain., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Karmaus W; Division of Epidemiology, Biostatistics, and Environmental Health Sciences, School of Public Health, University of Memphis, Memphis, TN, USA., Zhang H; Division of Epidemiology, Biostatistics, and Environmental Health Sciences, School of Public Health, University of Memphis, Memphis, TN, USA., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK., Wray NR; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Australia., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Beekman M; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Slagboom PE; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Morange PE; C2VN, Aix-Marseille University, INSERM, INRAE, Marseille, France., Trégouët DA; INSERM UMR_S 1219, Bordeaux Population Health Center, University of Bordeaux, Bordeaux, France., Veldink JH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Davies GE; Avera Institute for Human Genetics, Sioux Falls, SD, USA., de Geus EJC; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Boomsma DI; Department of Biological Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Vonk JM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, GRIAC Research Institute Groningen, Groningen, the Netherlands., Brunekreef B; Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, the Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Koppelman GH; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute Groningen, Groningen, the Netherlands., Alarcón-Riquelme ME; Pfizer-University of Granada-Andalusian Government Center for Genomics and Oncological Research, Granada, Spain.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Huang RC; Telethon Kids Institute, University of Western Australia, Perth, Australia., Pennell CE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, Australia., van Meurs J; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Hughes AD; UCL Institute of Cardiovascular Science, London, UK., Tillin T; UCL Institute of Cardiovascular Science, London, UK., Chaturvedi N; UCL Institute of Cardiovascular Science, London, UK., Pausova Z; The Hospital for Sick Children, University of Toronto, Toronto, Canada., Paus T; Departments of Psychology and Psychiatry, University of Toronto, Toronto, Canada., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, UK., Schalkwyk LC; School of Life Sciences, University of Essex, Colchester, UK., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Australia., Davey Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute of Artificial Intelligence and Decision Support, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria., Gaunt TR; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Heijmans BT; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Mill J; University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UK., Relton CL; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Publikováno v: Nature genetics [Nat Genet] 2021 Sep; Vol. 53 (9), pp. 1311-1321. Date of Electronic Publication: 2021 Sep 06.

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype.

Autor: Fraser E; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Denney L; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Antanaviciute A; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Blirando K; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Vuppusetty C; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Zheng Y; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.; Department of Immunology and Microbiology, School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Repapi E; Department of Computational Biology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Iotchkova V; Department of Computational Biology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Taylor S; Department of Computational Biology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Ashley N; Single Cell Genomics Facility, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., St Noble V; Department of Thoracic Imaging, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Benamore R; Department of Thoracic Imaging, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Hoyles R; Department of Thoracic Imaging, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Clelland C; Department of Thoracic Imaging, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom., Rastrick JMD; Immunology Therapeutic Area, UCB Pharma, Slough, United Kingdom., Hardman CS; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Alham NK; Nuffield Department of Surgical Sciences and Oxford NIHR Biomedical Research Centre, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom., Rigby RE; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Simmons A; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Rehwinkel J; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Ho LP; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.; Oxford Interstitial Lung Disease Service, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Mar 05; Vol. 12, pp. 623430. Date of Electronic Publication: 2021 Mar 05 (Print Publication: 2021).

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Autor: Labuhn M, Perkins K, Matzk S, Varghese L, Garnett C, Papaemmanuil E, Metzner M, Kennedy A, Amstislavskiy V, Risch T, Bhayadia R, Samulowski D, Hernandez DC, Stoilova B, Iotchkova V, Oppermann U, Scheer C, Yoshida K, Schwarzer A, Taub JW, Crispino JD, Weiss MJ, Hayashi Y, Taga T, Ito E, Ogawa S, Reinhardt D, Yaspo ML, Campbell PJ, Roberts I, Constantinescu SN, Vyas P, Heckl D, Klusmann JH

Publikováno v: Cancer cell [Cancer Cell] 2019 Sep 16; Vol. 36 (3), pp. 340.