Zobrazeno 1 - 10
of 82
pro vyhledávání: '"V. Ibba"'
Publikováno v:
Reumatismo, Vol 60, Iss 1, Pp 57-60 (2011)
Hepatitis C virus (HCV) infection in the setting of Psoriatic Arthritis is an additional variable to be considered in the therapeutic approach to the disease because of the complications of an immunosuppressive treatment in the course of a chronic in
Externí odkaz:
https://doaj.org/article/04cdd25da5324d0695eb0881f8c113ae
Autor:
Mohamed A. Ghonim, Jihang Ju, Kusma Pyakurel, Salome V. Ibba, Mai M. Abouzeid, Hamada F. Rady, Shigemi Matsuyama, Luis Del Valle, A. Hamid Boulares
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background The DNA-dependent protein kinase (DNA-PK) complex comprises a catalytic (PRKDC) and two requisite DNA-binding (Ku70/Ku80) subunits. The role of the complex in repairing double-stranded DNA breaks (DSBs) is established, but its rol
Externí odkaz:
https://doaj.org/article/ab21f508a8dd4a0da29878d32d70148d
Autor:
V. Ibba, M. Piga, G. Porru, G. Passiu, A. Mameli, A. Vacca, A. Cauli, A. Mathieu, V. Mura, S. Anna
Publikováno v:
Reumatismo, Vol 59, Iss 1s, Pp 25-27 (2011)
Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied exte
Externí odkaz:
https://doaj.org/article/4eee5cf4cff14d9697b6f55b0ee0ccc7
Autor:
Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background We reported that PARP-1 regulates genes whose products are crucial for asthma, in part, by controlling STAT6 integrity speculatively through a calpain-dependent mechanism. We wished to decipher the PARP-1/STAT6 relationship in the
Externí odkaz:
https://doaj.org/article/06e8d087c8bf469fa6f8d3b011c19b21
Autor:
Dorota Wyczechowska, Amir A Al-Khami, Luis Del Valle, Augusto C Ochoa, Mohamed A Ghonim, Salome V Ibba, Abdelmetalab F Tarhuni, Youssef Errami, Hanh H Luu, Matthew J Dean, Ali H El-Bahrawy, Ilyes A Benslimane, A Hamid Boulares
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Poly(ADP-ribose) polymerase (PARP) inhibitors (eg, olaparib) are effective against BRCA-mutated cancers at/near maximum tolerated doses by trapping PARP-1 on damaged chromatin, benefitting only small patient proportions. The benefits of ta
Externí odkaz:
https://doaj.org/article/0ab6a481a7a4440b9a1ca39aaa96af03
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses
Autor:
Giulia Monticone, Zhi Huang, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Keli Xu, Samarpan Majumder, Barbara A. Osborne, Christine Loh, Lucio Miele
Publikováno v:
Frontiers in immunology. 13
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the effectiveness of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c66e57e48c8270a88c935fe26ada0f6
https://pubmed.ncbi.nlm.nih.gov/36090975
https://pubmed.ncbi.nlm.nih.gov/36090975
Autor:
Giulia Monticone, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Zhi Huang, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Samarpan Majumder, Keli Xu, Barbara A. Osborne, Christine Loh, Lucio Miele
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the efficacy of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1499160016e9fd40cbe8738775d92d
https://doi.org/10.1101/2022.03.15.484378
https://doi.org/10.1101/2022.03.15.484378
Autor:
Salome V. Ibba, Hanh H. Luu, Mohamed Ghonim, Cecilia Vittori, Matthew J. Dean, Giulia Monticone, Francesca Peruzzi, Augusto Ochoa, Lucio Miele, Hamid A. Boulares
Publikováno v:
Cancer Research. 82:4211-4211
Despite the availability of numerous new therapies including immune checkpoint inhibitors, patients with colon cancer are faced with limited treatment options. We recently demonstrated that low metronomic dose of PARP inhibitor synergizes with anti-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8dc9bdfdf759a5633c8caf257d07ae6
https://doi.org/10.1158/1538-7445.am2022-4211
https://doi.org/10.1158/1538-7445.am2022-4211
Autor:
Ilyes Benslimane, Mohamed A. Ghonim, A. Hamid Boulares, Hanh H Luu, Shaker A. Mousa, Jeffrey Wang, Salome V. Ibba, Kusma Pyakurel
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Journal of Translational Medicine
Journal of Translational Medicine
Background The efficacy of heparins and low-MW-heparins (LMWH) against human asthma has been known for decades. However, the clinical utility of these compounds has been hampered by their anticoagulant properties. Much effort has been put into harnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf48aa3f6f1e50b94a2e0f4ac001136
http://link.springer.com/article/10.1186/s12967-018-1621-5
http://link.springer.com/article/10.1186/s12967-018-1621-5
Autor:
S V, Ibba, C, Fenizia, P, Serna Ortega, V, Mercurio, I, Saulle, E M, Lori, D, Trabattoni, M, Clerici, M, Biasin
Publikováno v:
Journal of biological regulators and homeostatic agents. 33(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d98dd350757055343813a1a8be4c2ebe
https://pubmed.ncbi.nlm.nih.gov/31489808
https://pubmed.ncbi.nlm.nih.gov/31489808